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2003, Biostatistics, ISBN 9780824709709, Volume 11, 371
Sample size calculation plays an important role in clinical research. It is not uncommon, however, to observe discrepancies among study objectives (or... 
Clinical trials | Sampling (Statistics) | Sample Size | Statistical methods | methods | Biometry
eBook
2008, 2nd ed., Chapman & Hall/CRC biostatistics series, ISBN 1584889829, Volume 20, xiv, 465
Book
Journal of Cataract and Refractive Surgery, ISSN 0886-3350, 2015, Volume 41, Issue 12, pp. 2598 - 2604
Journal Article
Allergologia et Immunopathologia, ISSN 0301-0546, 2014, Volume 42, Issue 5, pp. 485 - 492
When designing any research project, definition is required of the sample size needed in order to carry out the study. This sample size is an estimate of the... 
ALLERGY | IMMUNOLOGY | Sample Size | Humans | Algorithms
Journal Article
Statistics in Medicine, ISSN 0277-6715, 11/2018, Volume 37, Issue 27, pp. 3904 - 3917
Grouped survival data arise often in studies where the disease status is assessed at regular visits to clinic. The time to the event of interest can only be... 
sample size calculation | proportional hazards model | grouped survival data | MEDICINE, RESEARCH & EXPERIMENTAL | TRIALS | MEDICAL INFORMATICS | VACCINE | STATISTICS & PROBABILITY | MODEL | CANCER | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | MATHEMATICAL & COMPUTATIONAL BIOLOGY | END-POINTS | COHORT | Index Medicus
Journal Article
Gastroenterology and Hepatology from Bed to Bench, ISSN 2008-2258, 2013, Volume 6, Issue 1, pp. 14 - 17
Optimum sample size is an essential component of any research. The main purpose of the sample size calculation is to determine the number of samples needed to... 
Sample size | Medical studies | Special
Journal Article
Briefings in bioinformatics, ISSN 1467-5463, 07/2018, Volume 19, Issue 4, pp. 713 - 720
Journal Article
Nephron Clinical Practice, ISSN 1660-2110, 07/2011, Volume 118, Issue 4, pp. c319 - c323
The sample size is the number of patients or other experimental units that need to be included in a study to answer the research question. Pre-study... 
Kidney Disease and Population Health | Study design | Nephrology | Sample size | Epidemiology | Statistics | Power | UROLOGY & NEPHROLOGY | Mathematical Concepts | Sample Size | Clinical Trials as Topic - methods | Research Design | Humans
Journal Article
Statistics in Medicine, ISSN 0277-6715, 2016, Volume 35, Issue 26, pp. 4718 - 4728
Journal Article
Journal of the American Statistical Association, ISSN 0162-1459, 04/2017, Volume 112, Issue 518, pp. 769 - 778
We propose a systematic method for testing and identifying a subgroup with an enhanced treatment effect. We adopts a change-plane technique to first test the... 
Subgroup analysis | Doubly robust test | Sample size calculation | Change-plane analysis | Semiparametric model | NUISANCE PARAMETER | CHANGE-POINT | MODELS | HYPOTHESIS | STATISTICS & PROBABILITY | RANDOMIZED CLINICAL-TRIALS
Journal Article
JAMA, ISSN 0098-7484, 07/2014, Volume 312, Issue 2, pp. 180 - 181
Journal Article
The AAPS Journal, ISSN 1550-7416, 3/2019, Volume 21, Issue 2, pp. 1 - 8
Reliable results of pharmacokinetic and toxicokinetic studies are vital for correct decision making during drug discovery and development. Thus, ensuring high... 
Biochemistry, general | Biotechnology | Biomedicine | Pharmacy | bioanalytical method validation | Pharmacology/Toxicology | incurred sample reanalysis (ISR) | bioanalysis | hypergeometric distribution | bridging data | IMPLEMENTATION | PHARMACOLOGY & PHARMACY | BIOEQUIVALENCE | METHODS VALIDATION | IDENTIFICATION | Information science | Analysis | Drug discovery | Index Medicus
Journal Article
BMC Medical Research Methodology, ISSN 1471-2288, 11/2018, Volume 18, Issue 1, pp. 156 - 10
BackgroundMulti-centre randomized controlled clinical trials play an important role in modern evidence-based medicine. Advantages of collecting data from more... 
Block randomisation | Linear mixed model | Random effects | CONTINUOUS OUTCOMES | HEALTH CARE SCIENCES & SERVICES | CLUSTER RANDOMIZATION | Clinical trials | Usage | Selection methods (Regression analysis) | Management | Analysis | Sample size
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 03/2016, Volume 17, Issue 1, p. 146
Background: RNA-Sequencing (RNA-seq) experiments have been popularly applied to transcriptome studies in recent years. Such experiments are still relatively... 
Power analysis | Sample size calculation | RNA-seq | Experimental design | FDR | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SEQ EXPERIMENTS | User-Computer Interface | Sample Size | Algorithms | Sequence Analysis, RNA | Transcriptome | Internet | RNA - chemistry | RNA - genetics | RNA - metabolism
Journal Article
Briefings in Bioinformatics, ISSN 1467-5463, 11/2014, Volume 16, Issue 5, pp. 813 - 819
Journal Article
Statistics in Medicine, ISSN 0277-6715, 05/2016, Volume 35, Issue 12, pp. 1944 - 1971
Journal Article
Statistics in Medicine, ISSN 0277-6715, 12/2019, Volume 38, Issue 28, pp. 5413 - 5427
Statistical inference based on correlated count measurements are frequently performed in biomedical studies. Most of existing sample size calculation methods... 
correlated count measurements | overdispersion | sample size | negative binomial distribution
Journal Article