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Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 7, pp. 3259 - 3268
Adjuvants are an essential component of modern vaccines and used for their ability to elicit immunity to coadministered Ags. Many adjuvants in clinical... 
T-CELL RESPONSES | HUMAN NEUTROPHILS | DENDRITIC CELLS | NLRP3 INFLAMMASOME | IMMUNOLOGY | THERAPEUTIC VACCINES | PARTICULATE VACCINE ADJUVANTS | NALP3 INFLAMMASOME | ANTIGEN DELIVERY | INNATE IMMUNITY | TUMOR-ANTIGEN | Interleukin-18 - immunology | Inflammasomes - metabolism | Dendritic Cells - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | Lymphocyte Activation - immunology | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Tumor Necrosis Factor-alpha - immunology | Macrophages, Peritoneal - drug effects | Cell Survival - drug effects | Antigen-Presenting Cells - metabolism | Antigen-Presenting Cells - drug effects | Phospholipids - immunology | Immunity - immunology | Macrophages, Peritoneal - immunology | Saponins - immunology | Phospholipids - pharmacology | Blotting, Western | Mice, Knockout | Microscopy, Confocal | Macrophages - metabolism | Signal Transduction - drug effects | Cholesterol - pharmacology | Killer Cells, Natural - drug effects | Mice | Killer Cells, Natural - metabolism | Macrophages, Peritoneal - metabolism | Lysosomes - immunology | Interleukin-18 - metabolism | Saponins - pharmacology | Adjuvants, Immunologic - pharmacology | Cholesterol - immunology | Tumor Necrosis Factor-alpha - deficiency | Immunity - drug effects | Signal Transduction - immunology | Lysosomes - metabolism | Inflammasomes - drug effects | Killer Cells, Natural - immunology | Dendritic Cells - drug effects | Receptors, Tumor Necrosis Factor - deficiency | Dendritic Cells - metabolism | Macrophages - immunology | Receptors, Tumor Necrosis Factor - genetics | Lysosomes - drug effects | Mice, Inbred C57BL | Interleukin-1beta - immunology | Adenosine Triphosphate - immunology | Cell Survival - immunology | Antigen-Presenting Cells - immunology | Animals | Lymphocyte Activation - drug effects | Inflammasomes - immunology | Macrophages - drug effects | Receptors, Tumor Necrosis Factor - immunology | Drug Combinations
Journal Article
Blood, ISSN 0006-4971, 03/2005, Volume 105, Issue 6, pp. 2465 - 2472
Dendritic cells (DCs) are being evaluated for cancer immunotherapy due to their unique ability to induce tumor-directed T-cell responses. Here we report that... 
MHC CLASS-I | IMMUNE-RESPONSE | PHYSIOLOGICAL STIMULI | EXOGENOUS ANTIGENS | ISCOMATRIX ADJUVANT | MELANOMA PATIENTS | NY-ESO-1 PROTEIN | HEMATOLOGY | CD8(+) T-CELL | MIGRATORY CAPACITY | CROSS-PRESENTATION | Adjuvants, Immunologic - administration & dosage | CD8-Positive T-Lymphocytes - pathology | Lymph Nodes - pathology | Saponins - administration & dosage | Cholesterol - administration & dosage | Dendritic Cells - immunology | Humans | Dendritic Cells - pathology | Cholesterol - immunology | Male | Monocytes - immunology | CD4-Positive T-Lymphocytes - pathology | Plasma Cells - pathology | Antigens, Neoplasm - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Monocytes - pathology | Female | Epitopes, T-Lymphocyte - immunology | Proteasome Endopeptidase Complex - immunology | Antigens, Neoplasm - immunology | Phospholipids - administration & dosage | Cancer Vaccines - administration & dosage | Phospholipids - immunology | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Membrane Proteins - immunology | Saponins - immunology | Lymph Nodes - immunology | Melanoma - pathology | Antigen Presentation - immunology | Membrane Proteins - administration & dosage | Cancer Vaccines - immunology | Histocompatibility Antigens Class II - immunology | Melanoma - immunology | Antigen Presentation - drug effects | Antigen-Antibody Complex - immunology | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Drug Combinations | Plasma Cells - immunology
Journal Article
Immunobiology, ISSN 0171-2985, 2014, Volume 219, Issue 7, pp. 565 - 571
Abstract Astragaloside IV is the chief ingredient of Radix Astragali, which has been used in the Traditional Chinese Medicine as a major component of many... 
Allergy and Immunology | Advanced Basic Science | Th1/Th2 | Astragaloside IV | Treg | Asthma | EOSINOPHILS | TOLERANCE | AIRWAY INFLAMMATION | IMMUNOLOGY | INTERLEUKIN-5 | IL-10 | IN-VIVO | DISEASE | MICE | EXPRESSION | Bronchial Hyperreactivity - immunology | Triterpenes - immunology | Bronchoalveolar Lavage Fluid - immunology | Drugs, Chinese Herbal - pharmacology | Th2 Cells - immunology | Interferon-gamma - metabolism | Th2 Cells - drug effects | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Forkhead Transcription Factors - metabolism | Asthma - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Anti-Asthmatic Agents - pharmacology | Th1 Cells - drug effects | Anti-Inflammatory Agents - pharmacology | Saponins - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 - immunology | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | Lung - drug effects | Inflammation - prevention & control | Mice, Inbred BALB C | Interleukin-10 - immunology | Saponins - pharmacology | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Triterpenes - pharmacology | Asthma - prevention & control | Eosinophilia - chemically induced | Anti-Inflammatory Agents - immunology | Th1 Cells - immunology | Flow Cytometry | Interleukin-10 - metabolism | Female | Lung - metabolism | Anti-Asthmatic Agents - immunology | Cytokines - immunology | Ovalbumin | Cytokines - metabolism | Interleukin-4 - metabolism | Inflammation - immunology | Bronchial Hyperreactivity - prevention & control | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | Asthma - chemically induced | Animals | Eosinophilia - immunology | Interferon-gamma - immunology | Eosinophilia - prevention & control | Lung - immunology
Journal Article
Journal Article
Vaccine, ISSN 0264-410X, 2015, Volume 33, Issue 10, pp. 1274 - 1283
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 55 - 63
Cancer vaccines aim to induce CTL responses against tumors. Challenges for vaccine design are targeting Ag to dendritic cells (DCs) in vivo, facilitating... 
MIGRATION | RESPONSES | IMMUNOTHERAPY | CONTACT HYPERSENSITIVITY | HUMANS | NEUTROPHILS | INDUCTION | NY-ESO-1 PROTEIN | LANGERHANS CELLS | TUMOR-ANTIGEN | IMMUNOLOGY | Adjuvants, Immunologic - administration & dosage | Lymph Nodes - pathology | Ovalbumin - immunology | Saponins - administration & dosage | Cholesterol - administration & dosage | Dendritic Cells - immunology | Cholesterol - immunology | Killer Cells, Natural - pathology | Melanoma, Experimental - prevention & control | Melanoma, Experimental - immunology | Natural Killer T-Cells - metabolism | Peptide Fragments - immunology | Natural Killer T-Cells - pathology | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Female | Cytotoxicity Tests, Immunologic - methods | Dendritic Cells - metabolism | Phospholipids - administration & dosage | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Phospholipids - immunology | Cells, Cultured | Melanoma, Experimental - pathology | Mice, Transgenic | Saponins - immunology | Lymph Nodes - immunology | Gene Knock-In Techniques | Quillaja - immunology | Cancer Vaccines - immunology | Animals | Ovalbumin - administration & dosage | Cross-Priming - immunology | Cell Line, Tumor | Mice | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Drug Combinations | Natural Killer T-Cells - immunology
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2004, Volume 172, Issue 5, pp. 3289 - 3296
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2009, Volume 182, Issue 3, pp. 1253 - 1259
Cancer vaccines aim to induce antitumor CTL responses, which require cross-presentation of tumor Ag to CTLs by dendritic cells (DCs). Adjuvants that facilitate... 
TPPII | IN-VIVO | PROTEASOME | DEGRADATION | ANTIBODY | GENERATION | IMMUNOLOGY | NY-ESO-1 PROTEIN | MOLECULES | EPITOPES | Endosomes - immunology | Adjuvants, Immunologic - administration & dosage | Saponins - administration & dosage | Cholesterol - administration & dosage | Cytosol - immunology | Dendritic Cells - immunology | Humans | Lysosomes - enzymology | Myeloid Progenitor Cells - enzymology | Endosomes - metabolism | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases | Antigens, Neoplasm - administration & dosage | Cytosol - enzymology | Protein Transport - immunology | Signal Transduction - immunology | Lysosomes - metabolism | Myeloid Progenitor Cells - immunology | Antigens, Neoplasm - metabolism | Membrane Proteins - metabolism | Dendritic Cells - metabolism | Endocytosis - immunology | Myeloid Progenitor Cells - metabolism | Cancer Vaccines - metabolism | Antigens, Neoplasm - immunology | Phospholipids - administration & dosage | Aminopeptidases | Cancer Vaccines - administration & dosage | Membrane Proteins - immunology | Antigen Presentation - immunology | Proteasome Endopeptidase Complex - physiology | Quillaja - immunology | Hydrolysis | Membrane Proteins - administration & dosage | Cancer Vaccines - immunology | Cell Differentiation - immunology | Cross-Priming - immunology | Dendritic Cells - enzymology | Cytosol - metabolism | Endosomes - enzymology | Serine Endopeptidases - metabolism | Lysosomes - immunology | Drug Combinations
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49780
In the last decade, the search for new vaccines against canine visceral leishmaniasis has intensified. However, the pattern related to immune protection during... 
REAL-TIME PCR | TISSUE PARASITE DENSITY | NATURALLY INFECTED-DOGS | IMMUNE-RESPONSE | NITRIC-OXIDE PRODUCTION | LONG-LASTING PROTECTION | MULTIDISCIPLINARY SCIENCES | CANINE VISCERAL LEISHMANIASIS | SAND FLY SALIVA | CLINICAL STATUS | EXCRETED-SECRETED ANTIGENS | T-Lymphocyte Subsets - immunology | Antigens, Protozoan - immunology | Leishmaniasis Vaccines - immunology | Immunoglobulin G - blood | Male | Monocytes - metabolism | Monocytes - immunology | Antigens, CD - metabolism | Antibodies, Protozoan - blood | Leishmaniasis, Visceral - veterinary | Lymphocyte Activation - immunology | Immunity, Humoral | Dog Diseases - immunology | Immunoglobulin G - immunology | Female | Histocompatibility Antigens Class II - metabolism | Leishmania infantum - genetics | B-Lymphocytes - metabolism | Dog Diseases - parasitology | Dog Diseases - prevention & control | Cytokines - immunology | Cytokines - metabolism | Adjuvants, Immunologic | Antibodies, Protozoan - immunology | Parasite Load | Immunophenotyping | Saponins - immunology | Animals | B-Lymphocytes - immunology | Histocompatibility Antigens Class II - immunology | T-Lymphocyte Subsets - metabolism | Dogs | Leishmania infantum - immunology | Antigens | Medical research | Immunoglobulin G | Vaccination | Vaccines | B cells | Leishmaniasis | Transforming growth factors | T cells | Infection | Medicine, Experimental | Health aspects | Cell proliferation | CD8 antigen | Infections | Lymphocytes T | Parasites | Proteins | Parasitic diseases | Lymphocytes | Visceral leishmaniasis | Deoxyribonucleic acid--DNA | Spleen | Vector-borne diseases | Evaluation | Immunization | Cytokines | Salivary gland | CD4 antigen | Experimental infection | Immunogenicity | Lymphocytes B | γ-Interferon | Interleukin 10 | Interferon | Saliva | Deoxyribonucleic acid | DNA
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 05/2012, Volume 90, Issue 5, pp. 540 - 552
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2002, Volume 3, Issue 1, pp. 61 - 68
Complexes of peptide and major histocompatibility complex (MHC) class 11 are expressed on the surface of antigen-presenting cells but their molecular... 
TRANSPORT | DENDRITIC CELLS | CHOLESTEROL | HLA-DR MOLECULES | SURFACE | IMMUNOLOGY | PLASMA-MEMBRANE | B-CELL LINE | T-CELLS | ANTIGEN | Antigens, CD - immunology | Humans | Molecular Sequence Data | HLA-D Antigens - immunology | Endosomes - metabolism | Membrane Proteins - analysis | CD4-Positive T-Lymphocytes - immunology | Cell Compartmentation | Membrane Microdomains - immunology | B7-2 Antigen | Lysosomes - metabolism | Antigen Presentation | Peptide Fragments - immunology | Antigens, Differentiation, B-Lymphocyte - immunology | Receptors, Antigen, T-Cell - immunology | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Membrane Glycoproteins - immunology | HLA-DP Antigens - immunology | Antibodies, Monoclonal - immunology | Amino Acid Sequence | Lymphocyte Activation | Cell Communication | Macromolecular Substances | B-Lymphocytes - drug effects | Microscopy, Confocal | B-Lymphocytes - immunology | Histocompatibility Antigens Class II - immunology | beta-Cyclodextrins | Membrane Microdomains - drug effects | Hybridomas - immunology | Lipopolysaccharides - pharmacology | Antigens - immunology | HLA-DR Antigens - immunology | Cell Line, Transformed | Cyclodextrins - pharmacology | Saponins - pharmacology | Physiological aspects | Antigen presenting cells | Lipids | Major histocompatibility complex | Research | histocompatibility antigen HLA | CD86 antigen | CD4 antigen
Journal Article