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Journal Article
Cell Cycle, ISSN 1538-4101, 03/2012, Volume 11, Issue 6, pp. 1108 - 1117
We have recently proposed a new model of cancer metabolism to explain the role of aerobic glycolysis and L-lactate production in fueling tumor growth and... 
caveolin-1 | lactate shuttle | MCT4 | pseudohypoxia | monocarboxylic acid transporter | predictive biomarker | tumor stroma | SLC16A3 | metabolic coupling | oxidative stress | two compartment tumor metabolism | Metabolic coupling | Lactate shuttle | Caveolin-1, oxidative stress | SLC16A3, monocarboxylic acid transporter | Tumor stroma | Two compartment tumor metabolism | Pseudohypoxia | Predictive biomarker | MONOCARBOXYLATE TRANSPORTERS | AUTOPHAGY | PLASMA-MEMBRANE | FIBROBLASTS | CELL BIOLOGY | HIGH LACTATE LEVELS | OXIDATIVE MITOCHONDRIAL METABOLISM | CAVEOLIN-1 EXPRESSION | LACTIC-ACIDOSIS | HYDROGEN-PEROXIDE | two-compartment tumor metabolism | TUMOR MICROENVIRONMENT | Predictive Value of Tests | Oxidative Stress | Stromal Cells - pathology | Humans | Middle Aged | Breast Neoplasms - metabolism | Monocarboxylic Acid Transporters - metabolism | Neoplasm Grading | Muscle Proteins - metabolism | Immunoassay - methods | Adult | Female | Fibroblasts - metabolism | Epithelium - pathology | Epithelium - metabolism | Risk Assessment | Lactic Acid - metabolism | Risk Factors | Stromal Cells - metabolism | Kaplan-Meier Estimate | Oxidative Phosphorylation | Hydrogen Peroxide - metabolism | Caveolin 1 - metabolism | Breast Neoplasms - pathology | Staining and Labeling | Biomarkers | Glycolysis | Aged | Breast Neoplasms - diagnosis | Cohort Studies | Index Medicus
Journal Article
Cell Cycle, ISSN 1538-4101, 08/2013, Volume 12, Issue 16, pp. 2580 - 2597
Here, we developed a model system to evaluate the metabolic effects of oncogene(s) on the host microenvironment. A matched set of "normal" and oncogenically... 
wound healing | autophagy | RAS | glycolysis | cancer associated fibroblast | reverse Warburg effect | NFkB | oncogene | TOMM20 | metabolic parasite | senescence | caveolin-1 | MCT4 | field cancerization | inflammation | oncogenic stress | MCT1 | tumor microenvironment | response to injury | stromal biomarkers | oxidative stress | HaCaT | mitochondrial metabolism | Caveolin-1 | Oxidative stress | Reverse Warburg effect | Senescence | Wound healing | Tumor microenvironment | Oncogene | Stromal biomarkers | Inflammation | Cancer associated fibroblast | Autophagy | Oncogenic stress | Mitochondrial metabolism | Metabolic parasite | Response to injury | Glycolysis | Field cancerization | CELL BIOLOGY | BREAST-CANCER | SOIL HYPOTHESIS | FIBROTIC FOCUS | HYDROGEN-PEROXIDE | PROGNOSTIC-SIGNIFICANCE | CANCER-ASSOCIATED FIBROBLASTS | INVASIVE DUCTAL CARCINOMA | OXIDATIVE MITOCHONDRIAL METABOLISM | CAVEOLIN-1 EXPRESSION | PROTEIN EXPRESSION | Oncogenes - genetics | Reactive Oxygen Species - metabolism | Humans | Cell Cycle Proteins - metabolism | Oncogene Proteins - metabolism | Epithelial Cells | Tumor Microenvironment - physiology | Oncogenes - physiology | Drug Discovery | Caveolin 1 - metabolism | Stromal Cells | Mitochondrial Turnover - drug effects | Monocarboxylic Acid Transporters - metabolism | Flow Cytometry | Models, Biological | Acetylcysteine - pharmacology | Muscle Proteins - metabolism | Cell Line, Tumor | Glucose - metabolism | Antineoplastic Agents - pharmacology | Energy Metabolism - physiology | Gene Expression Regulation, Neoplastic - physiology | Index Medicus | Report
Journal Article
Cancer Medicine, ISSN 2045-7634, 09/2018, Volume 7, Issue 9, pp. 4690 - 4700
Monocarboxylate transporter‐4 ( MCT 4), a monocarboxylic acid transporter, demonstrates significantly increased expression in the majority of malignancies. We... 
NK cytotoxicity | MCT4 | NKG2D | NKG2DLs (H60) | lactate | MONOCARBOXYLATE TRANSPORTER 4 | ACID | TUMOR METABOLISM | MICROENVIRONMENT | ONCOLOGY | COLORECTAL-CANCER | POOR-PROGNOSIS | LYMPHOMA | STROMAL CELLS | EXPRESSION | Animal experimentation | Lactates | Killer cells | Breast cancer | Enzyme-linked immunosorbent assay | Cytotoxicity | Autophagy
Journal Article
Cell Cycle, ISSN 1538-4101, 04/2012, Volume 11, Issue 7, pp. 1445 - 1454
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, pp. e75154 - e75154
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 07/2019, Volume 453, pp. 95 - 106
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 05/2016, Volume 15, Issue 10, pp. 1376 - 1385
Journal Article
Cell Cycle, ISSN 1538-4101, 12/2012, Volume 11, Issue 23, pp. 4402 - 4413
Journal Article