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1. Full Text HIV-1–Associated Atherosclerosis: Unraveling the Missing Link
by Kearns, Alison and Gordon, Jennifer and Burdo, Tricia H and Qin, Xuebin
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2017, Volume 69, Issue 25, pp. 3084 - 3098
Cardiovascular disease, including atherosclerosis and atherosclerosis-associated complications, is an increasing cause of morbidity and mortality in human... 
macrophage | inflammation | caspase-1 | Tg26 transgenic mice | inflammasome | immune activation | INTIMA-MEDIA THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTIRETROVIRAL THERAPY | SUBCLINICAL ATHEROSCLEROSIS | ENDOPLASMIC-RETICULUM STRESS | HUMAN-IMMUNODEFICIENCY-VIRUS | HIV-INFECTED PATIENTS | UNFOLDED PROTEIN RESPONSE | T-CELL-ACTIVATION | CAROTID-ARTERY-DISEASE | HIV-1 | Morbidity - trends | Atherosclerosis - immunology | Survival Rate - trends | Global Health | HIV Infections - virology | Humans | Risk Factors | Atherosclerosis - epidemiology | Atherosclerosis - etiology | HIV Infections - immunology | HIV Infections - complications | Immunity, Cellular | Antiviral agents | Medical colleges | Neurosciences | Comorbidity | Low density lipoproteins | Mortality | HIV patients | Monkeys | T cells | HIV (Viruses) | Macrophages | Risk factors | Highly active antiretroviral therapy | Atherosclerosis | Genetic engineering | Epstein-Barr virus | Health aspects | Drug abuse | Therapy | Atherogenesis | Dyslipidemia | Viruses | Cardiovascular disease | Lymphocytes T | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Antiretroviral agents | Human immunodeficiency virus--HIV | Antiretroviral drugs | Complications | Therapeutic applications | Health risks | Risk analysis | Morbidity | Antiretroviral therapy | Arteriosclerosis | Cardiovascular diseases | Health risk assessment | Endoplasmic reticulum | Phagocytosis
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2. Full Text Antidepressant Use and Subclinical Measures of Atherosclerosis The Multi-Ethnic Study of Atherosclerosis
by Camacho, A and McClelland, RL and Delaney, JA and Allison, MA and Psaty, BM and Rifkin, DE and Rapp, SR and Szklo, M and Stein, MB and Criqui, MH
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, ISSN 0271-0749, 08/2016, Volume 36, Issue 4, pp. 340 - 346
Background: Antidepressants are commonly prescribed medications used in primary care. The cardiovascular safety profile of antidepressant medications, in terms... 
INTIMA-MEDIA THICKNESS | coronary artery calcium | RISK-FACTORS | MEDICATIONS | CORONARY EVENTS | PSYCHIATRY | MAJOR DEPRESSION | LATE-LIFE DEPRESSION | subclinical disease | PRIMARY-CARE | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | Multi-Ethnic Study of Atherosclerosis | antidepressant medication | HEALTH | POSTMENOPAUSAL WOMEN | Prospective Studies | Cross-Sectional Studies | United States - ethnology | Atherosclerosis - chemically induced | Humans | Middle Aged | Hispanic Americans | Male | Atherosclerosis - ethnology | European Continental Ancestry Group - ethnology | African Americans - ethnology | Aged, 80 and over | Atherosclerosis - diagnosis | Female | Aged | Antidepressive Agents - adverse effects | Asian Americans | sub-clinical disease
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3. Full Text Role of Coronary Artery Calcium Score of Zero and Other Negative Risk Markers for Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis (MESA)
by Blaha, Michael J and Cainzos-Achirica, Miguel and Greenland, Philip and McEvoy, John W and Blankstein, Ron and Budoff, Matthew J and Dardari, Zeina and Sibley, Christopher T and Burke, Gregory L and Kronmal, Richard A and Szklo, Moyses and Blumenthal, Roger S and Nasir, Khurram
Circulation, ISSN 0009-7322, 03/2016, Volume 133, Issue 9, pp. 849 - 858
BACKGROUND—Limited attention has been paid to negative cardiovascular disease (CVD) risk markers despite their potential to improve medical decision making. We... 
Biomarkers | risk assessment | cardiac imaging techniques | calcium | cardiovascular diseases | INTIMA-MEDIA THICKNESS | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | biomarkers | PREVENTION | SUBCLINICAL ATHEROSCLEROSIS | PREDICTION | HEART-DISEASE | RECLASSIFICATION | IMPACT | PERIPHERAL VASCULAR DISEASE | ASSOCIATION | Coronary Vessels - pathology | Prospective Studies | Cardiovascular Diseases - ethnology | Follow-Up Studies | Ethnic Groups - ethnology | Humans | Middle Aged | Risk Factors | Male | Atherosclerosis - ethnology | Biomarkers - blood | Coronary Vessels - metabolism | Atherosclerosis - blood | Calcium - blood | C-Reactive Protein - metabolism | Peptide Fragments - blood | Atherosclerosis - diagnosis | Cardiovascular Diseases - blood | Female | Aged | Natriuretic Peptide, Brain - blood | Cardiovascular Diseases - diagnosis | Cohort Studies | Research | Cardiovascular diseases | Biological markers | Risk factors | Coronary arteries | Cardiovascular disease | calcium score | marker | risk prediction
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4. Full Text Predicting Subclinical Atherosclerosis in Low-Risk Individuals: Ideal Cardiovascular Health Score and Fuster-BEWAT Score
by Fernández-Alvira, Juan Miguel and Fuster, Valentín and Pocock, Stuart and Sanz, Javier and Fernández-Friera, Leticia and Laclaustra, Martín and Fernández-Jiménez, Rodrigo and Mendiguren, José and Fernández-Ortiz, Antonio and Ibáñez, Borja and Bueno, Héctor
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2017, Volume 70, Issue 20, pp. 2463 - 2473
Background The ideal cardiovascular health score (ICHS) is recommended for use in primary prevention. Simpler tools not requiring laboratory tests, such as the... 
ideal cardiovascular health | cardiovascular risk | predictive tools | subclinical atherosclerosis | Fuster-BEWAT score | CARDIAC & CARDIOVASCULAR SYSTEMS | CORONARY-ARTERY CALCIUM | PESA | MARKERS | PREVALENCE | HEART | DISEASE RISK | ASSOCIATION | PROGRESSION | Morbidity - trends | Predictive Value of Tests | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Diagnostic Techniques, Cardiovascular | Male | Asymptomatic Diseases | Atherosclerosis - epidemiology | Spain - epidemiology | Atherosclerosis - diagnosis | Adult | Female | Health Status | Risk factors | Atherosclerosis | Calcification (ectopic) | Heart | Calcium | Laboratories | Cardiovascular disease | Family medical history | Arteries | Confidence intervals | Body mass index | Exercise | Aorta | Blood pressure | Plaques | Urine | Medical imaging | Statistical analysis | Middle age | Risk groups | Mortality | Coronary artery | Health risks | Laboratory tests | Nutrition research | Physical fitness | Tobacco | Diet | Arteriosclerosis | Coronary vessels | Lifestyles | Health risk assessment | Smoking | Veins & arteries
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5. Full Text The association of nonalcoholic fatty liver disease, obesity, and metabolic syndrome, with systemic inflammation and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA)
by Al Rifai, Mahmoud and Silverman, Michael G and Nasir, Khurram and Budoff, Matthew J and Blankstein, Ron and Szklo, Moyses and Katz, Ronit and Blumenthal, Roger S and Blaha, Michael J
Atherosclerosis, ISSN 0021-9150, 2015, Volume 239, Issue 2, pp. 629 - 633
Abstract Introduction We characterized the association of 3 metabolic conditions – obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) –... 
Cardiovascular | Obesity | Nonalcoholic fatty liver disease | Inflammation | Subclinical atherosclerosis | Metabolic syndrome | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | CORONARY-ARTERY CALCIUM | ENDOTHELIAL DYSFUNCTION | COMPUTED-TOMOGRAPHY | HEART-DISEASE | INSULIN-RESISTANCE | QUANTITATIVE ASSESSMENT | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HEPATIC STEATOSIS | RISK DEVELOPMENT | Multivariate Analysis | Predictive Value of Tests | United States - epidemiology | Prevalence | Humans | Middle Aged | Male | Non-alcoholic Fatty Liver Disease - ethnology | Tomography, X-Ray Computed | Asymptomatic Diseases | Inflammation - blood | Metabolic Syndrome - ethnology | Female | Obesity - diagnosis | Inflammation - diagnosis | C-Reactive Protein - analysis | Odds Ratio | Body Mass Index | Non-alcoholic Fatty Liver Disease - diagnostic imaging | Cross-Sectional Studies | Risk Factors | Inflammation Mediators - blood | Obesity - ethnology | Linear Models | Logistic Models | Biomarkers - blood | Coronary Artery Disease - ethnology | Coronary Angiography | Coronary Artery Disease - diagnostic imaging | Metabolic Syndrome - diagnosis | Sex Factors | Inflammation - ethnology | Aged | Prevention | Medical research | Fatty liver | Atherosclerosis | Medicine, Experimental | Heart diseases
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6. Full Text LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
by Mora, Samia and Szklo, Moyses and Otvos, James D and Greenland, Philip and Psaty, Bruce M and Goff, David C and O’Leary, Daniel H and Saad, Mohammed F and Tsai, Michael Y and Sharrett, A. Richey
Atherosclerosis, ISSN 0021-9150, 2006, Volume 192, Issue 1, pp. 211 - 217
Abstract Background Previous studies showing that smaller low-density lipoprotein (LDL) size is associated with greater atherosclerotic risk did not adequately... 
Cardiovascular | Magnetic resonance spectroscopy | Lipids | Lipoproteins | Subclinical atherosclerosis | Carotid arteries | INTIMA-MEDIA THICKNESS | lipids | CARDIAC & CARDIOVASCULAR SYSTEMS | SUSCEPTIBILITY | LOW-DENSITY-LIPOPROTEIN | SUBFRACTIONS | magnetic resonance spectroscopy | RISK | carotid arteries | ISCHEMIC-HEART-DISEASE | subclinical atherosclerosis | MAGNETIC-RESONANCE-SPECTROSCOPY | MEN | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | lipoproteins | CORONARY-ARTERY-DISEASE | Tunica Media - pathology | Lipoproteins, LDL - chemistry | Cross-Sectional Studies | Lipoproteins, LDL - classification | Humans | Middle Aged | Male | Carotid Artery Diseases - ethnology | Particle Size | Regression Analysis | Carotid Arteries - diagnostic imaging | Carotid Artery Diseases - diagnostic imaging | Tunica Intima - pathology | Carotid Artery Diseases - pathology | Carotid Artery Diseases - blood | Ultrasonography | Nuclear Magnetic Resonance, Biomolecular | Female | Aged | Carotid Arteries - pathology | Lipoproteins, LDL - blood | Cohort Studies | Prevention | Low density lipoproteins | Atherosclerosis | Blood lipids | Medicine, Preventive | Public health | Preventive health services
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7. Full Text From endothelial dysfunction to atherosclerosis
by Sitia, S and Tomasoni, L and Atzeni, F and Ambrosio, G and Cordiano, C and Catapano, A and Tramontana, S and Perticone, F and Naccarato, P and Camici, P and Picano, E and Cortigiani, L and Bevilacqua, M and Milazzo, L and Cusi, D and Barlassina, C and Sarzi-Puttini, P and Turiel, M
Autoimmunity Reviews, ISSN 1568-9972, 2010, Volume 9, Issue 12, pp. 830 - 834
Abstract It has recently emerged that endothelial dysfunction is an early step in the development of atherosclerosis and is mainly characterised by a reduction... 
Allergy and Immunology | Endothelial dysfunction | Arterial hypertension | Inflammation | Coronary microcirculation | Autoimmune diseases | Atherosclerosis | AUTOIMMUNE RHEUMATIC-DISEASES | STRESS ECHOCARDIOGRAPHY | ASYMMETRIC DIMETHYLARGININE | LOW-DENSITY-LIPOPROTEIN | SUBCLINICAL ATHEROSCLEROSIS | IMMUNOLOGY | PROGNOSTIC VALUE | NITRIC-OXIDE | WALL-MOTION CRITERIA | CORONARY FLOW RESERVE | ALPHA-ADDUCIN | Hypertension | Nitrogen oxide | Autoimmunity | Hyperglycemia | Development and progression | Insulin resistance | Diabetes | Blood lipids | Endothelium
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8. Full Text Coronary risk stratification, discrimination, and reclassification improvement based on quantification of Subclinical coronary atherosclerosis: The Heinz Nixdorf Recall study
by Erbel, Raimund and Mhlenkamp, Stefan and Moebus, Susanne and Schmermund, Axel and Lehmann, Nils and Stang, Andreas and Dragano, Nico and Grnemeyer, Dietrich and Seibel, Rainer and Klsch, Hagen and Brcker-Preuss, Martina and Mann, Klaus and Siegrist, Johannes and Jckel, Karl-Heinz and Heinz Nixdorf Recall Study Investi and Heinz Nixdorf Recall Study Investigative Group
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2010, Volume 56, Issue 17, pp. 1397 - 1406
Objectives The purpose of this study was to determine net reclassification improvement (NRI) and improved risk prediction based on coronary artery... 
risk factors | coronary artery calcification | cardiac death | subclinical atherosclerosis | reclassification | myocardial infarction | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | ARTERY CALCIUM SCORE | PREVALENCE | PROGNOSTIC VALUE | COMPUTED-TOMOGRAPHY | PREDICTION | BIOMARKERS | HEART-DISEASE | CARDIOVASCULAR RISK | Myocardial Infarction - diagnosis | Myocardial Infarction - mortality | Coronary Artery Disease - classification | Risk Assessment | Humans | Middle Aged | Risk Factors | Calcinosis - diagnostic imaging | Male | Tomography, X-Ray Computed | Coronary Angiography | Coronary Artery Disease - diagnostic imaging | Female | Aged | Cohort Studies | Heart rate | Heart attacks | Discrimination | Algorithms | Atherosclerosis | Biomarkers | Tomography | Cardiovascular disease | Diabetes | Health risk assessment | Kinases | Cholesterol
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9. Full Text Danger Signaling in Atherosclerosis
by Zimmer, Sebastian and Grebe, Alena and Latz, Eicke
Circulation Research, ISSN 0009-7330, 01/2015, Volume 116, Issue 2, pp. 323 - 340
All aspects of the pathogenesis of atherosclerosis are critically influenced by the inflammatory response in vascular plaques. Research in the field of innate... 
atherosclerosis | pattern recognition receptors | cardiovascular diseases | innate immunity | inflammation | DOUBLE-STRANDED-RNA | CARDIAC & CARDIOVASCULAR SYSTEMS | NLRP3 INFLAMMASOME ACTIVATION | TOLL-LIKE RECEPTOR-4 | INDUCIBLE GENE-I | MOBILITY GROUP BOX-1 | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | NF-KAPPA-B | SUBCLINICAL CORONARY ATHEROSCLEROSIS | PATTERN-RECOGNITION RECEPTORS | GLYCATION END-PRODUCTS | Atherosclerosis - etiology | Immunity, Innate - immunology | Signal Transduction - immunology | Animals | Atherosclerosis - immunology | Humans | Atherosclerosis - microbiology
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10. Full Text Subclinical Atherosclerosis Burden by 3D Ultrasound in Mid-Life: The PESA Study
by López-Melgar, Beatriz and Fernández-Friera, Leticia and Oliva, Belén and García-Ruiz, José Manuel and Peñalvo, José Luis and Gómez-Talavera, Sandra and Sánchez-González, Javier and Mendiguren, José María and Ibáñez, Borja and Fernández-Ortiz, Antonio and Sanz, Javier and Fuster, Valentín
Journal of the American College of Cardiology, ISSN 0735-1097, 07/2017, Volume 70, Issue 3, pp. 301 - 313
Background Detection of subclinical atherosclerosis improves risk prediction beyond cardiovascular risk factors (CVRFs) and risk scores, but quantification of... 
plaque volume | 3-dimensional ultrasound | carotid plaque | femoral plaque | subclinical atherosclerosis | INTIMA-MEDIA THICKNESS | CARDIAC & CARDIOVASCULAR SYSTEMS | CAROTID ATHEROSCLEROSIS | CORONARY | PREVALENCE | VASCULAR ULTRASOUND | DISEASE | ASSOCIATION | PROGRESSION | CARDIOVASCULAR RISK-FACTORS | Plaque, Atherosclerotic - diagnosis | Reproducibility of Results | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Male | Asymptomatic Diseases | Disease Progression | Carotid Arteries - diagnostic imaging | Femoral Artery - diagnostic imaging | Atherosclerosis - diagnosis | Adult | Female | Imaging, Three-Dimensional | Ultrasonography - methods | Development and progression | Analysis | Atherosclerosis | Hypertension | Middle age | Dyslipidemia | Health risks | Regression analysis | Risk analysis | Carotid arteries | Risk factors | Studies | Ultrasonic imaging | Arteriosclerosis | Cardiovascular diseases | Health risk assessment | Ultrasound | Age | Plaques
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11. Full Text Association of Airflow Limitation With Carotid Atherosclerosis in a Japanese Community　― The Hisayama Study
by Kudo, Kunihiro and Hata, Jun and Matsumoto, Koichiro and Shundo, Yuki and Fukuyama, Satoru and Inoue, Hiromasa and Kitazono, Takanari and Kiyohara, Yutaka and Ninomiya, Toshiharu and Nakanishi, Yoichi
Circulation Journal, ISSN 1346-9843, 2017, Volume 81, Issue 12, pp. 1846 - 1853
Background:There has been no large-scale observational study examining the association between chronic obstructive pulmonary disease (COPD) or airflow... 
Chronic obstructive pulmonary disease | Epidemiology | Atherosclerosis | Carotid intima-media thickness | Airflow limitation | INTIMA-MEDIA THICKNESS | LUNG | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | SUBCLINICAL ATHEROSCLEROSIS | SMOKING | OBSTRUCTIVE PULMONARY-DISEASE | INFLAMMATION | CARDIOVASCULAR-DISEASE | COPD | Spirometry | Asian Continental Ancestry Group | Age Factors | Carotid Intima-Media Thickness | Humans | Middle Aged | Risk Factors | Ultrasonography | Carotid Artery Diseases - physiopathology | Adult | Aged
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12. Full Text Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice
by Fuster, José J and MacLauchlan, Susan and Zuriaga, María A and Polackal, Maya N and Ostriker, Allison C and Chakraborty, Raja and Wu, Chia-Ling and Sano, Soichi and Muralidharan, Sujatha and Rius, Cristina and Vuong, Jacqueline and Jacob, Sophia and Muralidhar, Varsha and Robertson, Avril A. B and Cooper, Matthew A and Andrés, Vicente and Hirschi, Karen K and Martin, Kathleen A and Walsh, Kenneth
Science, ISSN 0036-8075, 02/2017, Volume 355, Issue 6327, pp. 842 - 847
Human aging is associated with an increased frequency of somatic mutations in hematopoietic cells. Several of these recurrent mutations, including those in the... 
STEM-CELLS | HOMEOSTASIS | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | MALIGNANCIES | SUBCLINICAL ATHEROSCLEROSIS | DIFFERENTIATION | PREVALENCE | MYELOID CANCERS | SOMATIC MUTATIONS | MOSAICISM | Receptors, LDL - genetics | Inflammasomes - metabolism | Plaque, Atherosclerotic - genetics | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Atherosclerosis - genetics | Mice, Inbred C57BL | Hematopoiesis - genetics | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | DNA-Binding Proteins - genetics | Macrophages | Animals | Mice | Mutation | Physiological aspects | Aging | Hematopoiesis | Health aspects | Low density lipoproteins | Atherosclerosis | Elderly people | Regulators | Cytokines | Cloning | Genes | Interleukin | Blood cells | Health risks | Cardiovascular disease | Blood | Hemopoiesis | Hemopoietic system | Rodents | Arteriosclerosis | Interleukin 1 | Epigenetics | Bone marrow | Mutations | Secretions | Heart diseases
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13. Full Text Hypothyroidism and Atherosclerosis
by Cappola, Anne R and Ladenson, Paul W
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2003, Volume 88, Issue 6, pp. 2438 - 2444
TOTAL HOMOCYSTEINE LEVELS | HEART-DISEASE | ENDOCRINOLOGY & METABOLISM | LOW-DENSITY-LIPOPROTEIN | CHOLESTERYL ESTER TRANSFER | SUBCLINICAL HYPOTHYROIDISM | CARDIOVASCULAR-DISEASE | THYROID REPLACEMENT THERAPY | L-THYROXINE THERAPY | TRANSLUMINAL CORONARY ANGIOPLASTY | VASCULAR SMOOTH-MUSCLE | Arteriosclerosis - etiology | Arteriosclerosis - surgery | Cardiovascular Diseases | Humans | Hypothyroidism - complications | Risk Factors | Hypothyroidism - drug therapy | Thyroid Hormones - adverse effects | Thyroid Hormones - therapeutic use
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14. Full Text Polypill Therapy, Subclinical Atherosclerosis, and Cardiovascular Events—Implications for the Use of Preventive Pharmacotherapy
by Bittencourt, Márcio Sommer, MD and Blaha, Michael J., MD, MPH and Blankstein, Ron, MD and Budoff, Matthew, MD and Vargas, Jose D., MD and Blumenthal, Roger S., MD and Agatston, Arthur S., MD and Nasir, Khurram, MD, MPH
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 63, Issue 5, pp. 434 - 443
Objectives This study examines whether the coronary artery calcium (CAC) score can be used to define the target population to treat with a polypill. Background... 
Cardiovascular | Internal Medicine | polypill | subclinical atherosclerosis | risk stratification | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | PREDICTION | ALL-CAUSE MORTALITY | INDIVIDUALS | CORONARY-ARTERY CALCIFICATION | DISEASE | CALCIUM | POPULATION-BASED COHORT | DOUBLE-BLIND | Sects | Usage | Drug therapy | Heart diseases | Public health | Atherosclerosis | Cardiovascular disease | Heart attacks | Cholesterol
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