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SCIENCE, ISSN 0036-8075, 10/2017, Volume 358, Issue 6362, pp. 518 - 518
Proteases of the malaria parasite Plasmodium falciparum have long been investigated as drug targets. The P. falciparum genome encodes 10 aspartic proteases... 
ERYTHROCYTES | PLASMODIUM-FALCIPARUM | HOST-CELL | MULTIDISCIPLINARY SCIENCES | CELL INVASION | SERINE-PROTEASE | INHIBITORS | SUBTILISIN-LIKE PROTEASE-1 | PROTEINS | IDENTIFICATION | EXPRESSION
Journal Article
Cellular Microbiology, ISSN 1462-5814, 10/2008, Volume 10, Issue 10, pp. 1925 - 1934
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 03/2008, Volume 4, Issue 3, pp. 203 - 213
Newly replicated Plasmodium falciparum parasites escape from host erythrocytes through a tightly regulated process that is mediated by multiple classes of... 
CYSTEINE PROTEASE | PARASITOPHOROUS VACUOLE | VINYL SULFONES | STREPTOLYSIN-O | MEROZOITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL INVASION | I CATHEPSIN-C | SERINE-PROTEASE | SUBTILISIN-LIKE PROTEASE-1 | ANTIGEN | Cysteine Endopeptidases - chemistry | Plasmodium falciparum - enzymology | Parasitic Sensitivity Tests | Protozoan Proteins - antagonists & inhibitors | Stereoisomerism | Humans | Molecular Conformation | Subtilisins - chemistry | Plasmodium falciparum - drug effects | Cysteine Endopeptidases - drug effects | Sulfones - pharmacology | Serine Endopeptidases - drug effects | Dose-Response Relationship, Drug | Antigens, Protozoan - metabolism | Protease Inhibitors - pharmacology | Antigens, Protozoan - drug effects | Cysteine Endopeptidases - metabolism | Protozoan Proteins - metabolism | Isocoumarins - pharmacology | Sulfones - chemistry | Malaria, Falciparum - metabolism | Protozoan Proteins - chemistry | Subtilisins - metabolism | Plasmodium falciparum - physiology | Peptides - chemistry | Protease Inhibitors - chemistry | Serine Endopeptidases - chemistry | Subtilisins - antagonists & inhibitors | Peptides - pharmacology | Host-Parasite Interactions - drug effects | Malaria, Falciparum - parasitology | Animals | Small Molecule Libraries | Erythrocytes - metabolism | Serine Endopeptidases - metabolism | Erythrocytes - parasitology | Isocoumarins - chemistry | Biochemistry | Biomedical research | Parasites | Malaria | Proteases | Erythrocytes
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2005, Volume 1, Issue 3, pp. 0241 - 0251
Proteolytic shedding of surface proteins during invasion by apicomplexan parasites is a widespread phenomenon, thought to represent a mechanism by which the... 
APICAL MEMBRANE ANTIGEN-1 | PLASMODIUM-FALCIPARUM MEROZOITES | HOST-CELL INVASION | APICOMPLEXAN PARASITES | CRYSTAL-STRUCTURE | MICRONEME PROTEINS | MICROBIOLOGY | ACTIN-FILAMENTS | SUBTILISIN-LIKE PROTEASE-1 | ERYTHROCYTE INVASION | VIROLOGY | TOXOPLASMA-GONDII | PARASITOLOGY | Proteins | Parasites | Malaria | Erythrocytes | Plasmodium | Parasitology | Biochemistry | Microbiology
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2009, Volume 28, Issue 6, pp. 725 - 735
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2012, Volume 287, Issue 45, pp. 37949 - 37963
Journal Article
Journal Article
Chemistry of Heterocyclic Compounds, ISSN 0009-3122, 01/2015, Volume 50, Issue 10, pp. 1456 - 1462
2,3-Bis(phenylamino)quinoxalines have been identified as a novel class of malarial protease PfSUB1 inhibitors by screening of Malaria Box compounds. The... 
inhibitors | PfSUB1 protease | quinoxaline | Malaria Box | malaria | PLASMODIUM-FALCIPARUM | CHEMISTRY, ORGANIC | DRUG-RESISTANT MALARIA | SUBTILISIN-LIKE PROTEASE-1 | PARASITE | Malaria | Proteases
Journal Article