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1. Full Text N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats
by Fotio, Yannick and Ciccocioppo, Roberto and Piomelli, Daniele
PSYCHOPHARMACOLOGY, ISSN 0033-3158, 10/2020, Volume 238, Issue 1, pp. 249 - 258
Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Amides - pharmacology | Ethanolamines - pharmacology | Choice Behavior - drug effects | Endocannabinoids - pharmacology | Alcohol Drinking - drug therapy | Alcohol Drinking - psychology | Enzyme Inhibitors - pharmacology | Rats | Amidohydrolases - antagonists & inhibitors | Ethers, Cyclic - pharmacology | Male | Dose-Response Relationship, Drug | Motivation - drug effects | Self Administration | Animals | Reinforcement, Psychology | Conditioning, Operant | Oleic Acids - pharmacology | Palmitic Acids - pharmacology | Carbamates - pharmacology | Enzymes | Usage | Care and treatment | Enzyme inhibitors | Alcoholism | Physiological aspects | Hydrolases | Health aspects | Cysteine | Drinking of alcoholic beverages | Neurophysiology | Ventral tegmentum | Operant conditioning | Hydrolase | Mesencephalon | Drinking behavior | Palmitoylethanolamide | Amidase | Alcohol | Nucleus accumbens | Energy balance | Drug self-administration | Saccharin | Microinjection | Motivation | Oleic acid | N-Acylethanolamine | Reinforcement | Food consumption | Index Medicus
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2. Full Text A randomized controlled trial contrasting the effects of 4 low-calorie sweeteners and sucrose on body weight in adults with overweight or obesity
by Higgins, Kelly A and Mattes, Richard D
The American journal of clinical nutrition, ISSN 0002-9165, 2019, Volume 109, Issue 5, pp. 1288 - 1301
Appetite | Energy intake | Obesity | Sweetness | Ingestive behavior | Low-calorie sweeteners | Glycemia | Overweight | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Body Mass Index | Diterpenes, Kaurane - pharmacology | Body Weight | Dietary Sucrose - pharmacology | Sweetening Agents - pharmacology | Humans | Sucrose - analogs & derivatives | Sucrose - pharmacology | Feeding Behavior | Male | Energy Intake | Non-Nutritive Sweeteners - pharmacology | Obesity - metabolism | Young Adult | Overweight - metabolism | Diet | Adult | Aspartame - pharmacology | Female | Weight Gain - drug effects | Beverages | Saccharin - pharmacology | Stevia | Intervention | Sucrose | Para-aminobenzoic acid | Anthropometry | Body weight | Glucose | Sweeteners | Aspartame | Body mass index | Sucralose | Saccharin | Sugars | Urine | Excretion | Energy expenditure | Glucose tolerance | Organic chemistry | Body mass | Animal behavior | Body size | Adults | Beverage industry | Index Medicus | Abridged Index Medicus
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3. Full Text Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice
by Muelbl, Matthew J and Nawarawong, Natalie N and Clancy, Patrick T and Nettesheim, Catherine E and Lim, Yi Wei and Olsen, Christopher M
Psychopharmacology, ISSN 0033-3158, 7/2016, Volume 233, Issue 14, pp. 2799 - 2811
Self-administration | Neurosciences | Saccharin | Biomedicine | Sucrose | Leptin | Operant sensation seeking | Opioid | Alcohol | Cocaine | Pharmacology/Toxicology | Psychiatry | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - pharmacology | Motor Activity - drug effects | Behavior, Animal - physiology | Male | Remifentanil | Feeding Behavior - drug effects | Central Nervous System Depressants - pharmacology | Cocaine - pharmacology | Ethanol - pharmacology | Animals | Taste - drug effects | Conditioning, Operant - drug effects | Piperidines - pharmacology | Exploratory Behavior - drug effects | Behavior, Animal - drug effects | Mice | Leptin - deficiency | Street Drugs - pharmacology | Disease Models, Animal | Locomotion - drug effects | Drug abuse | Reinforcement (Psychology) | Reward (Psychology) | Psychological research | Research | Health aspects | Rodents | Alcohol use | Index Medicus
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4. Full Text Glucagon‐like peptide‐1 is specifically involved in sweet taste transmission
by Takai, Shingo and Yasumatsu, Keiko and Inoue, Mayuko and Iwata, Shusuke and Yoshida, Ryusuke and Shigemura, Noriatsu and Yanagawa, Yuchio and Drucker, Daniel J and Margolskee, Robert F and Ninomiya, Yuzo
The FASEB journal, ISSN 0892-6638, 06/2015, Volume 29, Issue 6, pp. 2268 - 2280
gustation | incretin | transmitter | Transmitter | Incretin | Gustation | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Taste Buds - physiology | Sodium Chloride - pharmacology | Sucrose - pharmacology | Chorda Tympani Nerve - drug effects | Neurons - physiology | Quinine - pharmacology | Chorda Tympani Nerve - physiology | Neurons - metabolism | Receptors, Glucagon - genetics | Receptors, Glucagon - deficiency | Hydrochloric Acid - pharmacology | Enzyme-Linked Immunosorbent Assay | Glucagon-Like Peptide 1 - metabolism | Signal Transduction | Mice, Inbred C57BL | Taste Buds - cytology | Mice, Transgenic | Mice, Knockout | Peptides - pharmacology | Microscopy, Confocal | Taste Buds - metabolism | Animals | Glucagon-Like Peptide-1 Receptor | Amiloride - pharmacology | Taste | Venoms - pharmacology | Saccharin - pharmacology | Index Medicus | Research Communication
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5. Full Text Plausible Biological Interactions of Low- and Non-Calorie Sweeteners with the Intestinal Microbiota: An Update of Recent Studies
by Plaza-Diaz, Julio and Pastor-Villaescusa, Belen and Rueda-Robles, Ascension and Abadia-Molina, Francisco and Javier Ruiz-Ojeda, Francisco
Nutrients, ISSN 2072-6643, 04/2020, Volume 12, Issue 4, p. 1153
Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Diterpenes, Kaurane - pharmacology | Glucosides - pharmacology | Gastrointestinal Microbiome - drug effects | Humans | Sucrose - analogs & derivatives | Polymers - pharmacology | Sucrose - pharmacology | Thiazines - pharmacology | Aspartame - pharmacology | Saccharin - pharmacology | Non-Nutritive Sweeteners - pharmacology | Dehydrogenases | Populations | Sucrose | Polyols | Sweeteners | Hydrogenation | Alcohols | Aspartame | Sucralose | Saccharin | Microbiota | Intestine | Intestinal microflora | Feces | Digestive tract | Sugars | Food | Consumption | Urine | Carbohydrates | Digestive system | Inflammation | Metabolism | Studies | Acids | Steviol glycosides | Index Medicus | sweetening agents | gut microbiota | nonnutritive sweeteners
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6. Full Text Calcium-Stimulated Adenylyl Cyclases Are Critical Modulators of Neuronal Ethanol Sensitivity
by Maas, James W., Jr and Vogt, Sherri K and Chan, Guy C. K and Pineda, Victor V and Storm, Daniel R and Muglia, Louis J
The Journal of neuroscience, ISSN 0270-6474, 04/2005, Volume 25, Issue 16, pp. 4118 - 4126
Protein kinase A | Adenylyl cyclase | Calcium | Ethanol | Knock-out mouse | Pharmacology | cAMP | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Pentobarbital - pharmacology | Reflex - drug effects | Male | Psychomotor Performance - physiology | Behavior, Animal | Central Nervous System Depressants - pharmacology | Dose-Response Relationship, Drug | Ethanol - blood | Reaction Time - drug effects | Neurons - physiology | Quinine - pharmacology | Phosphorylation - drug effects | Neurons - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Ataxia - physiopathology | Adenylyl Cyclases - deficiency | Blotting, Western - methods | Calcium - pharmacology | Food Preferences - drug effects | Mice, Inbred C57BL | Excitatory Amino Acid Antagonists - pharmacology | Psychomotor Performance - drug effects | Sleep - genetics | Adenylyl Cyclases - metabolism | Enzyme Activation - drug effects | Sleep - drug effects | Mice, Knockout | Isoxazoles - pharmacology | Ethanol - pharmacology | Animals | Analysis of Variance | GABA Agonists - pharmacology | Mice | Central Nervous System Depressants - blood | Dizocilpine Maleate - pharmacology | Ketamine - pharmacology | Saccharin - pharmacology | Index Medicus | Behavioral | calcium | knock-out mouse | pharmacology | adenylyl cyclase | Cognitive | protein kinase A | ethanol | Systems
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7. Full Text Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle
by Manson, Martijn L and Säfholm, Jesper and Al-Ameri, Mamdoh and Bergman, Per and Orre, Ann-Charlotte and Swärd, Karl and James, Anna and Dahlén, Sven-Erik and Adner, Mikael
European journal of pharmacology, ISSN 0014-2999, 10/2014, Volume 740, Issue Jul 15, pp. 302 - 311
Human pulmonary artery | TP receptor | Vascular smooth muscle | Taste physiology | Taste-sensing type 2 receptors (TAS2Rs) | Airway smooth muscle | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Colon - physiology | Humans | Middle Aged | Colon - drug effects | Male | Trachea - drug effects | Receptors, G-Protein-Coupled - agonists | Chloroquine - pharmacology | Noscapine - pharmacology | Aorta, Thoracic - physiology | Quinine - pharmacology | Trachea - physiology | Female | Aorta, Thoracic - drug effects | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Receptors, G-Protein-Coupled - physiology | Dextromethorphan - pharmacology | Guinea Pigs | Pulmonary Artery - drug effects | Mice, Knockout | Pulmonary Artery - physiology | Animals | Aged | Mice | Taste | Muscle Relaxation - drug effects | In Vitro Techniques | Saccharin - pharmacology | Quaternary Ammonium Compounds - pharmacology | Animal experimentation | Smooth muscle | RNA | Index Medicus | Basic Medicine | Farmakologi och toxikologi | Medical and Health Sciences | Pharmacology and Toxicology | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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8. Full Text Lesion of the rostromedial tegmental nucleus increases voluntary ethanol consumption and accelerates extinction of ethanol-induced conditioned taste aversion
by Sheth, Chandni and Furlong, Teri M and Keefe, Kristen A and Taha, Sharif A
Psychopharmacology, ISSN 0033-3158, 10/2016, Volume 233, Issue 21, pp. 3737 - 3749
Neurosciences | Biomedicine | Lateral habenula (LHb) | Ethanol | Aversion | Reward | Pharmacology/Toxicology | Rostromedial tegmental nucleus (RMTg) | Psychiatry | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Conditioning, Classical - drug effects | Rats, Long-Evans | Rats | Male | Adrenergic alpha-2 Receptor Antagonists - pharmacology | Quinine | Yohimbine - pharmacology | Central Nervous System Depressants - pharmacology | Ethanol - pharmacology | Saccharin | Self Administration | Animals | Taste - drug effects | Habenula | Tegmentum Mesencephali | Conditioning, Operant | Sweetening Agents | Pharmacology, Experimental | Alcohol, Denatured | Mesencephalon | Psychopharmacology | Alcohol | Research | Drinking of alcoholic beverages | Health aspects | Neuropsychology | Animal behavior | Rodents | Index Medicus | Original Investigation
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9. Full Text Membrane-permeable tastants amplify β2-adrenergic receptor signaling and delay receptor desensitization via intracellular inhibition of GRK2’s kinase activity
by Malach, Einav and Shaul, Merav E and Peri, Irena and Huang, Liquan and Spielman, Andrew I and Seger, Rony and Naim, Michael
Biochimica et biophysica acta. General subjects, ISSN 0304-4165, 07/2015, Volume 1850, Issue 7, pp. 1375 - 1388
Signaling | Membrane-permeable | GRK2 | Desensitization | Tastants | β2AR | β 2 AR | Humans | Cell Membrane Permeability | G-Protein-Coupled Receptor Kinase 2 - genetics | G-Protein-Coupled Receptor Kinase 2 - metabolism | G-Protein-Coupled Receptor Kinase 2 - antagonists & inhibitors | Isoquinolines - pharmacology | RNA Interference | HEK293 Cells | Caffeine - pharmacology | Phosphorylation - drug effects | Cyclic AMP - metabolism | Intracellular Space - drug effects | Receptors, Adrenergic, beta-2 - genetics | Flavanones - pharmacology | HCT116 Cells | Enzyme Inhibitors - pharmacology | Adrenergic beta-Agonists - pharmacology | Signal Transduction - genetics | Sulfonamides - pharmacology | 1-Methyl-3-isobutylxanthine - pharmacology | Blotting, Western | Receptors, Adrenergic, beta-2 - metabolism | Taste - drug effects | Signal Transduction - drug effects | Intracellular Space - metabolism | Isoproterenol - pharmacology | Tryptophan - pharmacology | HeLa Cells | Saccharin - pharmacology
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