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2004, 2nd ed., Advanced Texts, ISBN 1859962475, 296
Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It... 
Genetic aspects | Molecular diagnosis | Molecular aspects | Cancer | Clinical & internal medicine | Molecular Biology | General Science | Cell Biology | Cancer - Molecular diagnosis
eBook
2003, Cancer drug discovery and development., ISBN 9780896039308, x, 326
Book
2000, Current topics in microbiology and immunology, ISBN 9783540666080, Volume 249., vi, 169
Book
2011, Methods in molecular biology, ISBN 1617379786, Volume 707., xi, 282
Book
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, pp. 16538 - 16543
Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes... 
Kidneys | Cysts | Renal cell carcinoma | Alleles | Tumor suppressor genes | Kidney cells | Lesions | Genetic mutation | Tumors | Cancer | HIF | MULTIDISCIPLINARY SCIENCES | HIPPEL-LINDAU-DISEASE | kidney stem cells | CELL CARCINOMA | LESIONS | kidney cancer | INACTIVATION | Six2-Cre | EVOLUTION | GENE | TUMOR-SUPPRESSOR | VHL | MUTATIONS | EXPRESSION | BAP1 | Kidney Neoplasms - genetics | Species Specificity | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Multipotent Stem Cells - metabolism | Carcinoma, Renal Cell - genetics | Male | Kidney Failure, Chronic - pathology | Tumor Suppressor Proteins - genetics | Kidney Diseases, Cystic - genetics | Female | Precancerous Conditions - pathology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Von Hippel-Lindau Tumor Suppressor Protein - antagonists & inhibitors | Genes, Tumor Suppressor | Ubiquitin Thiolesterase - antagonists & inhibitors | Genes, Reporter | Disease Models, Animal | Genetic Predisposition to Disease | Mice, Inbred C57BL | Genes, Synthetic | Von Hippel-Lindau Tumor Suppressor Protein - physiology | Mice, Transgenic | Chromosome Mapping | Ubiquitin Thiolesterase - physiology | Ubiquitin Thiolesterase - genetics | Precancerous Conditions - genetics | Kidney Diseases, Cystic - pathology | Mice, Knockout | Kidney Failure, Chronic - genetics | Cell Lineage | Tumor Suppressor Proteins - physiology | Multipotent Stem Cells - pathology | Phenotype | Animals | Kidney Failure, Chronic - blood | Age of Onset | Mice | Models, Genetic | Mutation | Physiological aspects | Carcinoma | Kidney cancer | Rodents | Genes | Index Medicus | Biological Sciences
Journal Article
Genes and Genomics, ISSN 1976-9571, 11/2018, Volume 40, Issue 11, pp. 1225 - 1235
Hypoxia seriously affects the innate immune system of fish. However, the roles of suppressor of cytokine signaling (SOCS), pivotal anti-inflammatory genes, in... 
Takifugu fasciatus | Hypoxia | SOCS | Reoxygenation | (SOCS)-1 | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENVIRONMENT | IDENTIFICATION | GILL MORPHOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | FISH | FIBRONECTIN | TROUT ONCORHYNCHUS-MYKISS | NF-KAPPA-B | Suppressor of Cytokine Signaling 1 Protein - classification | Suppressor of Cytokine Signaling 3 Protein - chemistry | Phylogeny | RNA, Messenger - metabolism | Hypoxia - metabolism | Tissue Distribution | Fish Proteins - genetics | Suppressor of Cytokine Signaling 1 Protein - chemistry | Suppressor of Cytokine Signaling Proteins - chemistry | Suppressor of Cytokine Signaling 1 Protein - genetics | Fish Proteins - chemistry | Takifugu - metabolism | Fish Proteins - metabolism | Suppressor of Cytokine Signaling Proteins - genetics | Suppressor of Cytokine Signaling 1 Protein - metabolism | Suppressor of Cytokine Signaling 3 Protein - genetics | Fish Proteins - classification | Takifugu - genetics | Hypoxia - genetics | Animals | Suppressor of Cytokine Signaling 3 Protein - classification | Suppressor of Cytokine Signaling Proteins - classification | Suppressor of Cytokine Signaling Proteins - metabolism | Suppressor of Cytokine Signaling 3 Protein - metabolism | Hypoxia - veterinary | Genetic research | Cytokines | RNA | Analysis | Liver | Marine sciences | mRNA | Inflammation | SOCS-1 protein | Immune system | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2016, Volume 99, Issue 5, pp. 1190 - 1198
Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we... 
OCULAR MELANOMA | CELLS | COLORECTAL-CANCER | PROTEINS DLK1 | METASTASES | GENETICS & HEREDITY | RISK | EXPRESSION | RADIATION | SF3B1 | SOMATIC MUTATIONS | Melanoma - diagnosis | Exons | Humans | Middle Aged | Male | Phosphoproteins - metabolism | Case-Control Studies | RNA Splicing Factors - metabolism | DNA Copy Number Variations | Melanoma - genetics | Melanocytes - pathology | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Ubiquitin Thiolesterase - metabolism | Adult | Female | Membrane Proteins - metabolism | Eukaryotic Initiation Factor-1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Tumor Suppressor p53-Binding Protein 1 - metabolism | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Uveal Neoplasms - genetics | Genome-Wide Association Study | Tumor Suppressor Proteins - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Tumor Suppressor p53-Binding Protein 1 - genetics | Membrane Proteins - genetics | Eukaryotic Initiation Factor-1 - genetics | Ubiquitin-Protein Ligases - metabolism | GTP-Binding Protein alpha Subunits - genetics | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Ubiquitin Thiolesterase - genetics | Skin Neoplasms | Uveal Neoplasms - diagnosis | Aged | Mutation | Ubiquitin-Protein Ligases - genetics | Genetic aspects | Nucleotide sequencing | Methods | Melanoma | DNA sequencing | Metastasis | Pathogenesis | Genomics | Deoxyribonucleic acid--DNA | Index Medicus | Report
Journal Article
Journal Article
01/2011, ISBN 9781617619861
Book
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1558 - 14
The SOCS family of proteins are negative-feedback inhibitors of signalling induced by cytokines that act via the JAK/STAT pathway. SOCS proteins can act as... 
MICE LACKING SUPPRESSOR | INSULIN-RECEPTOR | STRUCTURAL BASIS | TYROSINE KINASE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CYTOKINE SIGNALING-1 | MYELOPROLIFERATIVE NEOPLASMS | ACTIVATION-LOOP | INTERFERON-ALPHA RECEPTOR | NEGATIVE REGULATOR | Phosphorylation | Humans | STAT Transcription Factors - metabolism | Suppressor of Cytokine Signaling 3 Protein - chemistry | Crystallography, X-Ray | Interferon-gamma - metabolism | Janus Kinase 1 - metabolism | Janus Kinase 2 - chemistry | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Cullin Proteins - metabolism | Protein Domains | Suppressor of Cytokine Signaling 1 Protein - chemistry | Interferon-gamma - genetics | Binding Sites | Suppressor of Cytokine Signaling 1 Protein - genetics | Signal Transduction | Janus Kinase 2 - genetics | Janus Kinase Inhibitors - chemistry | Models, Molecular | Suppressor of Cytokine Signaling 1 Protein - metabolism | Suppressor of Cytokine Signaling 3 Protein - genetics | Janus Kinase 1 - chemistry | Cullin Proteins - genetics | STAT Transcription Factors - genetics | Janus Kinase Inhibitors - metabolism | Suppressor of Cytokine Signaling 3 Protein - metabolism | Ubiquitin | Cytokines | Catalytic activity | Inflammation | Proteins | Signal transduction | Signaling | Inhibitors | γ-Interferon | Interferon | Catalysis | Inhibition | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2011, Volume 7, Issue 5, pp. 285 - 295
Journal Article
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7334, pp. 409 - 413
The mature gut renews continuously and rapidly throughout adult life, often in a damage-inflicting micro-environment. The major driving force for self-renewal... 
COLON-CANCER | INTESTINAL EPITHELIUM | TUMOR SUPPRESSION | MULTIDISCIPLINARY SCIENCES | LENTIVIRAL VECTOR | MOUSE MODEL | CELL-CYCLE ARREST | ONCOGENE-INDUCED SENESCENCE | CANCER PROGRESSION | TUMORIGENESIS | EXPRESSION | Intestinal Mucosa - metabolism | Cell Proliferation | Adenoma - genetics | Colorectal Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Casein Kinase Ialpha - genetics | Male | Loss of Heterozygosity | Wnt Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - deficiency | Tumor Suppressor Protein p53 - genetics | Adenoma - metabolism | Genes, APC | Adenoma - enzymology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cellular Senescence | Neoplasm Invasiveness - pathology | Tumor Suppressor Proteins - deficiency | Intestinal Mucosa - enzymology | Tumor Suppressor Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Fibroblasts | Female | Genes, Tumor Suppressor | Colorectal Neoplasms - metabolism | Cell Line | Colorectal Neoplasms - enzymology | Tumor Suppressor Proteins - metabolism | Signal Transduction | Casein Kinase Ialpha - deficiency | Tumor Suppressor Protein p53 - metabolism | Tumor Suppressor Protein p53 - deficiency | beta Catenin - metabolism | Disease Progression | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Cell Transformation, Neoplastic | Adenoma - pathology | Cell Line, Tumor | Mice | DNA Damage | Colorectal Neoplasms - pathology | Casein Kinase Ialpha - metabolism | Intestinal Mucosa - pathology | Index Medicus
Journal Article
1997, Frontiers in molecular biology, ISBN 0199635943, Volume 19, xix, 332