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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019, Volume 519, Issue 1, pp. 192 - 197
Type II diabetes is a metabolic disease that has affected 460 million people around the globe and become a heavy burden on health care system. Diabetic... 
Type II diabetes | MicroRNA | Sucrase-isomaltase | miR-26
Journal Article
World Chinese Journal of Digestology, ISSN 1009-3079, 05/2017, Volume 25, Issue 15, pp. 1345 - 1351
Journal Article
Voprosy Detskoi Dietologii, ISSN 1727-5784, 2018, Volume 16, Issue 5, pp. 39 - 43
Journal Article
06/2010
Human maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) are the small-intestinal glucosidases responsible for catalyzing the last glucose-releasing step... 
X-ray crystallography | sucrase isomaltase | starch digestion | Type 2 diabetes | 0487 | 0760 | maltase glucoamylase | alpha-glucosidase inhibitors | glycoside hydrolases
Dissertation
by Husein and Wanes and Marten and Zimmer and Naim
Nutrients, ISSN 2072-6643, 09/2019, Volume 11, Issue 10, p. 2290
Congenital sucrase-isomaltase deficiency (CSID) is an autosomal recessive disorder of carbohydrate maldigestion and malabsorption caused by mutations in the... 
congenital sucrase-isomaltase deficiency | intestinal brush border membrane | heterozygote | compound heterozygote | protein trafficking phenotypes | homozygote
Journal Article
Gastroenterology and Hepatology, ISSN 1554-7914, 01/2018, Volume 14, Issue 1, pp. 26 - 32
Patients with a disaccharidase deficiency typically present with abdominal discomfort and often with diarrhea. However, disaccharidase deficiency is often... 
Disaccharidase deficiency | Lactase deficiency | Physician variability | Sucrase-isomaltase deficiency | lactase deficiency | disaccharidase deficiency | physician variability | Column
Journal Article
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, ISSN 0277-2116, 06/2018, Volume 66, pp. S61 - S64
Background and Hypotheses: Human starch digestion is a multienzyme process involving 6 different enzymes: salivary and pancreatic a-amylase; sucrase and... 
congenital sucrase-isomaltase deficiency | NUTRITION & DIETETICS | food starch | digestion | PEDIATRICS | glucose production | GASTROENTEROLOGY & HEPATOLOGY | STARCH DIGESTION
Journal Article
Journal of the Academy of Nutrition and Dietetics, ISSN 2212-2672, 03/2018, Volume 118, Issue 3, pp. 440 - 447
Sucrose-isomaltase deficiency (SID) remains underdiagnosed. Absent or reduced enzyme activity promotes diarrhea, abdominal bloating, and flatulence from... 
Genetic sucrase-isomaltase deficiency | Sucrose intolerance | Maltose | Sucrose | Starch | NUTRITION & DIETETICS | MULTIPLE-PASS METHOD | VALIDATION | RECALL
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 08/2018, Volume 113, Issue 8, pp. 1254 - 1254
Journal Article
CELL DEATH AND DIFFERENTIATION, ISSN 1350-9047, 12/2017, Volume 24, Issue 12, pp. 2173 - 2186
On the basis of phylogenetic analyses, we uncovered a variant of the CDX2 homeobox gene, a major regulator of the development and homeostasis of the gut... 
COLON-CANCER CELLS | STEM-CELLS | MUTANT MICE | TRANSCRIPTION FACTOR CDX2 | POOR-PROGNOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUCRASE-ISOMALTASE | DIFFERENTIATION | BETA-CATENIN | EXPRESSION | CARCINOMA | CELL BIOLOGY
Journal Article
CARBOHYDRATE POLYMERS, ISSN 0144-8617, 03/2015, Volume 117, pp. 192 - 200
In vitro hydrolysis assays are a key tool in understanding differences in rate and extent of digestion of starchy foods. They offer a greater degree of... 
GLYCEMIC INDEX | POLYMER SCIENCE | Starch | PLANT FOODS | Amyloglucosidase | CEREAL PRODUCTS | CHEMISTRY, ORGANIC | SMALL-INTESTINE | Kinetic analysis | KINETIC EVIDENCE | MAIZE STARCH | RAPIDLY AVAILABLE GLUCOSE | Alpha amylase | PANCREATIC ALPHA-AMYLASE | RESISTANT STARCH | SUCRASE-ISOMALTASE | In vitro digestion | CHEMISTRY, APPLIED | Hydrolysis | Amylases
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 34, pp. 6250 - 6261
Four new alpha-glucosidase inhibitors have been synthesised through 5-8 synthetic steps from a common synthetic intermediate obtained through a recently... 
MALTASE-GLUCOAMYLASE | CHEMISTRY, ORGANIC | SUCRASE-ISOMALTASE | TRIACETOXYBOROHYDRIDE | TYPE-2 DIABETES-MELLITUS | DERIVATIVES | ORAL ANTIDIABETIC AGENTS | Hybrids | Inhibitors | Intestine | Miglitol | Glycosidases | Diastereoisomers | Homology | Glucosidase
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 06/2018, Volume 66 Suppl 3, pp. S11 - S13
OBJECTIVES:Maltase-glucoamylase and sucrase-isomaltase are enzymes in the brush-border membrane of the small intestinal lumen responsible for the breakdown of... 
protein structure | sucrase-isomaltase | x-ray crystallography | enzyme specificity | SUBSTRATE-SPECIFICITY | NUTRITION & DIETETICS | INHIBITION | PROTEIN | PEDIATRICS | GASTROENTEROLOGY & HEPATOLOGY | STARCH DIGESTION | maltase-glucoamylase
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 06/2018, Volume 66 Suppl 3, Issue Suppl 3, pp. S61 - S64
BACKGROUND AND HYPOTHESES:Human starch digestion is a multienzyme process involving 6 different enzymessalivary and pancreatic α-amylase; sucrase and... 
Usage | Analysis | Medical tests | Genetic aspects | Children | Research | Pediatric research | Diseases | digestion | glucose production | Congenital Sucrase-isomaltase Deficiency (CSID) | food starch
Journal Article
FASEB Journal, ISSN 0892-6638, 07/2018, Volume 32, Issue 7, pp. 3903 - 3911
Dietary starch is finally converted to glucose for absorption by the small intestine mucosal -glucosidases (sucrase-isomaltase [SI] and maltase-glucoamylase),... 
Carbohydrates | Glycosylation | Maltose | Gut epithelium | carbohydrates | MALTASE-GLUCOAMYLASE | DIFFERENTIAL EXPRESSION | LACTASE-PHLORHIZIN HYDROLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | gut epithelium | glycosylation | SUCRASE-ISOMALTASE COMPLEX | CELL BIOLOGY | maltose | DIGESTION | GLUCOSE | AMINOPEPTIDASE N | BIOLOGY | TASTE RECEPTORS | CACO-2 CELLS
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24585
Gastrointestinal disturbances are commonly reported in children with autism, complicate clinical management, and may contribute to behavioral impairment.... 
INFLAMMATORY-BOWEL-DISEASE | COLONIC MICROBIOTA | REGRESSIVE AUTISM | BIOLOGY | SPECTRUM DISORDERS | ISOMALTASE GENE-EXPRESSION | SUCRASE-ISOMALTASE | DIETARY INTERVENTION | GUT MICROBIOTA | MICROBIAL COMMUNITY | VIRAL-INFECTION | Metagenomics | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Autistic Disorder - physiopathology | Autistic Disorder - metabolism | Gastrointestinal Diseases - physiopathology | Humans | Transcriptome | Carbohydrate Metabolism - genetics | Child, Preschool | Ileum - metabolism | Infant | Male | Clostridium - isolation & purification | RNA, Messenger - metabolism | Gastrointestinal Diseases - microbiology | Digestion - genetics | Food Hypersensitivity - microbiology | Autistic Disorder - microbiology | Time Factors | Membrane Transport Proteins - genetics | RNA, Bacterial - genetics | Female | Biological Transport - genetics | Food Hypersensitivity - genetics | Comorbidity | RNA, Messenger - genetics | Clostridium - physiology | Gastrointestinal Diseases - complications | Clostridium - genetics | Intestinal Mucosa - microbiology | Food Hypersensitivity - complications | Gastrointestinal Diseases - metabolism | RNA, Ribosomal, 16S - genetics | Autistic Disorder - complications | Intestinal Mucosa - pathology | Surveys | Autism | Enzymes | Microbiota (Symbiotic organisms) | Analysis | Genes | Gastrointestinal diseases | Children | Gene expression | Sugars | Monosaccharides | Diseases | Hexose | Dysbacteriosis | Mucosa | Impairment | Genomes | Infections | CDX2 protein | Vaccines | Enzymatic activity | Neurodegeneration | Intestine | Rodents | Measles | Phylogenetics | Bacteria | Community structure | Carbohydrates | Immunoglobulins | Cytokines | Digestion | Asthma | Inflammatory bowel disease | Probiotics | Enterocytes | Diet | Disturbances | Transport | Viral infections
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 11/2018, Volume 315, Issue 5, pp. G762 - G771
Crohn's disease (CD) is a chronic, relapsing. inflammatory disease that is often associated with malnutrition because of inflammation in the small intestine.... 
Inflammatory bowel diseases | dependent glucose transporter 1 | Autotaxin | exchanger 3 | CELLS | PHYSIOLOGY | Na+-dependent glucose transporter 1 | inflammatory bowel diseases | CROHNS-DISEASE | autotaxin | Na+/H+ exchanger 3 | NHE3 | MURINE MODEL | ACID RECEPTOR 1 | ILEITIS | LYSOPHOSPHATIDIC ACID | SUCRASE-ISOMALTASE | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | BINDING
Journal Article
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