X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (55588) 55588
Publication (8426) 8426
Book Chapter (1173) 1173
Conference Proceeding (993) 993
Book Review (605) 605
Magazine Article (338) 338
Dissertation (235) 235
Book / eBook (98) 98
Government Document (70) 70
Newspaper Article (48) 48
Paper (44) 44
Trade Publication Article (31) 31
Web Resource (11) 11
Photograph (10) 10
Data Set (7) 7
Music Score (6) 6
Reference (4) 4
Video Recording (3) 3
Art (2) 2
Journal / eJournal (2) 2
Market Research (2) 2
Standard (1) 1
Technical Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (18657) 18657
humans (18614) 18614
animals (13674) 13674
biochemistry & molecular biology (12837) 12837
double-strand breaks (11021) 11021
dna damage (10864) 10864
dna (10072) 10072
dna repair (9043) 9043
cell biology (7403) 7403
genetics & heredity (6419) 6419
strands (5414) 5414
base sequence (5268) 5268
homologous recombination (4935) 4935
mutation (4922) 4922
molecular sequence data (4889) 4889
proteins (4857) 4857
mice (4777) 4777
research (4689) 4689
analysis (4495) 4495
repair (4326) 4326
oncology (4299) 4299
strand breaks (4167) 4167
cancer (4082) 4082
male (3974) 3974
article (3929) 3929
saccharomyces-cerevisiae (3793) 3793
strand break repair (3787) 3787
toxicology (3729) 3729
female (3522) 3522
dna-binding proteins - metabolism (3328) 3328
cell line (3325) 3325
mammalian-cells (3325) 3325
deoxyribonucleic acid--dna (3277) 3277
biology (3237) 3237
genetic aspects (3106) 3106
biophysics (3043) 3043
apoptosis (2999) 2999
ionizing-radiation (2971) 2971
amino acid sequence (2925) 2925
cells (2895) 2895
biotechnology & applied microbiology (2771) 2771
recombination, genetic (2673) 2673
protein (2670) 2670
damage (2632) 2632
protein binding (2630) 2630
multidisciplinary sciences (2600) 2600
dna - metabolism (2535) 2535
dna - chemistry (2531) 2531
dna breaks, double-stranded (2511) 2511
dna-binding proteins - genetics (2499) 2499
escherichia-coli (2480) 2480
in-vitro (2460) 2460
phosphorylation (2447) 2447
dna replication (2430) 2430
research article (2378) 2378
gene expression (2371) 2371
genes (2365) 2365
dna-damage (2268) 2268
models, molecular (2251) 2251
radiology, nuclear medicine & medical imaging (2209) 2209
genetic research (2205) 2205
nucleic acid conformation (2184) 2184
recombination (2174) 2174
cell cycle (2150) 2150
kinetics (2148) 2148
cell line, tumor (2134) 2134
virology (2121) 2121
replication (2092) 2092
chemistry, multidisciplinary (2039) 2039
binding (2021) 2021
deoxyribonucleic acid (2009) 2009
strand (1983) 1983
expression (1970) 1970
genomics (1934) 1934
genomes (1919) 1919
physiological aspects (1914) 1914
rna (1912) 1912
saccharomyces cerevisiae - genetics (1906) 1906
radiation (1905) 1905
binding sites (1867) 1867
chromatin (1857) 1857
transcription, genetic (1821) 1821
oxidative stress (1815) 1815
cells, cultured (1811) 1811
microbiology (1798) 1798
polymerase chain reaction (1742) 1742
single-strand specific dna and rna endonucleases (1712) 1712
enzymes (1701) 1701
gene (1698) 1698
genetics (1697) 1697
in-vivo (1692) 1692
dna strand breaks (1690) 1690
genomic instability (1681) 1681
histones - metabolism (1674) 1674
comet assay (1655) 1655
yeast (1642) 1642
chromosomes (1635) 1635
life sciences (1615) 1615
dna repair - genetics (1594) 1594
molecular biology (1578) 1578
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (37) 37
Collection Dvlpm't (Acquisitions) - Vendor file (9) 9
UTL at Downsview - May be requested (9) 9
UofT at Mississauga - Stacks (8) 8
UofT at Scarborough - Stacks (8) 8
Collection Dvlpm't (Acquisitions) - Closed Orders (7) 7
Online Resources - Online (7) 7
Earth Sciences (Noranda) - Stacks (4) 4
Media Commons - Audio Visual (3) 3
Music - Stacks (3) 3
Gerstein Science - Stacks (2) 2
Massey College (Robertson Davies) - Rare Book (2) 2
Robarts - Protected Material (2) 2
Royal Ontario Museum - Stacks (2) 2
Thomas Fisher Rare Book - Rare Book (2) 2
Trinity College (John W Graham) - Storage (2) 2
Victoria University E.J. Pratt - Stacks (2) 2
Art - Library use only (1) 1
Art - Oversize (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Gerstein Science - Theses (1) 1
Innis College - Stacks (1) 1
Media Commons - Microtexts (1) 1
New College (Ivey) - Stacks (1) 1
UofT Schools - Stacks (1) 1
UofT at Mississauga - Oversize (1) 1
UofT at Mississauga - Reference (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
Victoria University E.J. Pratt - Reference (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (56310) 56310
Chinese (488) 488
Japanese (256) 256
French (129) 129
German (102) 102
Korean (82) 82
Russian (78) 78
Swedish (52) 52
Polish (32) 32
Portuguese (27) 27
Spanish (18) 18
Croatian (11) 11
Turkish (8) 8
Czech (6) 6
Dutch (5) 5
Persian (5) 5
Danish (4) 4
Italian (4) 4
Thai (2) 2
Arabic (1) 1
Bosnian (1) 1
Hungarian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


ACS Chemical Biology, ISSN 1554-8929, 01/2011, Volume 6, Issue 1, pp. 47 - 60
In the 12 years since the process of RNA interference (RNAi) was first discovered, great progress has been made in understanding its mechanism and exploiting... 
siRNA or miRNA seed sequence | RISC | microRNA (miRNA) | GENOME-WIDE RNAI | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE IMMUNE-RESPONSE | Short interfering RNA (siRNA) | FUNCTIONAL DISSECTION | MAMMALIAN-CELLS | DEPENDENT STIMULATION | SMALL INTERFERING RNAS | MESSENGER-RNAS | RNA Interference | RNAI off-target effect | GENE-EXPRESSION | C-ELEGANS | siRNA multiplicity validation | HIV-1 REPLICATION | RNA, Small Interfering - genetics | Gene Expression | Down-Regulation | Genomics | RNA, Messenger - genetics | Untranslated Regions | Validation Studies as Topic | Transcription, Genetic | MicroRNAs - genetics | RNA, Double-Stranded - chemistry | Genetic Techniques - standards | RNA, Small Interfering - metabolism | Short interfering RNA (siRNA): An endogenous or artificial (synthetic) small double strand RNA with perfect pairing of the two strands. One strand (called the guide strand) targets RISC to perfectly complementary mRNAs, resulting in endonucleolytic cleavage of the mRNA by the RISC component Ago2 | siRNA or miRNA seed sequence: The 5′ region of the guide strand of an siRNA or miRNA sequence, extending from nucleotides 2–7 (hexamer) or 2–8 (heptamer) | or mRNA decay | siRNA multiplicity validation: Validation of a gene-phenotype association by showing that the phenotype can be produced by multiple independent siRNAs that target different regions of the same mRNA | MicroRNA (miRNA): A mature endogenous small double strand RNA, often with imperfect pairing of the two strands, originating from processing of a precursor RNA molecule by cellular RNases. miRNAs target RISC complexes to sites that have imperfect sequence complementarity, and that are typically located in the 3′ untranslated region of the mRNA | RISC: The RNA-Induced Silencing Complexes are multi-protein complexes containing an Argonaute protein, a small single strand RNA and additional regulatory proteins | RNA interference: A cellular process that downregulates gene expression at a post-transcriptional step. One strand of a small double strand RNA (siRNA or miRNA) integrates in a protein complex called RISC and targets an mRNA with sequence complementarity for cleavage, translation inhibition and | RNAi off-target effect: Any effect of an RNAi-based treatment that is a consequence of reducing the expression of an unintended target
Journal Article
2015, Limited edition broadside., Volume no. 58, 2 broadsides
Book
Journal
2011, Photo poche, ISBN 2742793550, Volume 131., 1 v. (unpaged)
Book
2002, 1st Ballantine ed., Ballantine reader's circle, ISBN 9780449003718, xx, 284, [13]
Book
eBook
1998, ISBN 2869593880, 122, [3]
Book
Engineering Structures, ISSN 0141-0296, 12/2013, Volume 57, pp. 475 - 483
Journal Article
Analytical Methods, ISSN 1759-9660, 01/2019, Volume 11, Issue 10, pp. 1331 - 1337
Herein we propose a label-free and sensitive detection method for coralyne and heparin, based on utilizing the complex of adenosine16 (A16) and coralyne to... 
Sequences | Strands | Fluorescence | Heparin
Journal Article
DNA Repair, ISSN 1568-7864, 09/2019, Volume 81, p. 102664
The human gene that encodes XRCC1 was cloned nearly thirty years ago but experimental analysis of this fascinating protein is still unveiling new insights into... 
Non-homologous end-joining (NHEJ) | Single-strand break repair (SSBR) | Double-strand break repair (DSBR) | DNA single-strand break (SSB) | DNA double-strand break (DSB)
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.