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Immunity, ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 511 - 523
Interferon-γ (IFN-γ) promotes a population of T-bet CXCR3 regulatory T (Treg) cells that limit T helper 1 (Th1) cell-mediated pathology. Our studies... 
BET | RESPONSES | TOXOPLASMA-GONDII INFECTION | DENDRITIC CELLS | IFN-GAMMA | IN-VIVO | REGULATORY T-CELLS | IL-27 | IMMUNOLOGY | EXPRESSION | VIRAL-INFECTION | Forkhead Transcription Factors - immunology | Toxoplasma - immunology | T-Lymphocytes, Regulatory - metabolism | Oligonucleotide Array Sequence Analysis | Interleukin-17 - immunology | Male | Gene Expression Profiling | T-Box Domain Proteins - immunology | Interleukin-17 - pharmacology | T-Lymphocytes, Regulatory - immunology | Salmonella Infections, Animal - immunology | STAT1 Transcription Factor - metabolism | Flow Cytometry | Toxoplasmosis, Animal - parasitology | Forkhead Transcription Factors - metabolism | Mice, Inbred CBA | Female | Interferon-gamma - genetics | Receptors, CXCR3 - metabolism | Salmonella Infections, Animal - pathology | Salmonella typhimurium - immunology | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Mice, Transgenic | Forkhead Transcription Factors - genetics | STAT1 Transcription Factor - genetics | T-Box Domain Proteins - genetics | STAT1 Transcription Factor - immunology | T-Box Domain Proteins - metabolism | Mice, Knockout | Cell Differentiation - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Cell Differentiation - drug effects | Interferon-gamma - immunology | Receptors, CXCR3 - genetics | Receptors, CXCR3 - immunology | Salmonella Infections, Animal - microbiology | Toxoplasmosis, Animal - immunology | Mice | Interferon-gamma - pharmacology | Toxoplasmosis, Animal - pathology
Journal Article
Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 744 - 755
The microbiota stimulates inflammation, but the signaling pathways and the members of the microbiota involved remain poorly understood. We found that the... 
DEXTRAN SULFATE | IMMUNE-SYSTEM | COLITIS | MACROPHAGES | MICE | INNATE LYMPHOID-CELLS | GUT MICROBIOTA | GERM-FREE | IMMUNOLOGY | PROTEUS-MIRABILIS | BOWEL-DISEASE | Receptors, CCR2 - genetics | Inflammation - pathology | Hemolysin Proteins - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Proteus Infections - genetics | Receptors, CCR2 - immunology | Hemolysin Proteins - genetics | Salmonella Infections - genetics | Antigens, Ly - genetics | Salmonella Infections - immunology | Symbiosis - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Intestines - immunology | Proteus Infections - pathology | Monocytes - pathology | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Proteus mirabilis - immunology | Monocytes - microbiology | Salmonella Infections - pathology | Inflammation - microbiology | Microbiota - immunology | Macrophages - pathology | Proteus Infections - microbiology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Intestines - injuries | Interleukin-1beta - immunology | Inflammation - immunology | Proteus Infections - immunology | Inflammasomes - genetics | Mice, Knockout | Carrier Proteins - genetics | Salmonella - immunology | Animals | Intestines - microbiology | Antigens, Ly - immunology | Inflammasomes - immunology | Inflammation - genetics | Salmonella Infections - microbiology | Mice
Journal Article
Seminars in Immunology, ISSN 1044-5323, 2014, Volume 26, Issue 6, pp. 454 - 470
Abstract Mendelian susceptibility to mycobacterial disease (MSMD) is a rare condition characterized by predisposition to clinical disease caused by weakly... 
Allergy and Immunology | IFN-γ | Tuberculosis | BCG | ISG15 | Mycobacteriosis | IL-12 | Primary immunodeficiency | CHRONIC MULTIFOCAL OSTEOMYELITIS | INHERITED INTERLEUKIN-12 DEFICIENCY | FUNCTION STAT1 MUTATIONS | RECEPTOR BETA-1 DEFICIENCY | CHRONIC GRANULOMATOUS-DISEASE | RECESSIVE IFN-GAMMA-R1 DEFICIENCY | IMMUNOLOGY | CHRONIC MUCOCUTANEOUS CANDIDIASIS | AVIUM COMPLEX INFECTION | IFN-gamma | BACILLE CALMETTE-GUERIN | STEM-CELL TRANSPLANTATION | Candidiasis - genetics | Tuberculosis, Pulmonary - microbiology | Coinfection | Metabolism, Inborn Errors - microbiology | Humans | Salmonella Infections - genetics | Immunity, Innate - genetics | Mycobacterium tuberculosis - immunology | Salmonella Infections - immunology | Candidiasis - microbiology | Tuberculosis, Pulmonary - genetics | Host-Pathogen Interactions - immunology | Interferon-gamma - genetics | Candidiasis - immunology | Candidiasis - pathology | Severity of Illness Index | Salmonella Infections - pathology | Genetic Predisposition to Disease | Genotype | Tuberculosis, Pulmonary - pathology | Metabolism, Inborn Errors - genetics | Genetic Heterogeneity | Metabolism, Inborn Errors - immunology | Phenotype | Tuberculosis, Pulmonary - immunology | Host-Pathogen Interactions - genetics | Interferon-gamma - immunology | Salmonella Infections - microbiology | Metabolism, Inborn Errors - pathology | tuberculosis | primary immunodeficiency | mycobacteriosis
Journal Article