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Hypertension Research, ISSN 0916-9636, 2019, Volume 42, Issue 8, pp. 1114 - 1124
Loss of salt-inducible kinase 1 (SIK1) triggers an increase in blood pressure (BP) upon a chronic high-salt intake in mice. Here, we further addressed the... 
Hypertension | SIK1 | Sympathetic nervous system | High-salt intake | Dopamine β-hydroxylase | NETWORK | PHYSIOLOGY | BLOOD-PRESSURE | CENTRAL SODIUM | ETAMICASTAT | Dopamine beta-hydroxylase | TRANSPORT | PERIPHERAL VASCULAR DISEASE | DOPAMINE-RECEPTORS | KIDNEY | EXPRESSION | Salt | Nervous system | Blood pressure | Dopamine | Sodium
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e112485 - e112485
Salt-inducible kinase 1 (SIK1/Snf1lk) belongs to the AMP-activated protein kinase (AMPK) family of kinases, all of which play major roles in regulating... 
C-FOS GENE | BREAST-CANCER | MOLECULAR MECHANISMS | SIGNALING PATHWAYS | EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | AGS CELLS | CLASS IIHDAC | EXPRESSION | ADRENOCORTICAL TUMOR-CELLS | Stomach Neoplasms - genetics | Hormones - pharmacology | Phosphorylation | Adenocarcinoma - pathology | Humans | Protein-Serine-Threonine Kinases - genetics | Rats | Stomach Neoplasms - metabolism | Stomach Neoplasms - pathology | Cyclic AMP Response Element Modulator - metabolism | Cell Movement - drug effects | Adenocarcinoma - metabolism | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Adenocarcinoma - genetics | Gastrins - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Adenocarcinoma | Cholecystokinin | Stomach cancer | Phosphotransferases | Luciferase | Gastrin | Histone deacetylase | Salts | Transcription factors | Liver | Science | Metastasis | Kinases | AMP-activated protein kinase | Metastases | Proteins | LKB1 protein | Cell growth | Salt-inducible kinase | Rodents | Penicillin | c-Fos protein | Medical research | NF-κB protein | AMP | Invasiveness | Activator protein 1 | siRNA | Breast cancer | Tumor cell lines | Gene expression | Metabolism | Nuclear transport | Medicine | Signaling | Molecular modelling | Plasmids | Cell lines | Cell migration | Apoptosis | Cancer | Index Medicus
Journal Article
European Archives of Oto-Rhino-Laryngology, ISSN 0937-4477, 2/2017, Volume 274, Issue 2, pp. 757 - 763
Aim of this work was to assess the role of polymorphisms belonging to genes involved in the regulation of ionic homeostasis in Caucasian patients with Ménière... 
Ménière’s Disease | Na + -Ca ++ exchanger 1 (SLC8A1) | Medicine & Public Health | Salt inducible kinase 1 (SIK1) | Ionic transporters | Head and Neck Surgery | Genetics | Otorhinolaryngology | Neurosurgery | Ca | exchanger 1 (SLC8A1)
Journal Article
Journal of Neuroendocrinology, ISSN 0953-8194, 02/2011, Volume 23, Issue 2, pp. 136 - 142
The availability of active steroidogenic acute regulatory protein (StAR) and side‐chain cleavage cytochrome P450 (P450scc) are rate‐limiting steps for... 
steroidogenesis | ACTH | salt‐inducible kinase 1 (SIK1) | transducer of regulated CREB activity 2 (TORC2) | adrenal glands | Salt-inducible kinase 1 (SIK1) | Steroidogenesis | Adrenal glands | Transducer of regulated CREB activity 2 (TORC2) | RAT | CORTICOSTERONE RELEASE | salt-inducible kinase 1 (SIK1) | RECEPTOR ANTAGONIST ORG-34850 | TRANSCRIPTION | CREB COACTIVATOR TORC2 | TUMOR-CELLS | NEUROSCIENCES | MEDIATED GENE-EXPRESSION | STAR | SALT-INDUCIBLE KINASE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | Transcription, Genetic - drug effects | Phosphorylation | Phosphoproteins - biosynthesis | Trans-Activators | Transcriptional Activation - drug effects | Adrenal Cortex - metabolism | Cholesterol Side-Chain Cleavage Enzyme - biosynthesis | Adrenocorticotropic Hormone - pharmacology | Rats | Male | Transcription Factors - biosynthesis | Rats, Sprague-Dawley | Protein-Serine-Threonine Kinases - biosynthesis | Animals | Time Factors | Cyclic AMP Response Element-Binding Protein - metabolism | Adrenal Cortex - drug effects | Corticosterone - blood | Glucocorticoids - biosynthesis | Neurosciences | Messenger RNA | Corticosterone | Cytochrome P-450 | Physiological aspects | Blood proteins | Steroids | Index Medicus | Post-transcription | Glucocorticoids | Transcription | Cytochrome P450 | Adrenal cortex | Hormones | Steroidogenic acute regulatory protein | Cyclic AMP response element-binding protein | Adrenocorticotropic hormone | hnRNA | TORC1 protein | salt-inducible kinase | Post-translation | Original
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2013, Volume 450, Issue 2, pp. 351 - 363
ERK1/2 (extracellular-signal-regulated kinase 1/2) and their substrates RSKs (p90 ribosomal S6 kinases) phosphorylate different transcription factors,... 
Endothelin | α1-adrenergic receptor | P90 ribosomal S6 kinase (p90 RSK) | Transcriptomics | Cardiomyocyte | Mitogen-activated protein kinase (MAPK) | SNK, Student–Newman–Keuls | Lif, leukaemia inhibitory factor | Olr1, oxidized low-density lipoprotein (lectin-like) receptor 1 | Dusp, dual-specificity phosphatase | MNK, MAPK-interacting protein kinase | CREB, cAMP-response-element-binding protein | PKB, protein kinase B | ERK1 | RSK, ribosomal S6 kinase | transcriptomics | PE, phenylephrine | p90 ribosomal S6 kinase (p90 RSK) | AR, adrenergic receptor | Egr, early growth response | BH-MTC, Benjamini and Hochberg multiple testing correction | mitogen-activated protein kinase (MAPK) | ET-1, endothelin-1 | β, glycogen synthase kinase 3α | AMPKα, AMP-activated protein kinase α | Areg, amphiregulin | MKK, MAPK kinase | Rgs2, regulator of G-protein signalling 2, 24 kDa | 2, extracellular-signal-regulated kinase 1 | Atf3, activating transcription factor 3 | Klf, Krüppel-like factor | endothelin | GSK3α | Gapdh, glyceraldehyde 3-phosphate dehydrogenase | Plk2, polo-like kinase 2 | Nr4a, nuclear receptor subfamily 4, group A | Sik1, salt-inducible kinase 1 | cardiomyocyte | FDR, false discovery rate | Fosb, FBJ murine osteosarcoma viral oncogene homologue B | MSK, mitogen- and stress-activated protein kinase | IL11, interleukin 11 | NPE, nuclear protein-enriched | MAPK, mitogen-activated protein kinase | Ptgs2, prostaglandin-endoperoxide synthase 2, qPCR, quantitative PCR | Has, hyaluronan synthase
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 04/2015, Volume 96, Issue 4, pp. 682 - 690
Journal Article
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 06/2016, Volume 37, Issue 6, pp. 1601 - 1610
Journal Article
Journal Article
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2016, Volume 9, Issue 6, pp. 6076 - 6086
Background: An evolutionarily conserved gene, the Salt-inducible kinase 1 (SIK1), functions to control mammalian life span and regulates human cells... 
Salt-inducible Kinase 1 | In vivo | Hepatocellular carcinoma | Proliferation | CELLS | SUPPRESSOR | proliferation | MARKER | CATENIN | HCC | PATHOLOGY | CANCER | INDUCIBLE KINASE 1 | ONCOLOGY | GROWTH | RESISTANCE | in vivo
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 12/2018, Volume 16, Issue 6, pp. 4759 - 4764
It is well established that altered expression of microRNAs (miRs) is critical in numerous human cancer types. Nevertheless, the molecular mechanisms of many... 
MicroRNA-373 | Migration | Salt-inducible kinase 1 | Invasion | Melanoma | MEDICINE, RESEARCH & EXPERIMENTAL | salt-inducible kinase 1 | METASTASIS | melanoma | PROLIFERATION | CANCER | LINES | TO-MESENCHYMAL TRANSITION | MIR-373 | invasion | microRNA-373 | migration | SIK1 | MIRNAS | PROGRESSION
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2015, Volume 5, Issue 1, pp. 34 - 46
Abstract Objective Insulin resistance causes type 2 diabetes mellitus and hyperglycemia due to excessive hepatic glucose production and inadequate peripheral... 
Endocrinology & Metabolism | CRTC | Insulin resistance | SIK1 | Salt inducible kinase | CREB | Gluconeogenesis | HEPATIC GLUCONEOGENESIS | TORC2 | ELEMENT-BINDING PROTEIN | CREB COACTIVATOR CRTC2 | MICE LACKING | GLUCOSE-HOMEOSTASIS | METABOLISM | LIVER | ENDOCRINOLOGY & METABOLISM | EXPRESSION
Journal Article