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FEBS Letters, ISSN 0014-5793, 01/2013, Volume 587, Issue 1, pp. 67 - 72
► Tryptophan pair (W89/W90) of synaptobrevin acts as a fusion clamp in chromaffin cells. ► W89AW90A mutant increases spontaneous release frequency. ► W89AW90A... 
Synaptobrevin | Amperometry | Membrane fusion | SNARE complex | Exocytosis | synaptobrevin 2 and cellubrevin knockout | dko | synaptobrevin W89AW90A mutants | synaptobrevin 2 | Syb2 WA | SNARE | Syb2 | wild-type synaptobrevin | Syb2 WT | SNAP (soluble NSF attachment protein) receptor | EVENTS | C-TERMINUS | VESICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADRENAL CHROMAFFIN CELLS | MOUSE | SNARE PROTEIN SNAP-25 | CA2+-TRIGGERED EXOCYTOSIS | RELEASE | CELL BIOLOGY | BIOPHYSICS | PORE | Chromaffin Cells - cytology | Tryptophan - chemistry | Alanine - chemistry | Vesicle-Associated Membrane Protein 2 - genetics | Tryptophan - metabolism | Embryo, Mammalian - metabolism | Vesicle-Associated Membrane Protein 2 - chemistry | Protein Stability | Vesicle-Associated Membrane Protein 3 - genetics | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Mutagenesis, Site-Directed | Membrane Fusion | Vesicle-Associated Membrane Protein 3 - metabolism | Cells, Cultured | Recombinant Proteins - chemistry | Alanine - metabolism | Mutant Proteins - metabolism | Mice, Knockout | Chromaffin Cells - metabolism | Patch-Clamp Techniques | Animals | Embryo, Mammalian - cytology | Mutant Proteins - chemistry | Hydrophobic and Hydrophilic Interactions | Mice | Vesicle-Associated Membrane Protein 2 - metabolism | Amino Acid Substitution | Tryptophan | snare complex | synaptobrevin | amperometry | exocytosis | membrane fusion
Journal Article
Journal Article
by Salpietro, Vincenzo and Malintan, Nancy T and Llano-Rivas, Isabel and Spaeth, Christine G and Efthymiou, Stephanie and Striano, Pasquale and Vandrovcova, Jana and Cutrupi, Maria C and Chimenz, Roberto and David, Emanuele and Di Rosa, Gabriella and Marce-Grau, Anna and Raspall-Chaure, Miquel and Martin-Hernandez, Elena and Zara, Federico and Minetti, Carlo and Salpietro, Vincenzo and Efthymiou, Stephanie and Kriouile, Yamna and El Khorassani, Mohamed and Aguennouz, Mhammed and Karashova, Blagovesta and Avdjieva, Daniela and Kathom, Hadil and Tincheva, Radka and Van Maldergem, Lionel and Nachbauer, Wolfgang and Boesch, Sylvia and Arning, Larissa and Timmann, Dagmar and Cormand, Bru and Pérez-Dueñas, Belen and Di Rosa, Gabriella and Pironti, Erica and Goraya, Jatinder S and Sultan, Tipu and Kirmani, Salman and Ibrahim, Shahnaz and Jan, Farida and Mine, Jun and Banu, Selina and Veggiotti, Pierangelo and Ferrari, Michel D and Verrotti, Alberto and Marseglia, Gian Luigi and Savasta, Salvatore and Garavaglia, Barbara and Scuderi, Carmela and Borgione, Eugenia and Dipasquale, Valeria and Cutrupi, Maria Concetta and Portaro, Simona and Sanchez, Benigno Monteagudo and Pineda-Marfa’, Mercedes and Munell, Francina and Macaya, Alfons and Boles, Richard and Heimer, Gali and Papacostas, Savvas and Manole, Andreea and Malintan, Nancy and Zanetti, Maria Natalia and Hanna, Michael G and Rothman, James E and Kullmann, Dimitri M and Houlden, Henry and Bello, Oscar D and De Zorzi, Rita and Fortuna, Sara and Dauber, Andrew and Alkhawaja, Mariam and Sultan, Tipu and Mankad, Kshitij and Vitobello, Antonio and Thomas, Quentin and Mau-Them, Frederic Tran and Faivre, Laurence and Martinez-Azorin, Francisco and Prada, Carlos E and Macaya, Alfons and Kullmann, Dimitri M and Rothman, James E and Krishnakumar, Shyam S and Houlden, Henry and Deciphering Developmental Disorders Study and SYNAPS Study Group and SYNAPS Study Grp and Deciphering Dev Disorders Study
The American Journal of Human Genetics, ISSN 0002-9297, 04/2019, Volume 104, Issue 4, pp. 721 - 730
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2011, Volume 117, Issue 4, pp. 757 - 764
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 1705
Formation of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex provides mechanical thrust for membrane fusion, but its... 
MEMBRANE-FUSION | MICROMANIPULATION | PROTEIN MOLECULE | MAGNETIC TWEEZERS | DNA | MULTIDISCIPLINARY SCIENCES | SYNAPTOTAGMIN-1 | MICROSCOPY | SYNAPTIC VESICLE FUSION | OPTICAL TWEEZERS | SYNAPTOBREVIN | Membrane Fusion | Magnetics | SNARE Proteins - metabolism
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2012, Volume 337, Issue 6100, pp. 1340 - 1343
Journal Article
Molecular and Cellular Neuroscience, ISSN 1044-7431, 2012, Volume 49, Issue 1, pp. 1 - 8
Although synaptotagmin I, which is a calcium (Ca 2+)-binding synaptic vesicle protein, may trigger soluble N-ethylmaleimide-sensitive factor attachment protein... 
Synaptobrevin | Synaptic vesicle | Neurotransmitter release | Exocytosis | SNAP-25
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 12/2017, Volume 108, pp. 298 - 306
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 9/2003, Volume 162, Issue 7, pp. 1293 - 1303
Journal Article