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Nature nanotechnology, ISSN 1748-3387, 2007, Volume 2, Issue 5, pp. 275 - 284
We are learning to build synthetic molecular machinery from DNA. This research is inspired by biological systems in which individual molecules act, singly and in concert, as specialized machines... 
DESIGN | PROTEIN | MOLECULE | AUTONOMOUS DNA | MATERIALS SCIENCE, MULTIDISCIPLINARY | IN-VITRO SELECTION | NANOSCIENCE & NANOTECHNOLOGY | ENERGY-TRANSFER | SINGLE-STRANDED-DNA | B-DNA | SYNTHETIC DNA | DRIVEN DNA | Motion | Nanostructures - ultrastructure | DNA - chemistry | Nanostructures - chemistry | Nanotechnology - instrumentation | DNA - ultrastructure | Energy Transfer | Molecular Motor Proteins - chemistry | Equipment Design
Journal Article
CURRENT MEDICINAL CHEMISTRY, ISSN 0929-8673, 2017, Volume 24, Issue 15, pp. 1488 - 1503
DNA-damaging drugs in cancer present two main problems: therapeutic resistance and side effects and both can associate with DNA repair, which can be targeted in cancer therapy. Bleomycin (BLM... 
bleomycin | mitomycin C | CHEMISTRY, MEDICINAL | TOPOISOMERASE-II | DNA quadruplex | SMALL-MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | synthetic lethality | DEPENDENT PROTEIN-KINASE | DOUBLE-STRAND BREAKS | DNA repair | FANCONI-ANEMIA | TUMOR-INITIATING CELLS | CANCER STEM-CELLS | DNA-damaging drugs | PHARMACOLOGY & PHARMACY | DNA topoisomerase 1 and 2 inhibitors | HUMAN RECQ HELICASES | HIGH-RISK NEUROBLASTOMA | RNA G-QUADRUPLEX | DNA Damage - drug effects | Antibiotics, Antineoplastic - toxicity | G-Quadruplexes - drug effects | Phosphoric Diester Hydrolases - metabolism | Topoisomerase Inhibitors - toxicity | Humans | DNA Topoisomerases - metabolism | DNA Topoisomerases - chemistry | Neoplasms - drug therapy | Phosphoric Diester Hydrolases - chemistry | Topoisomerase Inhibitors - therapeutic use | Antibiotics, Antineoplastic - therapeutic use | Bleomycin - therapeutic use | DNA Repair | Topoisomerase Inhibitors - chemistry | Neoplasms - pathology | Bleomycin - toxicity | Cell proliferation | Drugs | Therapy | Protein kinase C | Toxicity | Stabilization | DNA damage | Poly(ADP-ribose) | Xeroderma pigmentosum | Lethality | Kinases | Guanine | Proteins | Antitumor agents | Bleomycin | Pathways | Ribose | Mitomycin C | Catalysis | Repair | Telomerase | Deoxyribonucleic acid--DNA | Adducts | Phosphodiesterase | Mitomycin | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Nucleotide excision repair | Crosslinking | Substrates | Telomeres | Poly(ADP-ribose) Polymerase 1 | Side effects | DNA-dependent protein kinase | DNA adducts | Cancer
Journal Article
Chemistry : a European journal, ISSN 0947-6539, 2017, Volume 23, Issue 33, pp. 7953 - 7968
Journal Article
Journal Article