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Cell, ISSN 0092-8674, 03/2019, Volume 177, Issue 1, pp. 85 - 100
Genetic interactions identify combinations of genetic variants that impinge on phenotype. With whole-genome sequence information available for thousands of... 
YEAST | PATHWAYS | FITNESS | DISSECTION | SYNTHETIC LETHAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MISSING HERITABILITY | FUNCTIONAL ANNOTATION | EPISTASIS | GENOME | REVEALS | CELL BIOLOGY | Genetic research | Genetic aspects | Analysis | Genomics
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 07/2012, Volume 6, Issue 7, p. e1724
Background: Aedes albopictus, the Asian tiger mosquito, is a vector of several arboviruses including dengue and chikungunya, and is also a significant nuisance... 
MOSQUITO-BORNE DISEASES | GENE | SYSTEMS | DOMINANT | EXPRESSION | GENOME | PARASITOLOGY | TROPICAL MEDICINE | Aedes - physiology | Mosquito Control - methods | Phenotype | Animals | Female | Male | Flight, Animal | Disease Vectors | Aedes - genetics | Actins - genetics | Aedes albopictus | Insects | Growth | Flight | Genetic aspects | Nucleotide sequencing | Identification and classification | Methods | DNA sequencing
Journal Article
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 05/2018, Volume 77, Issue 5, pp. 678 - 683
ObjectiveImplementing treat-to-target (TTT) strategies requires that patients with rheumatoid arthritis (RA) and their rheumatologists decide on how best to... 
dmards (biologic) | dmards (synthetic) | patient perspective | rheumatoid arthritis | CHOICE | RHEUMATOLOGY | Side effects | Decision making | Rheumatoid arthritis | Janus kinase | Software | Stratigraphy | Clinical medicine | Conjoint analysis | Methotrexate | Preferences | Patients | Bayesian analysis
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0172227
Tmem88a is a transmembrane protein that is thought to be a negative regulator of the Wnt signalling pathway. Several groups have used antisense morpholino... 
ACTIVATION | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | REPOPULATION | HEMATOPOIETIC STEM-CELL | CANONICAL WNT PATHWAY | SELF-RENEWAL | DIFFERENTIATION | SPECIFICATION | IDENTIFICATION | Zebrafish Proteins - classification | Embryo, Nonmammalian - metabolism | Embryo, Nonmammalian - embryology | Phylogeny | Zebrafish - embryology | Gene Knockdown Techniques - methods | In Situ Hybridization | Gene Expression Regulation, Developmental | Base Sequence | Membrane Proteins - classification | Hematopoietic System - embryology | Amino Acid Sequence | Morpholinos - genetics | Animals, Genetically Modified | Embryo, Nonmammalian - blood supply | Membrane Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Zebrafish - genetics | Sequence Homology, Amino Acid | Phenotype | Animals | Hematopoietic System - metabolism | Mutation | Zebrafish Proteins - genetics | Embryonic development | Genetic aspects | Research | Gene mutations | Zebra fish | Wnt protein | Laboratories | Genes | Erythrocytes | Oligonucleotides | Gene deletion | Experiments | Blood | Proteins | Signal transduction | Red blood cells | Clonal deletion | Phylogenetics | Deletion | Zebrafish | Cardiomyocytes | Antisense oligonucleotides | Leukocytes (neutrophilic) | Injection | Gene expression | Embryos | Mutants | Studies | o-Dianisidine | Signaling
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 1 - 11
Understanding the pattern of epistasis-the non-independence of mutations-is critical for relating genotype and phenotype. However, the combinatorial complexity... 
EMPIRICAL FITNESS LANDSCAPES | EVOLVABILITY | PATHWAYS | CONTACTS | EVOLUTION | MULTIDISCIPLINARY SCIENCES | FOURIER | MUTATIONS | ALGORITHMS | SELECTION | Proteins | Learning | Phenotypes | Solution space | Computer applications | Fluorescence | Epistasis | Mutation | Combinatorial analysis | Genotypes | Mutants
Journal Article
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