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1. Full Text Incidence of Pneumococcal Disease Due to Non-Pneumococcal Conjugate Vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination, 1998-2004
by Lauri A. Hicks and Lee H. Harrison and Brendan Flannery and James L. Hadler and William Schaffner and Allen S. Craig and Delois Jackson and Ann Thomas and Bernard Beall and Ruth Lynfield and Arthur Reingold and Monica M. Farley and Cynthia G. Whitney and Active Bacterial Core Surveillance and Active Bacterial Core Surveillance Program of the Emerging Infections Program Network
The Journal of Infectious Diseases, ISSN 0022-1899, 11/2007, Volume 196, Issue 9, pp. 1346 - 1354
Background. Widespread use of pneumococcal conjugate vaccine (PCV7) resulted in decreases in invasive disease among children and elderly persons. The benefits... 
Conjugate vaccines | Vaccination | Mortality | Bacteria | Disease susceptibility | Adults | Preventive medicine | Diabetes | Epidemiology | Older adults | Streptococcus pneumoniae | REPLACEMENT | INFECTIOUS DISEASES | INVASIVE-DISEASE | IMPACT | DAY-CARE-CENTERS | STREPTOCOCCUS-PNEUMONIAE INFECTIONS | ADULTS | COLONIZATION | EPIDEMIOLOGY | NASOPHARYNGEAL CARRIAGE | CHILDREN | United States - epidemiology | Streptococcus pneumoniae - classification | Age Distribution | Humans | Child, Preschool | Incidence | Streptococcus pneumoniae - immunology | Pneumococcal Infections - epidemiology | Time Factors | Drug Resistance, Multiple, Bacterial | Pneumococcal Vaccines - immunology | Pneumococcal Infections - microbiology | Aged | Anti-Bacterial Agents - pharmacology | Population Surveillance | Serotyping | Prevention | Causes of | Physiological aspects | Dosage and administration | Forecasts and trends | Research | Pneumococcal infections
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2. Full Text Pneumococcal serotypes before and after introduction of conjugate vaccines, United States, 1999-2011
by Richter, Sandra S and Heilmann, Kristopher P and Dohrn, Cassie L and Riahi, Fathollah and Diekema, Daniel J and Doern, Gary V
Emerging Infectious Diseases, ISSN 1080-6040, 07/2013, Volume 19, Issue 7, pp. 1074 - 1083
Serotyping data for pneumococci causing invasive and noninvasive disease in 2008-2009 and 2010-2011 from >= 43 US centers were compared with data from... 
INFECTIOUS DISEASES | IMPACT | ADULTS | RISK | 19A | IMMUNOLOGY | RESISTANT STREPTOCOCCUS-PNEUMONIAE | ASSOCIATION | EPIDEMIOLOGY | Streptococcus pneumoniae - classification | Age Distribution | Prevalence | United States | Humans | Middle Aged | Child, Preschool | Infant | Pneumococcal Vaccines | Streptococcus pneumoniae - immunology | Microbial Sensitivity Tests | Young Adult | Penicillin Resistance | Adult | Pneumococcal Infections - microbiology | Vaccines, Conjugate | Penicillins - pharmacology | Child | Serotyping | Streptococcus pneumoniae - drug effects | Pneumococcal Infections - epidemiology | Adolescent | Pneumococcal Infections - prevention & control | Aged | Anti-Bacterial Agents - pharmacology | Cluster Analysis | Prevention | Usage | Conjugate vaccines | Research | Health aspects | Statistics | Pneumococcal infections | Risk factors | Streptococcus pneumoniae | pathogenesis | vaccine | bacteria | serotype | conjugate vaccines
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3. Full Text Increased Penicillin Nonsusceptibility of Nonvaccine-Serotype Invasive Pneumococci Other than Serotypes 19A and 6A in Post–7-Valent Conjugate Vaccine Era
by Robert E. Gertz and Zhongya Li and Fabiana C. Pimenta and Delois Jackson and Billie A. Juni and Ruth Lynfield and James H. Jorgensen and Maria da Gloria Carvalho and Bernard W. Beall and Active Bacterial Core Surveillance and Active Bacterial Core Surveillance Team
The Journal of Infectious Diseases, ISSN 0022-1899, 3/2010, Volume 201, Issue 5, pp. 770 - 775
According to population-based invasive pneumococcal surveillance in the United States during 2007, 898 (26%) of 3,511 isolates were penicillin nonsusceptible.... 
BACTERIA | Conjugate vaccines | Surveillance | Antibiotics | Vaccination | Respiratory diseases | Penicillin | Infections | Preventive medicine | Epidemiology | Streptococcus pneumoniae | UNITED-STATES | INFECTIOUS DISEASES | STREPTOCOCCUS-PNEUMONIAE | DISEASE | ADULTS | MICROBIOLOGY | IMMUNOLOGY | CLONE | CHILDREN | United States - epidemiology | Streptococcus pneumoniae - classification | Streptococcus pneumoniae - drug effects | Prevalence | DNA Fingerprinting | Humans | Child, Preschool | Genotype | Heptavalent Pneumococcal Conjugate Vaccine | Infant | Male | Sequence Analysis, DNA | Streptococcus pneumoniae - isolation & purification | Penicillin Resistance | Bacterial Typing Techniques | Pneumococcal Vaccines - immunology | Female | Pneumococcal Infections - microbiology | Anti-Bacterial Agents - pharmacology | Penicillins - pharmacology | Child | Infant, Newborn | Serotyping | Cluster Analysis | Genetic aspects | Dosage and administration | Research | Pneumococcal infections
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4. Full Text Distribution of 13-Valent Pneumococcal Conjugate Vaccine Streptococcus pneumoniae Serotypes in US Adults Aged ≥50 Years With Community-Acquired Pneumonia
by Robert L. Sherwin and Sharon Gray and Ronika Alexander and Paul C. McGovern and Jay Graepel and Michael W. Pride and Jay Purdy and Peter Paradiso and Thomas M. File
The Journal of Infectious Diseases, ISSN 0022-1899, 12/2013, Volume 208, Issue 11, pp. 1813 - 1820
Background. Streptococcus pneumoniae causes a substantial proportion of community-acquired pneumonia (CAP) and healthcare-associated pneumonia (HCAP) in the... 
Urine | Pneumonia | BACTERIA | Conjugate vaccines | Pneumococcal pneumonia | Vaccination | Mortality | Adults | Epidemiology | Diseases | Streptococcus pneumoniae | UNITED-STATES | POPULATION | INFECTIOUS DISEASES | EFFICACY | CARE-ASSOCIATED PNEUMONIA | OLDER-ADULTS | urinary antigen detection assay | MICROBIOLOGY | IMMUNOLOGY | community-acquired pneumonia | 13-valent pneumococcal conjugate vaccine | IMMUNIZATION | DISEASE | serotype distribution | healthcare-associated pneumonia | COHORT | pneumococcal serotypes | POLYSACCHARIDE VACCINE | EPIDEMIOLOGY | United States - epidemiology | Streptococcus pneumoniae - classification | Demography | Prevalence | Prospective Studies | Community-Acquired Infections - epidemiology | Species Specificity | Humans | Middle Aged | Cross Infection | Male | Streptococcus pneumoniae - immunology | Vaccines, Conjugate - immunology | Pneumococcal Infections - immunology | Polysaccharides | Aged, 80 and over | Female | Pneumococcal Infections - microbiology | Community-Acquired Infections - immunology | Serotyping | Cross-Sectional Studies | Pneumococcal Infections - epidemiology | Hospitals | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | Aged | Community-Acquired Infections - prevention & control | Community-Acquired Infections - microbiology | Demographic aspects | Community-acquired infections | Bacterial pneumonia | Distribution | Research
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5. Full Text Biochemical, genetic, and serological characterization of two capsule subtypes among Streptococcus pneumoniae serotype 20 strains: Discovery of a new pneumococcal serotype
by Calix, Juan J and Porambo, Richard J and Brady, Allison M and Larson, Thomas R and Yother, Janet and Abeygunwardana, Chitrananda and Nahm, Moon H
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 33, pp. 27885 - 27894
The bacterial pathogen Streptococcus pneumoniae expresses one of over 90 structurally distinct polysaccharide (PS) capsule serotypes. Prior PS structural... 
ANTIBODIES | CARRIAGE | ASSAY | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | SEROGROUP-6 | POLYSACCHARIDE VACCINE | LOCUS | CHILDREN | WCJE | Rabbits | Streptococcus pneumoniae - classification | Species Specificity | Bacterial Capsules - metabolism | Humans | Antibodies, Monoclonal, Murine-Derived - chemistry | Bacterial Proteins - genetics | Polysaccharides, Bacterial - metabolism | Oligosaccharides - metabolism | Serotyping - methods | Polysaccharides, Bacterial - genetics | Glycosyltransferases - metabolism | Animals | Streptococcus pneumoniae - metabolism | Bacterial Capsules - genetics | Streptococcus pneumoniae - genetics | Bacterial Proteins - metabolism | Mice | Glycosyltransferases - genetics | Mutation | Oligosaccharides - genetics | O-Acetylation | Polysaccharide Capsule | S. pneumoniae | Glycobiology | Streptococcus | Microbiology | Serotype 20 | Bacteria | Polysaccharide
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6. Full Text Serotype 3 remains the leading cause of invasive pneumococcal disease in adults in portugal (2012-2014) despite continued reductions in other 13-valent conjugate vaccine serotypes
by Horácio, Andreia N and Silva-Costa, Catarina and Lopes, Joana P and Ramirez, Mário and Melo-Cristino, José and Vaz, Teresa and Gião, Marília and Ferreira, Rui and Fonseca, Ana Buschy and Oliveira, Henrique and Silva, Ana Cristina and Costa, Hermínia and Silva, Maria Fátima and Afonso, Maria Amélia and Pinto, Margarida and Chantre, Odete and Marques, João and Peres, Isabel and Daniel, Isabel and Canas, Ema and Ferreira, Teresa and Marcelo, Cristina and Monteiro, Lurdes and Lito, Luís Marques and Martins, Filomena and Pessanha, Maria Ana and Gonçalves, Elsa and Morais, Teresa and Marques, Teresa and Toscano, Cristina and Lopes, Paulo and Felício, Luísa and Lameirão, Angelina and Vieira, Ana Paula Mota and Tomaz, Margarida and Bento, Rosa and Ramos, Maria Helena and Castro, Ana Paula and Fonseca, Fernando and Ribeiro, Graça and Tomé, Rui and Pontes, Celeste and Boaventura, Luísa and Chaves, Catarina and Reis, Teresa and Canhoto, Nuno and Afonso, Teresa and Pina, Teresa and Peres, Helena and Fontes, Ilse and Martinho, Paulo and Domingos, Ana and Marrão, Gina and Grossinho, José and Ribeiro, Manuela and Gonçalves, Helena and Faustino, Alberta and Alves, Adelaide and Iglesias, Maria Cármen and Pinheiro, Maria Paula and Semedo, R and Coutinho, Adriana and Cabral, Luísa and Neto, Olga and Sancho, Luísa and Diogo, José and Rodrigues, Ana and Nascimento, Isabel and Ramalheira, Elmano and Bessa, Fernanda and Diaz, Raquel and Vale, Isabel and Carvalho, Ana and Ribeiro, José Miguel and Read, Maria Antónia and Alves, Valquíria and Monteiro, Margarida and Raposo, Engrácia and Magalhães, Maria Lurdes and Rochas, Helena and Silva, Anabela and Rodrigues, Margarida and Freitas, José Mota and Vieira, Sandra and Meneses, Maria Favila and de Sousa, José Germano and Viana, Mariana Bettencourt and Terra, Isaura and Rodrigues, Vitória and Pereira, Patrícia and Duarte, Jesuína and Pinto, Paula and Moreira, Ezequiel and Ferreira, João Ataíde and Vicente, Adília and Paixão, Paulo and Novais, Natália and Portuguese Grp Study Streptococcal and Portuguese Group for the Study of Streptococcal Infections
Frontiers in Microbiology, ISSN 1664-302X, 10/2016, Volume 7, p. 1616
Since 2010 the 13-valent pneumococcal conjugate vaccine (PCV13) replaced the 7-valent vaccine (PCV7) as the leading pneumococcal vaccine used in children... 
Polysaccharide vaccine | Conjugate vaccines | Antimicrobial resistance | Invasive disease | Serotype | Streptococcus pneumoniae | IMPACT | INFECTIONS | STREPTOCOCCUS-PNEUMONIAE | TYPING METHODS | SURVEILLANCE | MICROBIOLOGY | COHORT | Drug resistance in microorganisms | Care and treatment | Research | Pneumococcal vaccine | Health aspects | Pneumococcal infections | Risk factors | antimicrobial resistance | serotype | conjugate vaccines
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7. Full Text Epidemiological differences among pneumococcal serotypes
by Hausdorff, William P and Feikin, Daniel R and Klugman, Keith P
The Lancet Infectious Diseases, ISSN 1473-3099, 2005, Volume 5, Issue 2, pp. 83 - 93
The bacterial species consists of 90 immunologically distinct serotypes, of which some possess distinct epidemiological properties. Certain serotypes are much... 
UNITED-STATES | INFECTIOUS DISEASES | INVASIVE-DISEASE | CONJUGATE VACCINE | IMMUNODEFICIENCY-VIRUS-INFECTION | ACUTE OTITIS-MEDIA | ANTIBIOTIC SUSCEPTIBILITY | MOLECULAR EPIDEMIOLOGY | RESISTANT STREPTOCOCCUS-PNEUMONIAE | ANTIMICROBIAL RESISTANCE | CAPSULAR TYPES | Vaccines, Conjugate - administration & dosage | Pneumococcal Infections - epidemiology | Vaccines, Conjugate - immunology | Streptococcus pneumoniae - classification | Streptococcus pneumoniae - isolation & purification | Humans | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - administration & dosage | Streptococcus pneumoniae - immunology | Pneumonia | Infants | Epidemiology | Health aspects | Bacterial pneumonia
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8. Full Text Serotype replacement in disease after pneumococcal vaccination
by Weinberger, Daniel M, Dr and Malley, Richard, MD and Lipsitch, Marc, DPhil
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9807, pp. 1962 - 1973
Summary Vaccination with heptavalent pneumococcal conjugate vaccine (PCV7) has significantly reduced the burden of pneumococcal disease and has had an... 
Internal Medicine | CHANGING EPIDEMIOLOGY | MEDICINE, GENERAL & INTERNAL | CONJUGATE VACCINE | CARE-CENTER ATTENDEES | INVASIVE DISEASE | STREPTOCOCCUS-PNEUMONIAE SEROTYPES | ACUTE OTITIS-MEDIA | HAEMOPHILUS-INFLUENZAE | TEMPORAL TRENDS | ANTIMICROBIAL RESISTANCE | NASOPHARYNGEAL CARRIAGE | Streptococcus pneumoniae - classification | Humans | Carrier State - microbiology | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | Heptavalent Pneumococcal Conjugate Vaccine | Pneumococcal Infections - microbiology | Serotyping | Streptococcus pneumoniae - immunology | Pneumococcal vaccine | Health aspects | Research | Prevention | Usage | Pneumonia, Pneumococcal | Pneumonia | Vaccines | Epidemiology | Developing countries--LDCs | Streptococcus infections
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9. Full Text Invasive serotype 35B pneumococci including an expanding serotype switch lineage, United States, 2015–2016
by Chochua, Sopio and Metcalf, Benjamin J and Li, Zhongya and Walker, Hollis and Tran, Theresa and McGee, Lesley and Beall, Bernard
Emerging Infectious Diseases, ISSN 1080-6040, 06/2017, Volume 23, Issue 6, pp. 922 - 930
We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United... 
INFECTIOUS DISEASES | CONJUGATE VACCINE | NONSUSCEPTIBILITY | PHYLOGENETIC ANALYSIS | 19A | IMMUNOLOGY | RESISTANT STREPTOCOCCUS-PNEUMONIAE | MULTIDRUG-RESISTANCE | VIRULENCE | EMERGENCE | GENOME | CHILDREN | Genome, Bacterial | Streptococcus pneumoniae - classification | Streptococcus pneumoniae - drug effects | United States | Humans | Serogroup | Genotype | Streptococcus pneumoniae - immunology | Pneumococcal Infections - epidemiology | Penicillin Resistance | Streptococcus pneumoniae - genetics | Pneumococcal Infections - microbiology | Gene Expression Regulation, Bacterial | Serotyping | Research | Streptococcus pneumoniae | pneumococcal 7-valent conjugate vaccine | pneumococcal 13-valent conjugate vaccine | recombination | bacteria | vaccines | Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage, United States, 2015–2016 | pneumococcal conjugate | serotype 35B | invasive pneumococcal disease | serotype expansion | respiratory infections | penicillin-binding protein types | switch lineage | pneumococci | serotype switch | surveillance
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10. Full Text Changing serotypes causing childhood invasive pneumococcal disease: Massachusetts, 2001-2007
by Hsu, Katherine K and Shea, Kimberly M and Stevenson, Abbie E and Pelton, Stephen I and Massachusetts Department of Public Health and Massachusetts Dept Public Hlth
Pediatric Infectious Disease Journal, ISSN 0891-3668, 2010, Volume 29, Issue 4, pp. 289 - 293
Heptavalent pneumococcal conjugate vaccine (PCV7) was licensed in the United States in February 2000 and distributed in Massachusetts, starting in July 2000... 
Population surveillance | Conjugate vaccines | Childhood invasive pneumococcal disease | Serotyping | Streptococcus pneumoniae - classification | Streptococcus pneumoniae - drug effects | Humans | Child, Preschool | Drug Resistance, Bacterial | Pneumococcal Infections - mortality | Heptavalent Pneumococcal Conjugate Vaccine | Infant | Pneumococcal Vaccines - administration & dosage | Massachusetts - epidemiology | Incidence | Streptococcus pneumoniae - immunology | Microbial Sensitivity Tests | Pneumococcal Infections - epidemiology | Streptococcus pneumoniae - isolation & purification | Immunization Programs | Pneumococcal Infections - prevention & control | Pneumococcal Infections - microbiology | Anti-Bacterial Agents - pharmacology | Infant, Newborn | Population Surveillance - methods | serotyping | INFECTIOUS DISEASES | STREPTOCOCCUS-PNEUMONIAE | population surveillance | CONJUGATE VACCINE | ERA | childhood invasive pneumococcal disease | conjugate vaccines | 19A | PEDIATRICS | IMMUNOLOGY | CHILDREN
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11. Full Text Systematic evaluation of serotypes causing invasive pneumococcal disease among children under five: The pneumococcal global serotype project
by Johnson, Hope L and Deloria-Knoll, Maria and Levine, Orin S and Stoszek, Sonia K and Hance, Laura Freimanis and Reithinger, Richard and Muenz, Larry R and O'Brien, Katherine L
PLoS Medicine, ISSN 1549-1277, 10/2010, Volume 7, Issue 10, p. e1000348
Background: Approximately 800,000 children die each year due to pneumococcal disease and >90% of these deaths occur in developing countries where few children... 
SURVEILLANCE | MEDICINE, GENERAL & INTERNAL | STREPTOCOCCUS-PNEUMONIAE | CONJUGATE VACCINE | Streptococcus pneumoniae - classification | Humans | Child, Preschool | Infant | Disease Progression | Serotyping - methods | Streptococcus pneumoniae - immunology | Pneumococcal Infections - blood | Internationality | Vaccines, Conjugate - therapeutic use | Pneumococcal Infections - prevention & control | Pneumococcal Infections - classification | Infant, Newborn | Prevention | Care and treatment | Pneumonia | Usage | Bacterial pneumonia | Meningitis | Research | Pneumococcal vaccine | Health aspects | Risk factors | Prevalence studies (Epidemiology) | Studies | Lifesaving | Decision making | Mortality | Vaccines | Children & youth
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12. Full Text Serotype-independent pneumococcal vaccines
by Miyaji, Eliane Namie and Miyaji, Eliane Namie and Oliveira, Maria Leonor Sarno and Oliveira, Maria Leonor Sarno and Carvalho, Eneas and Carvalho, Eneas and Ho, Paulo Lee and Ho, Paulo Lee
Cellular and Molecular Life Sciences, ISSN 1420-682X, 9/2013, Volume 70, Issue 18, pp. 3303 - 3326
Streptococcus pneumoniae remains an important cause of disease with high mortality and morbidity, especially in children and in the elderly. The widespread use... 
Life Sciences | Biochemistry, general | Life Sciences, general | Vaccine | Biomedicine general | Cell Biology | Streptococcus pneumoniae | CONJUGATE VACCINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | WHOLE-CELL VACCINE | ATTENUATED SALMONELLA VACCINE | DELAYED ANTIGEN SYNTHESIS | CELL BIOLOGY | INDUCE SALIVARY ANTIBODIES | ACUTE OTITIS-MEDIA | CHOLINE-BINDING PROTEINS | CROSS-REACTIVE ANTIBODIES | SURFACE PROTEIN-A | STREPTOCOCCUS-PNEUMONIAE COLONIZATION | Meningitis, Bacterial - microbiology | Humans | Pneumococcal Vaccines - therapeutic use | Clinical Trials as Topic | Meningitis, Bacterial - immunology | Vaccines, Conjugate - immunology | Pneumococcal Infections - immunology | Animals | Mucous Membrane - immunology | Recombinant Proteins - immunology | Vaccines, Conjugate - therapeutic use | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | Antigens - immunology | Pneumococcal Infections - microbiology | Mice | Serotyping | Disease Models, Animal | Polysaccharides | Pneumonia | Vaccines | Analysis | Bacterial pneumonia | Clinical trials | Streptococcus infections
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