X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (52) 52
index medicus (51) 51
cancer (48) 48
stroma (41) 41
oncology (33) 33
animals (29) 29
fibroblasts (27) 27
cell biology (26) 26
metastasis (26) 26
tumors (26) 26
research (21) 21
microenvironment (20) 20
oxidative stress (19) 19
development and progression (17) 17
proteins (17) 17
tumor microenvironment (17) 17
cell line, tumor (16) 16
expression (16) 16
tumor stroma (16) 16
biology (15) 15
cancer-associated fibroblasts (15) 15
growth (15) 15
mice (15) 15
multidisciplinary sciences (15) 15
breast-cancer (14) 14
care and treatment (14) 14
female (14) 14
genetic aspects (14) 14
stromal cells - metabolism (14) 14
breast cancer (13) 13
gene expression (13) 13
male (13) 13
cell proliferation (12) 12
medicine (12) 12
neoplasms - pathology (12) 12
tumor-stroma coevolution (12) 12
carcinoma (11) 11
fibroblasts - metabolism (11) 11
fibroblasts - pathology (11) 11
science (11) 11
stem cells (11) 11
angiogenesis (10) 10
biochemistry & molecular biology (10) 10
metabolism (10) 10
prostate cancer (10) 10
analysis (9) 9
autophagy (9) 9
cell growth (9) 9
coculture techniques (9) 9
disease progression (9) 9
epithelial-mesenchymal transition (9) 9
extracellular matrix (9) 9
gene expression regulation, neoplastic (9) 9
gene-expression (9) 9
metastases (9) 9
progression (9) 9
research article (9) 9
stromal cells - pathology (9) 9
tumorigenesis (9) 9
apoptosis (8) 8
cells (8) 8
hypoxia (8) 8
inflammation (8) 8
neoplasms - metabolism (8) 8
prostatic neoplasms - pathology (8) 8
review (8) 8
signal transduction (8) 8
article (7) 7
breast (7) 7
breast neoplasms - metabolism (7) 7
breast neoplasms - pathology (7) 7
carcinoma-associated fibroblasts (7) 7
kinases (7) 7
mice, nude (7) 7
oncology, experimental (7) 7
pathology (7) 7
prostate-cancer (7) 7
stromal fibroblasts (7) 7
aerobic glycolysis (6) 6
binding (6) 6
bioscience (6) 6
calcium (6) 6
cancer cells (6) 6
carcinoma - pathology (6) 6
cell (6) 6
cell transformation, neoplastic - genetics (6) 6
cell transformation, neoplastic - pathology (6) 6
cycle (6) 6
cytokines (6) 6
enzymes (6) 6
epithelial cells - metabolism (6) 6
invasion (6) 6
invasiveness (6) 6
landes (6) 6
models, biological (6) 6
organogenesis (6) 6
physiological aspects (6) 6
prognosis (6) 6
prostatic neoplasms - genetics (6) 6
prostatic neoplasms - metabolism (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Genetics, ISSN 1061-4036, 05/2008, Volume 40, Issue 5, pp. 494 - 495
The progression of carcinomas to high- grade malignancies is accompanied by profound histological changes in the tumor-associated stroma. Although previous... 
CELLS | GENETICS & HEREDITY | STROMA | MUTATIONS | TP53 | BREAST | GENETIC ALTERATIONS | Carcinoma - genetics | Carcinoma - pathology | Stromal Cells - pathology | Mesoderm - pathology | Humans | Analysis | Stem cells | Physiological aspects | Development and progression | Genetic aspects | Tumors | Cancer | Studies | Changes | Carbon dioxide | Evolution | Cells
Journal Article
Nature Cell Biology, ISSN 1465-7392, 04/2015, Volume 17, Issue 4, pp. 351 - 359
Journal Article
CELL CYCLE, ISSN 1538-4101, 04/2011, Volume 10, Issue 8, pp. 1271 - 1286
Previously, we showed that high-energy metabolites (lactate and ketones) "fuel" tumor growth and experimental metastasis in an in vivo xenograft model, most... 
OXIDATIVE STRESS | breast cancer | metformin | AUTOPHAGY | ketones | HYPOXIA | FIBROBLASTS | personalized medicine | CELL BIOLOGY | recurrence | MICROENVIRONMENT | clinical outcome | metastasis | metabologenomics | GENE-EXPRESSION | TUMOR-STROMA COEVOLUTION | LACTIC-ACIDOSIS | cancer stem cells | lactate | oxidative mitochondrial metabolism | ENERGY-METABOLISM
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2018, Volume 24, Issue 4, pp. 463 - 473
Breast tumors of the basal-like, hormone receptor-negative subtype remain an unmet clinical challenge, as there is high rate of recurrence and poor survival in... 
INTERNATIONAL EXPERT CONSENSUS | MEDICINE, RESEARCH & EXPERIMENTAL | PRIMARY THERAPY | CARCINOMA-ASSOCIATED FIBROBLASTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIGHLIGHTS | CELL BIOLOGY | LUMINAL SUBTYPE | MOLECULAR PORTRAITS | MAMMARY-TUMORS | PDGFR-ALPHA | EXPRESSION | MET | Cell Proliferation | Epithelial Cells - metabolism | Lymphokines - deficiency | Prognosis | Cancer-Associated Fibroblasts - metabolism | Stromal Cells - pathology | Humans | Middle Aged | Tumor Microenvironment | Neovascularization, Pathologic - pathology | Biomarkers, Tumor - metabolism | Lymphokines - metabolism | Estrogen Receptor alpha - metabolism | Female | Paracrine Communication | Signal Transduction | Mice, Inbred C57BL | Proportional Hazards Models | Platelet-Derived Growth Factor - deficiency | Treatment Outcome | Breast Neoplasms - blood supply | Platelet-Derived Growth Factor - metabolism | Animals | Breast Neoplasms - pathology | Fibrosis | Survival Analysis | Cell Line, Tumor | Care and treatment | Platelet-derived growth factor | Development and progression | Cellular signal transduction | Genetic aspects | Breast cancer | Health aspects | Animal models | Crosstalk | Stroma | Paracrine signalling | Pharmacology | Coevolution | Epithelium | Receptors | Fibroblasts | Breast | Sensitivity enhancement | Mammary gland | Growth factors | Tumors | Cancer | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Redox Biology, ISSN 2213-2317, 04/2015, Volume 4, Issue C, pp. 184 - 192
Cancer formation is a complex and highly regulated multi-step process which is highly dependent of its environment, from the tissue to the patient. This... 
Mitochondria | Antioxidant | Mitophagy | Autophagy | ROS | Cancer | KAPPA-B ACTIVATION | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL AUTOPHAGY | HYPOXIA | FIBROBLASTS | METABOLISM | STROMA COEVOLUTION | GROWTH | Neoplasms - metabolism | AMP-Activated Protein Kinases - metabolism | Autophagy-Related Proteins | Reactive Oxygen Species - metabolism | Humans | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Antineoplastic Agents - therapeutic use | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy-Related Protein-1 Homolog | Mitochondrial Degradation - genetics | Cysteine Endopeptidases - metabolism | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Autophagy - genetics | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Protein-Serine-Threonine Kinases - metabolism | Beclin-1 | Signal Transduction | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Lymphatic Metastasis | Mitochondria - metabolism | Mitochondria - pathology | Cell Transformation, Neoplastic - metabolism | Apoptosis Regulatory Proteins - metabolism | Neoplasms - drug therapy | Cysteine Endopeptidases - genetics | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | AMP-Activated Protein Kinases - genetics
Journal Article
Cell Cycle, ISSN 1538-4101, 08/2011, Volume 10, Issue 15, pp. 2521 - 2528
Journal Article
Oncogene, ISSN 0950-9232, 10/2013, Volume 33, Issue 41, pp. 4924 - 4931
DNA damage found in prostate cancer-associated fibroblasts (CAF) promotes tumor progression. In the absence of somatic mutations in CAF, epigenetic changes... 
DNA methylation | TGF-beta | Prostate cancer | IL-6 | Stromal coevolution | METHYLATION | TUMOR PROGRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | INDUCTION | FIBROBLASTS | CELL BIOLOGY | prostate cancer | THERAPY | ONCOLOGY | REACTIVE STROMA | GROWTH | GENETICS & HEREDITY | stromal coevolution | PROMOTER | TUMORIGENESIS | Receptors, Transforming Growth Factor beta - genetics | Oxidative Stress | Stromal Cells - pathology | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Male | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA Methylation | Prostatic Neoplasms - genetics | Receptor, Transforming Growth Factor-beta Type II | Interleukin-6 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Promoter Regions, Genetic | Prostatic Neoplasms - pathology | Glutathione S-Transferase pi - metabolism | Stromal Cells - metabolism | Protein-Serine-Threonine Kinases - genetics | Fibroblasts - pathology | Mice, SCID | Mice, Knockout | Animals | Receptors, Transforming Growth Factor beta - metabolism | DNA Repair | Mice | DNA Damage | Histones - metabolism | Transforming Growth Factor beta - metabolism | DNA damage | Oncology, Experimental | Genetic research | Development and progression | Genetic aspects | Research | Observations | Genetic regulation | Cancer | Epigenetics | Protein expression | stromal co-evolution
Journal Article
Molecular Genetics, Microbiology and Virology, ISSN 0891-4168, 7/2016, Volume 31, Issue 3, pp. 125 - 134
This review was devoted to the use of the universal component of tumoral stroma (fibroblast activation protein, FAP) as a target of the universal tumor... 
Life Sciences | cancer-associated fibroblasts | Microbiology | FAP | pancreas | stroma | Molecular Medicine | cancer | tumor microenvironment | DIPEPTIDYL-PEPTIDASE-IV | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | MICROBIOLOGY | OVARIAN-CANCER | MESENCHYMAL TRANSITION | PHASE-II TRIAL | PLATINUM RESISTANCE | STROMAL FIBROBLASTS | EXPRESSION | T-CELLS | Enzymes | Pancreatic cancer
Journal Article