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1. Full Text An attempt for fast separation of enantiomers in nano‐liquid chromatography and capillary electrochromatography
by D'Orazio, Giovanni and Kakava, Rusudan and Volonterio, Alessandro and Fanali, Salvatore and Chankvetadze, Bezhan
Electrophoresis, ISSN 0173-0835, 08/2017, Volume 38, Issue 15, pp. 1932 - 1938
CEC | Sulfoxides | Fast enantioseparation | Chiral | Nano‐LC | Nano-LC | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Sulfoxides - chemistry | Models, Chemical | Time Factors | Nanotechnology - methods | Stereoisomerism | Sulfoxides - analysis | Sulfoxides - isolation & purification | Capillary Electrochromatography - methods | Chromatography, Liquid - methods | Enantiomers | Analysis | Liquid chromatography | Separation | Barriers | Scientific apparatus & instruments | Electrochromatography | Index Medicus
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2. Full Text Development of Chiral Sulfoxide Ligands for Asymmetric Catalysis
by Trost, Barry M and Rao, Meera
Angewandte Chemie (International ed.), ISSN 1433-7851, 04/2015, Volume 54, Issue 17, pp. 5026 - 5043
asymmetric synthesis | homogeneous catalysis | chiral ligands | chiral sulfoxides | transition metals | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Alkenes - chemistry | Sulfoxides - chemistry | Metals - chemistry | Stereoisomerism | Ligands | Catalysis | Cycloaddition Reaction | Alkylation | Synthesis | Enantiomers | Organosulfur compounds | Organic compounds | Index Medicus | Descriptions | Asymmetry | Chirality | Strategy | Sulfur | Bonding
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3. Full Text Synthesis of Axially Chiral Biaryls through Sulfoxide‐Directed Asymmetric Mild CH Activation and Dynamic Kinetic Resolution
by Hazra, Chinmoy Kumar and Dherbassy, Quentin and Wencel‐Delord, Joanna and Colobert, Françoise
Angewandte Chemie (International ed.), ISSN 1433-7851, 12/2014, Volume 53, Issue 50, pp. 13871 - 13875
CH activation | atroposelectivity | asymmetric synthesis | sulfoxides | dynamic kinetic resolution | Sulfoxides | Dynamic kinetic resolution | Asymmetric synthesis | C- H activation | Atroposelectivity | Sulfoxides - chemistry | Kinetics | Stereoisomerism | Hydrogen - chemistry | Carbon - chemistry | Index Medicus | Synthesis | Pathways | Asymmetry | Dynamics | Isomerization | Strategy | Activation | Transformations | Conversion | Organic chemistry | Chemical Sciences | Catalysis
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4. Full Text Metal-free oxidative coupling of alkyl chlorides with thiols: An efficient access to sulfoxides
by Liu, Qian and Zhao, Xiaoqian and Xu, Feng and Li, Gaoqiang
Tetrahedron letters, ISSN 0040-4039, 02/2020, Volume 61, Issue 7, p. 151492
Sulfoxides | Oxidation | Metal-free | Coupling
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5. Full Text A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent
by Jeany M. Rademaker-Lakhai and Desiree van den Bongard and Dick Pluim and Jos H. Beijnen and Jan H. M. Schellens
Clinical cancer research, ISSN 1078-0432, 06/2004, Volume 10, Issue 11, pp. 3717 - 3727
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Models, Chemical | Area Under Curve | Dimethyl Sulfoxide - chemistry | Humans | Middle Aged | Dimethyl Sulfoxide - pharmacology | Male | Antineoplastic Agents - therapeutic use | Ruthenium - chemistry | Dose-Response Relationship, Drug | DNA Adducts | Time Factors | Antineoplastic Agents - adverse effects | Organometallic Compounds - therapeutic use | Adult | Female | Antineoplastic Agents - pharmacology | Dimethyl Sulfoxide - therapeutic use | Dimethyl Sulfoxide - adverse effects | Organometallic Compounds - adverse effects | Treatment Outcome | Maximum Tolerated Dose | Aged | Dimethyl Sulfoxide - analogs & derivatives | Organometallic Compounds - pharmacology | Index Medicus
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6. Full Text Development of a liquid chromatography/tandem‐mass spectrometry assay for the simultaneous determination of teneligliptin and its active metabolite teneligliptin sulfoxide in human plasma
by Park, Jin‐Woo and Kim, Kyoung‐Ah and Park, Ji‐Young
Biomedical chromatography, ISSN 0269-3879, 02/2020, Volume 34, Issue 2, pp. e4721 - n/a
teneligliptin sulfoxide | LC‐MS/MS | teneligliptin | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Pharmacology & Pharmacy | Chemistry, Analytical | Science & Technology | Sulfoxides - blood | Limit of Detection | Reproducibility of Results | Thiazolidines - metabolism | Thiazolidines - pharmacokinetics | Drug Stability | Humans | Sulfoxides - pharmacokinetics | Linear Models | Pyrazoles - metabolism | Thiazolidines - blood | Sulfoxides - chemistry | Pyrazoles - chemistry | Pyrazoles - blood | Sulfoxides - metabolism | Chromatography, Liquid - methods | Pyrazoles - pharmacokinetics | Tandem Mass Spectrometry - methods | Thiazolidines - chemistry | Index Medicus
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7. Full Text BAY 1000394, a novel cyclin-dependent kinase inhibitor, with potent antitumor activity in mono- and in combination treatment upon oral application
by Siemeister, Gerhard and Lücking, Ulrich and Wengner, Antje M and Lienau, Philip and Steinke, Wolfram and Schatz, Christoph and Mumberg, Dominik and Ziegelbauer, Karl
Molecular cancer therapeutics, ISSN 1535-7163, 10/2012, Volume 11, Issue 10, pp. 2265 - 2273
Life Sciences & Biomedicine | Oncology | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cyclin-Dependent Kinases - metabolism | Antineoplastic Combined Chemotherapy Protocols - chemistry | Humans | Sulfoxides - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Agents - administration & dosage | Pyrimidines - chemistry | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Sulfoxides - administration & dosage | Protein Kinase Inhibitors - chemistry | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Cyclin-Dependent Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Protein Kinase Inhibitors - pharmacokinetics | Sulfoxides - pharmacology | Administration, Oral | Pyrimidines - administration & dosage | Retinoblastoma Protein - metabolism | Etoposide - pharmacology | Rats | Treatment Outcome | Cisplatin - pharmacology | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Xenograft Model Antitumor Assays | Protein Kinase Inhibitors - administration & dosage | Sulfoxides - chemistry | Animals | Mice, Nude | Pyrimidines - pharmacokinetics | Mice | Protein Kinase Inhibitors - pharmacology | Cell Cycle - drug effects | Index Medicus
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8. Full Text Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
by Leijen, Suzanne and Burgers, Sjaak A and Baas, Paul and Pluim, Dick and Tibben, Matthijs and van Werkhoven, Erik and Alessio, Enzo and Sava, Gianni and Beijnen, Jos H and Schellens, Jan H. M
Investigational new drugs, ISSN 0167-6997, 2015, Volume 33, Issue 1, pp. 201 - 214
NAMI-A | Ruthenium | Phase I | Medicine & Public Health | Gemcitabine | Non-small cell lung cancer | Oncology | Phase II | Pharmacology/Toxicology | Clinical study | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Ruthenium - administration & dosage | Deoxycytidine - pharmacokinetics | Ruthenium - adverse effects | Adult | Deoxycytidine - adverse effects | Dimethyl Sulfoxide - administration & dosage | Female | Ruthenium - blood | Dimethyl Sulfoxide - adverse effects | Organometallic Compounds - adverse effects | Deoxycytidine - administration & dosage | Carcinoma, Non-Small-Cell Lung - metabolism | Organometallic Compounds - pharmacokinetics | Treatment Outcome | Ruthenium - pharmacokinetics | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Dimethyl Sulfoxide - analogs & derivatives | Deoxycytidine - analogs & derivatives | Dimethyl Sulfoxide - pharmacokinetics | Organometallic Compounds - administration & dosage | Complications and side effects | Dosage and administration | Research | Lung cancer, Non-small cell | Drug therapy | Studies | Clinical trials | Lung cancer | Pharmaceutical sciences | Clinical outcomes | Index Medicus
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9. Full Text Chemoenzymatic Deracemization of Chiral Sulfoxides
by Nosek, Vladimír and Míšek, Jiří
Angewandte Chemie (International ed.), ISSN 1433-7851, 07/2018, Volume 57, Issue 31, pp. 9849 - 9852
deracemization | oxidoreductases | chiral sulfoxides | biocatalysis | biphasic reactions | Enzymes | Catalysis | Enantiomers | Organosulfur compounds | Sulfoxides | Substrates | Methionine | Reductase
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10. Full Text Enantioseparation of novel chiral sulfoxides on chlorinated polysaccharide stationary phases in supercritical fluid chromatography
by West, Caroline and Konjaria, Mari-Luiza and Shashviashvili, Natia and Lemasson, Elise and Bonnet, Pascal and Kakava, Rusudan and Volonterio, Alessandro and Chankvetadze, Bezhan
Journal of Chromatography A, ISSN 0021-9673, 05/2017, Volume 1499, pp. 174 - 182
Sulfoxides | Molecular modelling | Enantiomer separation | Polysaccharide-based chiral stationary phase | Conformation | Supercritical fluid chromatography | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Chromatography, Supercritical Fluid - methods | Sulfoxides - chemistry | Carbon Dioxide - chemistry | Stereoisomerism | Chromatography, Supercritical Fluid - instrumentation | Halogenation | Polysaccharides - chemistry | Sulfoxides - isolation & purification | Methanol - chemistry | Polysaccharides | Organosulfur compounds | Chromatography | Enantiomers | Analysis
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11. Full Text Ruthenium-based chemotherapeutics: are they ready for prime time?
by Antonarakis, Emmanuel S and Emadi, Ashkan
Cancer chemotherapy and pharmacology, ISSN 0344-5704, 5/2010, Volume 66, Issue 1, pp. 1 - 9
NAMI-A | Chemotherapy | Ruthenium | Medicine & Public Health | KP1019 | ONCO4417 | Oncology | Cancer Research | Pharmacology/Toxicology | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Dimethyl Sulfoxide - therapeutic use | Drugs, Investigational - pharmacology | Indazoles - chemistry | Dimethyl Sulfoxide - chemistry | Humans | Dimethyl Sulfoxide - pharmacology | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Antineoplastic Agents - chemistry | Ruthenium Compounds - chemistry | Indazoles - pharmacology | Animals | Neoplasm Metastasis - drug therapy | Organometallic Compounds - therapeutic use | Organometallic Compounds - chemistry | Antineoplastic Agents - pharmacology | Dimethyl Sulfoxide - analogs & derivatives | Ruthenium Compounds - therapeutic use | Indazoles - therapeutic use | Organometallic Compounds - pharmacology | Drug Screening Assays, Antitumor | Ruthenium Compounds - pharmacology | Oncology, Experimental | Chemical properties | Metastasis | Research | Cancer | Index Medicus
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