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Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 12/2017, Volume 21, Issue 12, pp. 3540 - 3551
Endothelial injury or dysfunction is an early event in the pathogenesis of atherosclerosis. Epidemiological and animal studies have shown that 2, 3, 7,... 
apoptosis | EP3 | Bcl‐2 | dioxin | p38 MAPK | endothelial cell | Bcl-2 | MEDICINE, RESEARCH & EXPERIMENTAL | TCDD-INDUCED APOPTOSIS | ATHEROSCLEROSIS | RECEPTOR | PROLIFERATION | INCREASES APOPTOSIS | 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN | CELL BIOLOGY | SIGNALING PATHWAY | GENE-EXPRESSION | DYSFUNCTION | E-DEFICIENT MICE | RNA, Small Interfering - genetics | Human Umbilical Vein Endothelial Cells - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Endothelium, Vascular - drug effects | Re-Epithelialization - physiology | Dose-Response Relationship, Drug | Femoral Artery - injuries | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cyclooxygenase 2 - genetics | Caspase 3 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Environmental Pollutants - toxicity | Dinoprostone - agonists | Receptors, Prostaglandin E, EP3 Subtype - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Receptors, Prostaglandin E, EP3 Subtype - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Mice, Knockout | Dinoprostone - metabolism | Animals | Endothelium, Vascular - metabolism | Receptors, Prostaglandin E, EP3 Subtype - antagonists & inhibitors | Cyclooxygenase 2 - metabolism | Polychlorinated Dibenzodioxins - toxicity | Endothelium, Vascular - pathology | Human Umbilical Vein Endothelial Cells - pathology | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA, Small Interfering - metabolism | Herbicides | COX-2 inhibitors | Enzymes | Dioxin | Prostaglandins E | Atherosclerosis | Genetic engineering | Epidemiology | Apoptosis | Endothelium | Phosphorylation | Femur | Femoral artery | Bcl-2 protein | Pathogenesis | Prostaglandin E2 | TCDD | Dioxins | Activation | Caspase-3 | Cell activation | Rodents | Inhibition | Heart diseases | Injuries | Caspase | MAP kinase | Pharmacology | Exposure | Morbidity | Endothelial cells | Gene silencing | Cyclooxygenase-1 | Arteriosclerosis | Cyclooxygenase-2 | Cardiovascular diseases | Umbilical vein | Original
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2016, Volume 26, Issue 11, pp. 2670 - 2675
Journal Article
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 485, Issue 2, pp. 535 - 541
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 12/2005, Volume 22, Issue 12, pp. 3137 - 3146
Fever is induced by a neuronal mechanism in the brain. Prostaglandin (PG) E2 acts as a pyrogenic mediator in the preoptic area (POA) probably through the EP3... 
hyperthermia | stress response | thermoregulation | sympathetic nervous system | cardiovascular regulation | Thermoregulation | Cardiovascular regulation | Stress response | Sympathetic nervous system | Hyperthermia | AMINO-ACID RECEPTORS | PERIAQUEDUCTAL GRAY | BROWN ADIPOSE-TISSUE | NEUROSCIENCES | THERMOREGULATORY FUNCTIONS | NONSHIVERING THERMOGENESIS | MEDULLARY RAPHE | SYMPATHETIC PREMOTOR NEURONS | EVOKED THERMOGENESIS | BRAIN ENDOTHELIAL-CELLS | RAPHE PALLIDUS | Muscimol - pharmacology | Rats, Wistar | Sympathetic Nervous System - drug effects | gamma-Aminobutyric Acid - metabolism | Male | Neural Pathways - physiology | Preoptic Area - cytology | Heart Rate - drug effects | Transfection - methods | Body Temperature Regulation - drug effects | Blood Pressure - drug effects | Blood Pressure - physiology | Neurons - metabolism | Pyrogens - pharmacology | Neurons - drug effects | Neural Pathways - immunology | Dinoprostone - pharmacology | Green Fluorescent Proteins - metabolism | Body Temperature Regulation - physiology | Cholera Toxin - metabolism | Dorsomedial Hypothalamic Nucleus - cytology | Adipose Tissue, Brown - physiology | Rats | Functional Laterality | Dorsomedial Hypothalamic Nucleus - metabolism | Rats, Sprague-Dawley | Receptors, Prostaglandin E, EP3 Subtype | Animals | Cell Count - methods | GABA Agonists - pharmacology | Neural Pathways - cytology | Adipose Tissue, Brown - drug effects | Models, Neurological | Receptors, Prostaglandin E - metabolism
Journal Article