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Trends in Biochemical Sciences, ISSN 0968-0004, 06/2014, Volume 39, Issue 6, pp. 277 - 288
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 10, p. e109596
Heparanase is a beta-D-endoglucuronidase that cleaves heparan sulfate (HS), facilitating degradation of the extracellular matrix (ECM) and the release of... 
ADHESION | TOLL-LIKE RECEPTOR-4 | ROLES | CELL-MIGRATION | MULTIDISCIPLINARY SCIENCES | LIPOPOLYSACCHARIDE | MAMMALIAN HEPARANASE | LUNG INJURY | DEGRADING ENZYME | EXPRESSION | T-CELLS | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Heparitin Sulfate - pharmacology | Leukocytes, Mononuclear - secretion | Humans | Cytokines - secretion | Extracellular Space - drug effects | Glucuronidase - metabolism | Solubility | Heparitin Sulfate - metabolism | Toll-Like Receptor 4 - metabolism | Gene Expression Regulation - drug effects | Extracellular Space - metabolism | Animals | Signal Transduction - drug effects | Heparitin Sulfate - chemistry | Leukocytes, Mononuclear - cytology | Mice | Myeloid Differentiation Factor 88 - metabolism | Leukocyte migration | Leukocytes (mononuclear) | Cardiovascular disease | Arthritis | Biochemistry | Metastasis | Sulfates | Cell surface | Fragmentation | Metastases | Degradation | Interleukin 6 | Proteins | Angiogenesis | Splenocytes | Rodents | Atherosclerosis | Toll-like receptors | Peripheral blood mononuclear cells | Extracellular matrix | Biomolecules | Interleukin 8 | Immune system | Spleen | Heparan sulfate | NF-κB protein | Wound healing | Cytokines | Fragments | Inflammation | TLR4 protein | White blood cells | Tumor necrosis factor | Interleukin 10 | MyD88 protein | Sepsis | Diabetes | Sulfate | Cell migration | Chemokines | Monocyte chemoattractant protein 1 | Tumors
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 03/2019, Volume 189, Issue 3, pp. 632 - 647
Osteoarthritis (OA) is a common degenerative joint disease, characterized by cartilage loss and subchondral bone remodeling in response to abnormal mechanical... 
6-O-SULFATION | IN-VITRO | ARTICULAR-CARTILAGE | CRYSTAL-STRUCTURE | CANDIDATE GENES | GROWTH | GENE-EXPRESSION | CELL-SURFACE | PATHOLOGY | BINDING | REVEALS
Journal Article
2010, Progress in Molecular Biology and Translational Science, ISBN 9780123812827, Volume 93, Issue C, 34
Book Chapter
Journal of Biological Chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 15, pp. 12217 - 12229
Cell surface heparan sulfate (HS) is an essential regulator of cell signaling and development. HS traps signaling molecules, like Wnt in the glycosaminoglycan... 
PROTEOGLYCANS | 6-O-ENDOSULFATASES SULF1 | TOOTH DEVELOPMENT | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY |