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ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 03/2019, Volume 17, Issue 10, pp. 2770 - 2775
Total synthesis of levetiracetam, an active ingredient of epilepsy treatment medications, is reported. The reported method is based on a one-pot... 
CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | ALLYLIC ALCOHOLS | SV2A | DISCOVERY
Journal Article
Epilepsy Research, ISSN 0920-1211, 01/2019, Volume 149, pp. 88 - 91
Brivaracetam is available in intravenous formulation, and its favourable pharmacokinetic profile makes it a promising agent in the treatment of status... 
Therapeutic drug monitoring | Critical care | Outcome | Retrospective | SV2A LIGAND | REFRACTORY STATUS EPILEPTICUS | PROGNOSIS | CLINICAL NEUROLOGY | LACOSAMIDE
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 11/2018, Volume 38, Issue 11, pp. 2041 - 2052
Synaptic vesicle glycoprotein 2A (SV2A) is ubiquitously present in presynaptic terminals. Here we report kinetic modeling and test–retest reproducibility... 
neurodegeneration | Brain imaging | positron emission tomography | synapses/dendrites | kinetic modeling | PROTEIN 2A | HUMAN BRAIN | PET TRACER | RADIOTRACER | NEUROSCIENCES | SV2A | ENDOCRINOLOGY & METABOLISM | BINDING-SITE | LIGAND | HEMATOLOGY | EXPRESSION | LEVETIRACETAM
Journal Article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 09/2019, Volume 58, Issue 37, pp. 13149 - 13154
Despite a growing interest in CHF2 in medicinal chemistry, there is a lack of efficient methods for the insertion of (CHFF)-F-18 into druglike compounds.... 
REAGENT | SV2A LIGAND | ARENES | MOUSE | CHEMISTRY, MULTIDISCIPLINARY | C-H DIFLUOROMETHYLATION | IODIDES | HETEROARENES | C-H activation | TRACER | photochemistry | ARYL | radiochemistry | flow chemistry | fluorine | TRIFLUOROMETHYLATION
Journal Article
Therapeutic Advances in Neurological Disorders, ISSN 1756-2856, 2008, Volume 1, Issue 1, pp. 13 - 24
Levetiracetam (LEV) is a new antiepileptic drug that is clinically effective in generalized and partial epilepsy syndromes as sole or add-on medication.... 
Ion channels | SV2A | Synaptic transmission | Antiepileptic drugs | Epilepsy | Levetiracetam | epilepsy | antiepileptic drugs | synaptic transmission | Review | ion channels | levetiracetam
Journal Article
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2017, Volume 10, Issue 2, pp. 1998 - 2004
Breast Cancer (BCa) is a global public health problem in that is one of the main causes of deaths due to cancer in women. Synaptic Vesicle Protein (SV2) is a... 
SV2C | SV2B | SV2A | Patients with breast cancer | TOXIN TYPE-A | PATHOLOGY | CELL-LINES | TUMORS | 2A SV2A | IN-VITRO | patients with breast cancer | EXTRACELLULAR VESICLES | ONCOLOGY | BINDING-SITE | DIFFERENTIATION | BRAIN | LEVETIRACETAM
Journal Article
Brain Research, ISSN 0006-8993, 07/2019, Volume 1715, pp. 73 - 83
The function of synaptic vesicle protein 2A (SV2A) has not been clearly identified, although it has an essential role in normal neurotransmission. Changes in... 
Development | Glutamatergic terminal | SV2A | GABAergic terminal | Hippocampus | LOCALIZATION | VESICULAR GABA TRANSPORTER | PATTERNS | SYNAPTIC VESICLE PROTEIN | VGAT | NEUROSCIENCES | INHIBITORY SYNAPTOGENESIS | SYNAPSES | ASYMMETRIC ACCUMULATION | INTERNEURONS
Journal Article