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Acta Ophthalmologica, ISSN 1755-375X, 09/2017, Volume 95, Issue 6, pp. e443 - e452
PurposeTo compare the outcome after choroidal neovascular (CNV) membrane excision and retinal pigment epithelium (RPE) transplantation and make further... 
age‐related macular degeneration | subretinal haemorrhage | RPE | transplantation | autologous retinal pigment epithelium | monolayer sheet graft | choroidal neovascular membrane excision | Bruch's membrane complex graft | RPE–Bruch's membrane complex graft | autologous retinal pigment epithelium (RPE) transplantation | age-related macular degeneration | RPE monolayer sheet graft | CHOROID TRANSLOCATION | RPE-Bruch's membrane complex graft | VERTEPORFIN | HUMAN EYES | OPHTHALMOLOGY | SUBMACULAR SURGERY | INTRAVITREAL BEVACIZUMAB | RANIBIZUMAB | Bruch Membrane - transplantation | Choroidal Neovascularization - diagnosis | Retinal Pigment Epithelium - transplantation | Follow-Up Studies | Humans | Male | Transplantation, Autologous | Choroidal Neovascularization - surgery | Visual Acuity | Wet Macular Degeneration - diagnosis | Female | Aged | Retrospective Studies | Wet Macular Degeneration - surgery | Ophthalmologic Surgical Procedures - methods | Fundus Oculi | Fluorescein Angiography | Macular degeneration | Diabetic retinopathy | Medical research | Physiological aspects | Medicine, Experimental | Comparative analysis | Epithelium | Autografts | Retinopathy | Stability | Complications | Diabetes mellitus | Retina | Visual acuity | Transplantation | Patients | Hemorrhage | Grafting | Retinal pigment epithelium | Subgroups | Visual perception | Acuity | Detachment | Fixation | Grafts | Eye (anatomy) | Degeneration | Age | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
Journal Article
Stem Cells and Development, ISSN 1547-3287, 09/2019, Volume 28, Issue 17, pp. 1151 - 1166
To develop biological approaches to restore vision, we developed a method of transplanting stem cell-derived retinal tissue into the subretinal space of a... 
Original Research Reports | Index Medicus | large-eye animal models | synaptic connectivity | vision restoration | retinal organoids | human embryonic stem cells | subretinal transplantation
Journal Article
Regulatory Toxicology and Pharmacology, ISSN 0273-2300, 08/2019, Volume 106, pp. 7 - 14
This study aimed to determine the safety and tolerability of the subretinal injection of hESC-derived RPE cells at higher doses than the established clinical... 
Preclinical study | hESC-derived RPE cell | Minipig | Age-related macular degeneration | Subretinal injection | Macular degeneration | Immunohistochemistry | Viral antibodies | Medical colleges | Safety and security measures | Stem cells | Antibodies | Transplantation | Embryonic stem cells
Journal Article
Journal Article
Journal Article
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ISSN 0141-8130, 06/2019, Volume 130, pp. 220 - 228
Retinal pigment epithelium (RPE) plays an important role in maintaining normal function and visual function of the retina, and the degeneration of RPE causes... 
POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Gellan gum | CHOROIDAL NEOVASCULARIZATION | MECHANICAL-PROPERTIES | SUBRETINAL SPACE | CARRIERS | CULTURE | Polyethylene glycol | Biocompatibility | FABRICATION | Retinal pigment epithelial | Hydrogel | DIFFERENTIATION | CHEMISTRY, APPLIED | POLYMER SCAFFOLDS
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Journal Article
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Journal Article