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Journal Article
Journal Article
Movement Disorders, ISSN 0885-3185, 03/2008, Volume 23, Issue 4, pp. 474 - 483
Dopaminergic neurons of the substantia nigra are particularly vulnerable to oxidative and inflammatory attack. Such processes may play a crucial role in the... 
inflammation | astrocytes | MPTP | α‐synuclein | microglia | oxidative stress | oligodendroglia | Oxidative stress | Astrocytes | Oligodendroglia | Inflammation | α-synuclein | Microglia | ACTIVATED PROTEIN-KINASE | MICROGLIAL ACTIVATION | NITRIC-OXIDE SYNTHASE | alpha-synuclein | SYNERGISTIC DOPAMINERGIC NEUROTOXICITY | RAT MESENCEPHALIC CULTURES | SUBSTANTIA-NIGRA | CLINICAL NEUROLOGY | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | IN-VIVO | ROTENONE-INDUCED DEGENERATION | Immunohistochemistry | Inflammation - chemically induced | Inflammation - pathology | Microglia - metabolism | Neurons - pathology | Substantia Nigra - pathology | Humans | Oxidative Stress - physiology | Astrocytes - pathology | Substantia Nigra - immunology | Male | Substantia Nigra - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Microglia - immunology | Astrocytes - immunology | Microglia - pathology | Female | Neurons - metabolism | Parkinson Disease - metabolism | Dopamine - metabolism | Parkinson Disease - pathology | Intercellular Adhesion Molecule-1 - immunology | Parkinson Disease - immunology | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - adverse effects | Neurotoxins - adverse effects | Neurons - immunology | Haplorhini | Brain - drug effects | Animals | HLA-DR Antigens - immunology | alpha-Synuclein - metabolism | Astrocytes - metabolism
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2008, Volume 28, Issue 43, pp. 10825 - 10834
The loss of nigral dopaminergic (DA) neurons in idiopathic Parkinson's disease (PD) is believed to result from interactions between genetic susceptibility and... 
Neuroinflammation | Parkinson's disease | Tumor necrosis factor | Nigrostriatal degeneration | Dopaminergic | Parkin | MICROGLIAL ACTIVATION | INFLAMMOGEN LIPOPOLYSACCHARIDE | ALZHEIMERS-DISEASE | NECROSIS-FACTOR-ALPHA | FACTOR-KAPPA-B | REACTIVE MICROGLIA | SYNERGISTIC DOPAMINERGIC NEUROTOXICITY | SUBSTANTIA-NIGRA | NEUROSCIENCES | tumor necrosis factor | neuroinflammation | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NITRIC-OXIDE | dopaminergic | nigrostriatal degeneration | Inflammation - chemically induced | Multivariate Analysis | Heme Oxygenase-1 - metabolism | Superoxide Dismutase - genetics | Substantia Nigra - pathology | Motor Activity - drug effects | Gait Disorders, Neurologic - genetics | Substantia Nigra - metabolism | Psychomotor Performance - physiology | Tyrosine 3-Monooxygenase | Nerve Degeneration - metabolism | Exploratory Behavior - physiology | Heme Oxygenase-1 - genetics | Inflammation - complications | Polysaccharides | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | NF-E2-Related Factor 2 - genetics | Dopamine - metabolism | Superoxide Dismutase - metabolism | Cell Survival - drug effects | Cytokines - metabolism | Psychomotor Performance - drug effects | Mice, Knockout | Motor Activity - genetics | Rotarod Performance Test | Animals | Nitric Oxide Synthase Type II - genetics | NF-E2-Related Factor 2 - metabolism | Ubiquitin-Protein Ligases - deficiency | Mice | Nerve Degeneration - etiology | Gait Disorders, Neurologic - etiology | Nitric Oxide Synthase Type II - metabolism
Journal Article
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