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Nature communications, ISSN 2041-1723, 07/2018, Volume 9, Issue 1, pp. 2723 - 10
Regulating immunity is a leading target for cancer therapy. Here, we show that the anti-tumor immune response can be modulated by the brain's reward system, a... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Ventral Tegmental Area - immunology | Dopaminergic Neurons - pathology | Sympathetic Nervous System - drug effects | Melanoma, Experimental - drug therapy | Carcinoma, Lewis Lung - immunology | Injections, Intraventricular | Male | Myeloid-Derived Suppressor Cells - drug effects | Sympathetic Nervous System - immunology | Clozapine - pharmacology | Melanoma, Experimental - immunology | Adrenergic Neurons - pathology | Adrenergic Neurons - immunology | Bone Marrow Cells - immunology | Dopaminergic Neurons - drug effects | Bone Marrow Cells - drug effects | Sympathetic Nervous System - pathology | Adrenergic Neurons - drug effects | Dopamine - metabolism | Myeloid-Derived Suppressor Cells - pathology | Myeloid-Derived Suppressor Cells - immunology | Ventral Tegmental Area - drug effects | Dopaminergic Neurons - immunology | Immunity, Innate - drug effects | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Ventral Tegmental Area - pathology | Melanoma, Experimental - pathology | Mice, Transgenic | Clozapine - analogs & derivatives | Carcinoma, Lewis Lung - drug therapy | Stereotaxic Techniques | Animals | Norepinephrine - metabolism | Tumor Burden - drug effects | Carcinoma, Lewis Lung - pathology | Mice | Reward | Immunologic Factors - pharmacology | Brain | Immune response | Circuits | Brain tumors | Melanoma | Activation | Lung carcinoma | Sympathetic nervous system | Suppressor cells | Immunity | Immunosuppression | Immunology | Weight reduction | Bone marrow | Reinforcement | Norepinephrine | Cancer | Tumors | Immune system | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 04/2011, Volume 108, Issue 19, pp. 8030 - 8035
The maintenance of energy homeostasis is essential for life, and its dysregulation leads to a variety of metabolic disorders. Under a fed condition, mammals... 
Heart rate | Receptors | Neurons | Propionates | Myocardium | Ketone bodies | Diabetes | Physiological regulation | Lipid metabolism | Fatty acids | Probiotics | FFAR3 | Microbiota | Fasting | Superior cervical ganglion | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA, Small Interfering - genetics | Signal Transduction | Sympathetic Nervous System - drug effects | Humans | Ketone Bodies - administration & dosage | Mice, Inbred C57BL | Propionates - administration & dosage | Gene Knockdown Techniques | Mice, Knockout | Fatty Acids, Volatile - administration & dosage | 3-Hydroxybutyric Acid - administration & dosage | Animals | Ketone Bodies - physiology | Receptors, G-Protein-Coupled - deficiency | Sympathetic Nervous System - physiology | Fatty Acids, Volatile - physiology | Base Sequence | HEK293 Cells | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice | Receptors, G-Protein-Coupled - genetics | Action Potentials - drug effects | Energy Metabolism - drug effects | Receptors, G-Protein-Coupled - physiology | Physiological aspects | Glucose metabolism | G proteins | Properties | Membrane proteins | Index Medicus | Energy intake | Starvation | G protein-coupled receptors | Diabetes mellitus | Liver | Propionic acid | Energy expenditure | Homeostasis | siRNA | Glucose | Sympathetic ganglia | Energy requirements | Fermentation | Fuels | Sympathetic nervous system | ketones | Energy balance | Dietary fiber | sympathetic nerves | Metabolic disorders | microbiota | superior cervical ganglion | Biological Sciences | fasting | probiotics
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 08/2010, Volume 299, Issue 2, pp. H402 - H409
Journal Article