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American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 06/2017, Volume 312, Issue 6, pp. F1184 - F1199
Altered expression of nephrin underlies the pathophysiology of proteinuria in both congenital and acquired nephrotic syndrome. However, the epigenetic... 
Podocyte | Epigenetics | Nephrin | Gene regulation: development | METHYLATION | DOMAIN | PHYSIOLOGY | PROTEIN | TRANSCRIPTION | POTENTIAL MECHANISM | CANCER | PODOCYTES | epigenetics | gene regulation: development | NSD FAMILY | podocyte | UROLOGY & NEPHROLOGY | NEPHROTIC SYNDROME | HISTONE LYSINE METHYLTRANSFERASES | Cytoskeletal Proteins - genetics | Epigenesis, Genetic | Humans | Podocytes - enzymology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Nephrotic Syndrome - genetics | Doxorubicin | Transfection | RNA Interference | HEK293 Cells | Cytoskeletal Proteins - metabolism | Membrane Proteins - metabolism | Nephrotic Syndrome - chemically induced | Nuclear Proteins - genetics | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Disease Models, Animal | Promoter Regions, Genetic | Histone-Lysine N-Methyltransferase - genetics | Membrane Proteins - genetics | Zebrafish Proteins - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Nephrotic Syndrome - pathology | Nuclear Proteins - metabolism | Nephrotic Syndrome - enzymology | Podocytes - pathology | Zebrafish - genetics | Gene Expression Regulation, Enzymologic | Animals | Histone-Lysine N-Methyltransferase - metabolism | Adaptor Proteins, Signal Transducing - genetics | Mice, Inbred BALB C | Histones - metabolism | Zebrafish Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Methylation | Epigenetic inheritance | RNA | Genes | Genetic research | Histones | Kidney diseases | Gene expression
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2011, Volume 108, Issue 32, pp. 13130 - 13134
Journal Article
CARCINOGENESIS, ISSN 0143-3334, 11/2013, Volume 34, Issue 11, pp. 2600 - 2609
The interaction between tumors and their microenvironments leads to a vicious cycle, which strengthens both immune suppression and cancer progression. The... 
SURVIVAL | IMMUNITY | COMPLEX | METASTASIS | MICROENVIRONMENT | ONCOLOGY | ADIPONECTIN | INFLAMMATION | PROLIFERATION | WOLF-HIRSCHHORN-SYNDROME | EXPRESSION
Journal Article
Genes, Chromosomes and Cancer, ISSN 1045-2257, 02/2013, Volume 52, Issue 2, pp. 126 - 139
Histone lysine methylation plays a fundamental role in chromatin organization. Although a set of histone methyltransferases have been identified and... 
CANCER-CELLS | SET DOMAIN | OVERGROWTH PHENOTYPES | NEK7 KINASE | SOTOS-SYNDROME | ONCOLOGY | THERAPEUTIC TARGET | GENETICS & HEREDITY | GENE-EXPRESSION PROFILES | CYCLIN G1 CONSTRUCT | PROGNOSTIC MARKER | MYELOID-LEUKEMIA | Immunohistochemistry | Neoplasms - metabolism | Cell Cycle - genetics | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | Gene Expression Profiling | Flow Cytometry | Urinary Bladder Neoplasms - genetics | Neoplasms - genetics | RNA Interference | HEK293 Cells | Urinary Bladder Neoplasms - pathology | Female | Liver Neoplasms - pathology | Nuclear Proteins - genetics | Urinary Bladder Neoplasms - metabolism | Protein-Serine-Threonine Kinases - metabolism | Lung Neoplasms - genetics | Histone-Lysine N-Methyltransferase - genetics | Liver Neoplasms - genetics | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Hep G2 Cells | Cyclin G1 - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Liver Neoplasms - metabolism | Cell Line, Tumor | HeLa Cells | Neoplasms - pathology | Cyclin G1 - genetics | NIMA-Related Kinases | Chromatin | Lung cancer | Oncology, Experimental | Genes | Research | Carcinogenesis | Liver cancer | Methyltransferases | Lysine | Analysis | Histones | Universities and colleges | Methylation | Medical informatics | Cancer | Index Medicus
Journal Article
Journal Article
The Lancet, ISSN 0140-6736, 02/2018, Volume 391, Issue 10120, pp. 563 - 571
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 12/2006, Volume 194, Issue 12, pp. 1650 - 1660
Background. Gene-based vaccine delivery is an important strategy in the development of a preventive vaccine for acquired immunodeficiency syndrome (AIDS).... 
T lymphocytes | HIV/AIDS | Antigens | Cytokines | HIV | Plasmids | Vaccination | DNA | Antibodies | Placebos | HIV 1 | GENETIC IMMUNIZATION | ACUTE-RESPIRATORY-SYNDROME | CELLS | INFECTIOUS DISEASES | VIREMIA | DIFFERING PLASMID BACKBONES | RHESUS-MONKEYS | IMMUNE-RESPONSES | WEST-NILE-VIRUS | VIRUS TYPE-1 INFECTION | CYTOTOXIC T-LYMPHOCYTES | Antibody Specificity | Cytokines - analysis | Humans | AIDS Vaccines - immunology | Vaccines, DNA - immunology | Fusion Proteins, gag-pol - immunology | Male | Neutralization Tests | Gene Products, nef - genetics | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | AIDS Vaccines - adverse effects | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Fusion Proteins, gag-pol - genetics | Adult | Female | Immunization Schedule | HIV Infections - blood | Viral Envelope Proteins - genetics | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Injections, Intramuscular | Blotting, Western | HIV-1 - immunology | Vaccines, DNA - adverse effects | Adolescent | Viral Envelope Proteins - immunology | AIDS Vaccines - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | Cytokines - biosynthesis | Gene Products, nef - immunology | nef Gene Products, Human Immunodeficiency Virus | AIDS vaccines | Immunogenetics | Research
Journal Article
Journal Article
Microvascular Research, ISSN 0026-2862, 05/2020, Volume 129, p. 103955
Angiogenesis is a hallmark of many diseases. Previously, we found that Down Syndrome Candidate Region 1 Isoform 1L (DSCR1-1L) was expressed in human tumor... 
YAP1 | Histamine | Angiogenesis | TEF3 | Down Syndrome Candidate Region 1 isoform 1L
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 11/2006, Volume 4, Issue 11, pp. 811 - 820
Down syndrome candidate region 1 ( DSCR1 ) is one of more than 50 genes located in a region of chromosome 21 that has been implicated in Down syndrome. DSCR1... 
Angiogenesis | proliferation | Signaling pathway | Vascular endothelial growth factor (VEGF) | Down syndrome candidate region 1 (DSCR1) | KDR | NFATc1 | calcineurin | Flt-1 | OXIDATIVE STRESS | PROTEIN | MESSENGER-RNA | ONCOLOGY | INHIBITS CALCINEURIN | VEGF | GENE-EXPRESSION | DSCR1 ADAPT78 | CELL PROLIFERATION | VASCULAR-PERMEABILITY FACTOR | ENDOTHELIAL GROWTH-FACTOR | CELL BIOLOGY | RNA, Small Interfering - genetics | Up-Regulation | Pregnancy Proteins - antagonists & inhibitors | Humans | Pregnancy Proteins - genetics | NFATC Transcription Factors - agonists | Promoter Regions, Genetic - drug effects | RNA Interference | Membrane Proteins - physiology | Pregnancy Proteins - physiology | Muscle Proteins - antagonists & inhibitors | Intracellular Signaling Peptides and Proteins - genetics | Muscle Proteins - physiology | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - metabolism | Membrane Proteins - genetics | Proteoglycans - metabolism | Muscle Proteins - genetics | Membrane Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Neovascularization, Pathologic - metabolism | Intracellular Signaling Peptides and Proteins - physiology | Proteins - antagonists & inhibitors | Neovascularization, Physiologic - drug effects | Peptide Fragments - pharmacology | Calcineurin Inhibitors | Transfection | Active Transport, Cell Nucleus | Proteins - physiology | Molecular Chaperones | Neovascularization, Physiologic - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | NFATC Transcription Factors - metabolism | RNA, Small Interfering - pharmacology | Cells, Cultured | Protein Isoforms - physiology | Proteins - genetics | Collagen - metabolism | Animals |