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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2017, Volume 127, Issue 6, pp. 2418 - 2432
Glucocorticoid steroids such as prednisone are prescribed for chronic muscle conditions such as Duchenne muscular dystrophy, where their use is associated with... 
TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | SKELETAL-MUSCLE | IN-VIVO | GENOME-WIDE ANALYSIS | GENE-EXPRESSION | RECEPTOR | DUCHENNE MUSCULAR-DYSTROPHY | ANNEXIN A1 | MDX MICE | MEMBRANE REPAIR | Glucocorticoids - administration & dosage | Sarcolemma - physiology | Transcriptional Activation - drug effects | Male | Receptors, Glucocorticoid - metabolism | Mice, 129 Strain | Muscular Atrophy - chemically induced | Muscle, Skeletal - drug effects | Mice, Inbred mdx | Mice, Inbred DBA | Drug Evaluation, Preclinical | Glucocorticoids - adverse effects | Gene Expression | Prednisone - administration & dosage | Prednisone - adverse effects | Drug Administration Schedule | Muscular Dystrophy, Duchenne - drug therapy | Cells, Cultured | Annexin A6 - metabolism | Regeneration | Animals | Muscle, Skeletal - physiopathology | Sarcolemma - drug effects | Protein Binding | Annexin A6 - genetics | Dosage and administration | Prednisone | Corticosteroids | Annexins | Gene expression | Steroids | Drug interactions | Muscles | Drug therapy | Observations | Atrophy, Muscular | Health aspects | Animal models | Transcription factors | Glucocorticoids | Muscle recovery | Regulatory sequences | Muscular dystrophy | Proteins | Atrophy | Histopathology | FOXO1 protein | Lasers | Rodents | Duchenne's muscular dystrophy | Forkhead protein | Children | Deoxyribonucleic acid--DNA | Chronic illnesses | Immune system | F-box protein | Musculoskeletal system | Side effects | MicroRNAs | Dystrophy | Steroid hormones
Journal Article
Neurology, ISSN 0028-3878, 06/2014, Volume 82, Issue 23, pp. 2085 - 2091
OBJECTIVE:To determine whether phosphodiesterase type 5 (PDE5) inhibition can alleviate exercise-induced skeletal muscle ischemia in boys with Duchenne... 
NNOS | SKELETAL-MUSCLE | PERINDOPRIL | SILDENAFIL | SARCOLEMMA | HUMANS | ANGIOTENSIN-II | DYSFUNCTION | EXERCISE | CLINICAL NEUROLOGY | MDX MOUSE MODEL | Piperazines - administration & dosage | Forearm - diagnostic imaging | Phosphodiesterase 5 Inhibitors - adverse effects | Sympathetic Nervous System - drug effects | Humans | Sulfones - adverse effects | Male | Purines - administration & dosage | Sympathetic Nervous System - physiopathology | Phosphodiesterase 5 Inhibitors - pharmacokinetics | Sulfones - pharmacology | Sildenafil Citrate | Vasoconstriction - physiology | Spectroscopy, Near-Infrared | Muscular Dystrophy, Duchenne - physiopathology | Muscle, Skeletal - drug effects | Forearm - blood supply | Ultrasonography | Purines - adverse effects | Piperazines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - pharmacology | Child | Carbolines - adverse effects | Muscle, Skeletal - blood supply | Muscular Dystrophy, Duchenne - drug therapy | Purines - pharmacology | Purines - pharmacokinetics | Phosphodiesterase 5 Inhibitors - administration & dosage | Sulfones - pharmacokinetics | Carbolines - administration & dosage | Muscular Dystrophy, Duchenne - complications | Piperazines - adverse effects | Piperazines - pharmacology | Vasoconstriction - drug effects | Tadalafil | Ischemia - drug therapy | Muscle, Skeletal - physiopathology | Adolescent | Exercise - physiology | Carbolines - pharmacokinetics | Carbolines - pharmacology | Ischemia - etiology | Sulfones - administration & dosage | 185
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 12/2015, Volume 156, Issue 12, pp. 4398 - 4410
Journal Article
Cardiovascular Research, ISSN 0008-6363, 2017, Volume 113, Issue 7, pp. 737 - 748
Aims The type 2 diabetic heart oxidizes more fat and less glucose, which can impair metabolic flexibility and function. Increased sarcolemmal fatty acid... 
Hypoxia | Glucose | Energy | Metabolism | Fatty acid | CARDIAC & CARDIOVASCULAR SYSTEMS | DB/DB MICE | CARDIOMYOPATHY | CARDIAC METABOLISM | MYOCARDIAL SUBSTRATE METABOLISM | INSULIN | PERFUSED HEARTS | CHAIN FATTY-ACIDS | MAGNETIC-RESONANCE | RAT-HEART | SHORT-TERM | Myocardial Reperfusion Injury - etiology | Diabetic Cardiomyopathies - metabolism | Diabetic Cardiomyopathies - drug therapy | Diabetic Cardiomyopathies - etiology | Rats, Wistar | Male | Succinimides - pharmacology | Diabetes Mellitus, Type 2 - metabolism | Diabetic Cardiomyopathies - physiopathology | Cell Hypoxia | CD36 Antigens - metabolism | Time Factors | Myocardium - metabolism | Myocardial Reperfusion Injury - drug therapy | Oleic Acids - pharmacology | Fatty Acids - metabolism | Sarcolemma - metabolism | Diabetes Mellitus, Type 2 - complications | Oxidation-Reduction | Isolated Heart Preparation | Ventricular Function, Left - drug effects | Citric Acid Cycle - drug effects | Ventricular Pressure - drug effects | Myocardial Reperfusion Injury - physiopathology | Triglycerides - metabolism | Myocardial Reperfusion Injury - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Sarcolemma - drug effects | CD36 Antigens - antagonists & inhibitors | Lipid Metabolism - drug effects | Oxidative Stress - drug effects | Energy Metabolism - drug effects | Original
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2008, Volume 105, Issue 19, pp. 7028 - 7033
We recently demonstrated early metabolic alterations in the dystrophin-deficient mdx heart that precede overt cardiomyopathy and may represent an early... 
Heart | Energy metabolism | Perfusion | Myocardium | Placebos | Cardiomyopathies | Oxides | Workloads | Transgenes | Skeletal muscle | Cardiomyopathy | Isotopes | Nitric oxide | MDX MOUSE | nitric oxide | perfusion | MOUSE HEART | MULTIDISCIPLINARY SCIENCES | CARDIAC MYOCYTES | HEART-FAILURE | SKELETAL-MUSCLE | FAILING HEART | isotopes | GLYCOPROTEIN COMPLEX | NITRIC-OXIDE | DUCHENNE MUSCULAR-DYSTROPHY | OXIDE SYNTHASE TRANSGENE | cardiomyopathy | energy metabolism | Organ Specificity - drug effects | Myocardial Contraction - drug effects | Cardiomyopathies - prevention & control | Sulfones - pharmacology | Cardiomyopathies - enzymology | Myocytes, Cardiac - enzymology | Sildenafil Citrate | Heart Rate - drug effects | Cardiomyopathies - physiopathology | Atrial Natriuretic Factor - genetics | Dystrophin - deficiency | Sarcolemma - metabolism | Atrial Natriuretic Factor - metabolism | Purines - pharmacology | Guanylate Cyclase - metabolism | Mice, Transgenic | Mitochondria - metabolism | Mitochondria - drug effects | Enzyme Activation - drug effects | Piperazines - pharmacology | Gene Expression Regulation - drug effects | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Cyclic GMP - metabolism | Signal Transduction - drug effects | Sarcolemma - drug effects | Myocytes, Cardiac - metabolism | Guanylate Cyclase - genetics | Mice | In Vitro Techniques | Care and treatment | Heart cells | Research | Properties | Cyclic guanylic acid | Prevention | Bioenergetics | Sildenafil | Heart diseases | Health aspects | Biological Sciences
Journal Article
Endocrinology, ISSN 0013-7227, 10/2013, Volume 154, Issue 10, pp. 3764 - 3775
The orexigenic and anabolic effects induced by ghrelin and the synthetic GH secretagogues (GHSs) are thought to positively contribute to therapeutic approaches... 
GHRELIN RECEPTOR LIGANDS | OLDER-ADULTS | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGICAL IN-VITRO | GH SECRETAGOGUES | VENTRICULAR MYOCYTES | VIVO EVALUATIONS | CELL-LINES | UBIQUITIN LIGASES | EXPRESSION | DES-ACYL GHRELIN | Rats, Wistar | Receptors, Ghrelin - agonists | Sarcoplasmic Reticulum - drug effects | Ghrelin - analogs & derivatives | Mitochondria, Muscle - metabolism | Cytosol - drug effects | Male | Muscle, Skeletal - metabolism | Structure-Activity Relationship | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Oligopeptides - adverse effects | Spiro Compounds - adverse effects | Piperidines - pharmacology | Pituitary Gland, Anterior - secretion | Muscle, Skeletal - drug effects | Receptors, Ghrelin - metabolism | Growth Hormone - secretion | Sarcoplasmic Reticulum - metabolism | Sarcolemma - metabolism | Appetite Stimulants - pharmacology | Cell Line | Cell Survival - drug effects | Rats | Receptors, Ghrelin - antagonists & inhibitors | Ghrelin - metabolism | Animals | Calcium Signaling - drug effects | Cell Membrane Permeability - drug effects | Piperidines - adverse effects | Sarcolemma - drug effects | Cytosol - metabolism | Pituitary Gland, Anterior - drug effects | Mitochondria, Muscle - drug effects | Oligopeptides - pharmacology | Spiro Compounds - pharmacology | Appetite Stimulants - adverse effects
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2012, Volume 448, Issue 1, pp. 43 - 53
Journal Article
Molecular Therapy, ISSN 1525-0016, 06/2017, Volume 25, Issue 6, pp. 1395 - 1407
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 2014, Volume 307, Issue 6, pp. H895 - 903
Journal Article