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Nature Neuroscience, ISSN 1097-6256, 01/2011, Volume 14, Issue 1, pp. 19 - 21
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 02/2019, Volume 54, pp. 122 - 128
The postsynaptic density (PSD) is a protein-rich assembly below the postsynaptic membrane, formed of large scaffolding proteins. These proteins carry a... 
STRUCTURAL BASIS | PDZ DOMAIN | CRYSTAL-STRUCTURE | COMPLEX REVEALS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUPERTERTIARY STRUCTURE | MUTATIONS | KINASE-ASSOCIATED PROTEIN | SYNAPTIC PLASTICITY | BINDING | SH3 DOMAIN | CELL BIOLOGY | Proteins | Nervous system diseases
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 5/2012, Volume 123, Issue 5, pp. 653 - 669
α-Synuclein (α-syn) is a presynaptic protein present at most nerve terminals, but its function remains largely unknown. The familial forms of Parkinson’s... 
Pathology | α-Synuclein | Neurosciences | Dopamine | Motor behavior | Medicine & Public Health | Substantia nigra | Electron microscopy | Neurotransmission | TARGETED OVEREXPRESSION | DYNAMIC CHANGES | ELECTRON-MICROSCOPY | NEURODEGENERATION | PATHOLOGY | NEUROSCIENCES | MICE LACKING | CLINICAL NEUROLOGY | IN-VITRO | RAT SUBSTANTIA-NIGRA | CATECHOLAMINE CONCENTRATION | FAMILIAL PARKINSONS-DISEASE | alpha-Synuclein | LEWY BODIES | Enzyme-Linked Immunosorbent Assay - methods | Intermediate Filament Proteins - ultrastructure | Motor Activity - physiology | Synaptic Vesicles - metabolism | Chromatography, High Pressure Liquid - methods | Vesicular Monoamine Transport Proteins - metabolism | Humans | Motor Activity - drug effects | Green Fluorescent Proteins - genetics | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Dopaminergic Neurons - ultrastructure | Dopamine - deficiency | Exploratory Behavior - physiology | Apomorphine - pharmacology | Time Factors | Exploratory Behavior - drug effects | Intermediate Filament Proteins - genetics | Dopaminergic Neurons - drug effects | Female | Dopamine Agonists - pharmacology | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | 3,4-Dihydroxyphenylacetic Acid - metabolism | Transduction, Genetic | Dopamine Uptake Inhibitors - pharmacology | Synaptic Vesicles - ultrastructure | Gene Expression Regulation - genetics | Amphetamine - pharmacology | Genetic Vectors - metabolism | Rats | Functional Laterality | Mutation - genetics | Potassium - pharmacology | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Substantia Nigra - drug effects | Animals | Homovanillic Acid - metabolism | Analysis of Variance | Substantia Nigra - ultrastructure | Corpus Striatum - drug effects | Electrochemistry | In Vitro Techniques | Intermediate Filament Proteins - metabolism | Nerve endings | Parkinson's disease | Neurodegenerative diseases | Neurons | Motor activity | Vectors | Synuclein | Fibers | Axons | Vesicles | Neurodegeneration | Neostriatum | Synaptic vesicles | Degeneration | Movement disorders
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 02/2019, Volume 46, Issue 2, pp. 396 - 406
PurposeA [C-11]UCB-J blocking study was performed in healthy volunteers to validate simplified, non-invasive measures for quantifying presynaptic SV2A... 
Reference tissue | Synaptic density | Positron emission tomography | Kinetic modelling | C]UCB-J | TRACER | ALZHEIMERS-DISEASE | NOISE | EXPRESSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | [C-11]UCB-J | Neuroimaging | Organic chemistry | Brain | Bias | Positron emission | Tomography | Digital video recorders | Pretreatment | Substantia alba | Estimates
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2018, Volume 37, Issue 11, p. n/a
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2017, Volume 142, Issue 4, pp. 500 - 503
This Editorial highlights a study by Frank and colleagues (2017) in the current issue of Journal of Neurochemistry. The authors report the genetic composition... 
Brain | Post-Synaptic Density | Synapses - genetics | Animals | Excitatory Postsynaptic Potentials | Membrane Proteins - genetics
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 04/2015, Volume 20, Issue 4, pp. 424 - 432
Journal Article