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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 07/2018, Volume 366, Issue 1, pp. 136 - 144
Tachykinin neurokinin 2 (NK2) receptor agonists may have potential to alleviate clinical conditions associated with bladder and gastrointestinal underactivity... 
ANTAGONIST | TACHYKININS | PHARMACOLOGY & PHARMACY | COLON | MECHANISMS | BLADDER | SUBSTANCE-P | NEUROKININ-A
Journal Article
Immunological Reviews, ISSN 0105-2896, 03/2018, Volume 282, Issue 1, pp. 87 - 113
Summary Mast cells (MCs) are innate immune cells that are scattered in tissues throughout the organism being particularly abundant at sites exposed to the... 
CD63 | glucocorticoid receptor | CD151 | CD81 | neuropeptides | retinoic acid‐inducible gene‐I‐like receptors | alarmins | aryl hydrocarbon receptor | endothelin receptors | integrins | Fc receptor | PPAR | CD37 | vitamin D receptor | complement | nucleotide oligomerization domain‐like receptors | substance P | CD53 | IL‐1 | neurotensin | mast cell | free light chain | Toll‐like receptor | IL‐33 | sphingosine‐1 phosphate | CD9 | GPCR | CD48 | MAS‐related GPCR | ATP | pattern recognition receptor | nucleotide oligomerization domain-like receptors | MAS-related GPCR | Toll-like receptor | sphingosine-1 phosphate | IL-1 | IL-33 | retinoic acid-inducible gene-I-like receptors | IMMUNOLOGY | ARYL-HYDROCARBON RECEPTOR | TOLL-LIKE RECEPTORS | SUBSTANCE-P | FC-EPSILON-RI | DIFFERENTIAL EXPRESSION | CONTROLS ALLERGIC SENSITIZATION | HISTAMINE-RELEASE | FREE LIGHT-CHAINS | I-LIKE RECEPTORS | VASOACTIVE INTESTINAL POLYPEPTIDE | Receptors, Pattern Recognition - metabolism | Animals | Cytokines - metabolism | Humans | Immunoglobulin E - metabolism | Receptors, Fc - metabolism | Cellular Microenvironment | Mast Cells - physiology | Immunity, Innate | Receptors, Cytoplasmic and Nuclear - metabolism | Fc receptors | Vitamin D | Sphingosine | Immunoglobulin E | Calcifediol | Neuropeptides | Alfacalcidol | Integrins | Immunoglobulins | Cytokines | Mucosa | Effector cells | Inflammatory response | Activation | Inflammation | Hormones | Pattern recognition | Tissues | Nuclear receptors | Allergies | Receptors | Cell activation | Skin | Toxins | Mast cells | Chemokines | Immune system | Life Sciences | Immunology
Journal Article
by He, SQ and Zhang, ZN and Guan, JS and Liu, HR and Zhao, B and Wang, HB and Li, QA and Yang, H and Luo, J and Li, ZY and Wang, QO and Lu, YJ and Bao, L and Zhang, X
NEURON, ISSN 0896-6273, 01/2011, Volume 69, Issue 1, pp. 120 - 131
delta-opioid receptors (DORs) form heteromers with mu-opioid receptors (MORs) and negatively regulate MOR-mediated spinal analgesia. However, the underlying... 
RAT SPINAL-CORD | KNOCK-OUT MICE | TOLERANCE | PHYSICAL-DEPENDENCE | DOWN-REGULATION | DORSAL-ROOT GANGLIA | PROTEIN-COUPLED RECEPTORS | MORPHINE ANALGESIA | SUBSTANCE-P | NEUROSCIENCES | NOXIOUS THERMAL STIMULI
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2004, Volume 24, Issue 18, pp. 4300 - 4312
Inflammatory proteases (mast cell tryptase and trypsins) cleave protease-activated receptor 2 (PAR(2)) on spinal afferent neurons and cause persistent... 
Protein kinase C | Inflammation | TRPV1 | Substance P | Hyperalgesia | Protease-activated receptors | protease-activated receptors | THERMAL HYPERALGESIA | ROOT GANGLION NEURONS | PAIN PATHWAY | RAT SENSORY NEURONS | NEUROSCIENCES | inflammation | SIGNALING PATHWAY | KINASE-C ACTIVATION | MYENTERIC NEURONS | MOLECULAR-CLONING | hyperalgesia | substance P | THROMBIN RECEPTOR | protein kinase C | MAST-CELL TRYPTASE | Enzyme Activators - pharmacology | Hyperalgesia - chemically induced | Spinal Cord - drug effects | Spinal Cord - metabolism | Calcium - metabolism | Capsaicin - pharmacology | Receptors, Drug - genetics | Humans | Receptor, PAR-2 - metabolism | Type C Phospholipases - metabolism | Male | Neurons - cytology | RNA, Messenger - metabolism | Receptors, Drug - agonists | Type C Phospholipases - antagonists & inhibitors | Kidney - metabolism | Protein Kinase C - metabolism | Neurons - metabolism | Calcitonin Gene-Related Peptide - metabolism | Neurons - drug effects | Receptor, PAR-2 - genetics | Hyperalgesia - metabolism | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Kidney - cytology | Protein Kinase C - antagonists & inhibitors | Rats, Sprague-Dawley | Receptors, Drug - metabolism | Mice, Knockout | Animals | Receptor, PAR-2 - agonists | Substance P - metabolism | Mice | Cellular | Molecular
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