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American Journal of Surgical Pathology, ISSN 0147-5185, 09/2009, Volume 33, Issue 9, pp. 1401 - 1408
Gastrointestinal stromal tumors (GISTs), KIT or platelet derived growth factor receptor alpha (PDGFRA) signaling driven mesenchymal tumors of the... 
PDGFRA | Chloride channel protein | Sarcoma | DOG1 | KIT | Mutation | Gastrointestinal stromal tumor | PDGFRA MUTATIONS | GASTRIC TUMORS | SURGERY | sarcoma | MARKER | KINASE-C-THETA | MONOCLONAL-ANTIBODY | PATHOLOGY | mutation | chloride channel protein | gastrointestinal stromal tumor | TERM-FOLLOW-UP | EXPRESSION | PKC-THETA | MORPHOLOGY | Immunohistochemistry | Myenteric Plexus - pathology | Predictive Value of Tests | Anoctamin-1 | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Stomach Neoplasms - metabolism | Leiomyoma - metabolism | Myenteric Plexus - metabolism | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Esophageal Neoplasms - pathology | Leiomyoma - pathology | Chloride Channels | Gastrointestinal Stromal Tumors - diagnosis | Esophageal Neoplasms - metabolism | Mesenchymoma - diagnosis | Biomarkers, Tumor - metabolism | Membrane Proteins - metabolism | Intestinal Neoplasms - diagnosis | Colorectal Neoplasms - metabolism | Peritoneal Neoplasms - pathology | Mesenchymoma - metabolism | Diagnosis, Differential | Stomach Neoplasms - diagnosis | Intestinal Neoplasms - metabolism | Sarcoma, Synovial - metabolism | Peritoneal Neoplasms - metabolism | Gastrointestinal Stromal Tumors - metabolism | Mesenchymoma - secondary | Colorectal Neoplasms - pathology | Sarcoma, Synovial - pathology | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2018, Volume 69, Issue 4, pp. 581 - 593.e7
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 10/2018, Volume 57, Issue 10, pp. 1342 - 1357
Ewing sarcoma (EWS) is a soft tissue and bone tumor that occurs primarily in adolescents and young adults. In most cases of EWS, the chimeric transcription... 
de novo serine‐glycine biosynthesis | Ewing sarcoma | metabolism | glutamine | ROS | de novo serine-glycine biosynthesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | MULTICELLULAR TUMOR SPHEROIDS | PROLIFERATION | BREAST-CANCER | LUNG-CANCER | AMINO-ACID | ONCOLOGY | PROSTATE-CANCER | GROWTH | TRANSCRIPTIONAL TARGET | EXPRESSION | ONE-CARBON METABOLISM | Multifunctional Enzymes - genetics | Oncogene Proteins, Fusion - metabolism | Humans | Gene Expression Regulation, Neoplastic | Sarcoma, Ewing - pathology | Cell Survival - genetics | Glutamine - metabolism | Multienzyme Complexes - metabolism | Apoptosis - genetics | Serine - biosynthesis | Aminohydrolases - genetics | Multifunctional Enzymes - metabolism | Bone Neoplasms - pathology | Bone Neoplasms - metabolism | Proto-Oncogene Protein c-fli-1 - metabolism | HEK293 Cells | Minor Histocompatibility Antigens - genetics | Bone Neoplasms - genetics | Amino Acid Transport System ASC - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Sarcoma, Ewing - metabolism | Phosphoglycerate Dehydrogenase - metabolism | Proto-Oncogene Protein c-fli-1 - genetics | HCT116 Cells | RNA-Binding Protein EWS - genetics | Glycine - biosynthesis | Amino Acid Transport System ASC - metabolism | Multienzyme Complexes - genetics | RNA-Binding Protein EWS - metabolism | Phosphoglycerate Dehydrogenase - genetics | Formate-Tetrahydrofolate Ligase - metabolism | Minor Histocompatibility Antigens - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Formate-Tetrahydrofolate Ligase - genetics | Aminohydrolases - metabolism | Sarcoma, Ewing - genetics | Glucose metabolism | International trade | Enzymes | Sarcoma | Analysis | Amino acids | Carbon cycle (Biogeochemistry) | Adolescence | Reactive oxygen species | Serine | DNA damage | Biosynthesis | Bone tumors | Glycine | Ewing's sarcoma | Proteins | Transcription activation | Adolescents | Redox properties | Damage accumulation | Deoxyribonucleic acid--DNA | Cell survival | Young adults | Risk groups | Metabolism | Nutrient uptake | Gene expression | Survival | Carbon cycle | Gene silencing | Adults | Transporter | Tumors | Apoptosis | Glutamine | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 05/2010, Volume 24, Issue 9, pp. 916 - 932
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2007, Volume 28, Issue 5, pp. 823 - 837
Tandem PHD and bromodomains are often found in chromatin-associated proteins and have been shown to cooperate in gene silencing. Each domain can bind... 
PROTEINS | DNA | LOCALIZATION | RECOGNITION | RING | BIOCHEMISTRY & MOLECULAR BIOLOGY | ZINC-FINGER PROTEINS | COMPLEXES | TRANSCRIPTIONAL REPRESSION | SUMO MODIFICATION | KAP-1 COREPRESSOR | BINDING | CONTRIBUTES | CELL BIOLOGY | Chromatin - metabolism | Autoantigens - metabolism | Mi-2 Nucleosome Remodeling and Deacetylase Complex | Saccharomyces cerevisiae - genetics | Humans | Protein Methyltransferases - genetics | RING Finger Domains | Tripartite Motif-Containing Protein 28 | Autoantigens - genetics | Bone Neoplasms - pathology | Protein Methyltransferases - metabolism | Repressor Proteins - antagonists & inhibitors | Bone Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Kidney - metabolism | Transcription, Genetic | Bone Neoplasms - genetics | DNA Helicases - genetics | Osteosarcoma - metabolism | Repressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Histone Deacetylases - genetics | Small Ubiquitin-Related Modifier Proteins - metabolism | Cells, Cultured | Gene Expression Regulation | Gene Silencing | Ubiquitin-Protein Ligases - metabolism | Adenosine Triphosphatases - metabolism | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Ubiquitin-Conjugating Enzymes - genetics | DNA-Binding Proteins - genetics | DNA Helicases - metabolism | Two-Hybrid System Techniques | Ubiquitin-Conjugating Enzymes - metabolism | Adenosine Triphosphatases - genetics | Protein Processing, Post-Translational | Osteosarcoma - genetics | Lysine - chemistry | Ubiquitin-Protein Ligases - genetics | Osteosarcoma - pathology | Saccharomyces cerevisiae - growth & development | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 04/2010, Volume 464, Issue 7290, pp. 852 - 857
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 04/2017, Volume 216, Issue 4, pp. 1015 - 1034
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, pp. 22113 - 22113
Journal Article
Genes and Development, ISSN 0890-9369, 08/2018, Volume 32, Issue 15-16, pp. 1008 - 1019
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2012, Volume 181, Issue 5, pp. 1782 - 1795
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2007, Volume 12, Issue 4, pp. 342 - 354
The tumor suppressor p53 is a transcription factor that responds to cellular stresses by initiating cell cycle arrest or apoptosis. One transcriptional target... 
PROTEINS | CELLCYCLE | TRANSCRIPTIONAL ACTIVATION | CHK2 KINASE | PROTEIN | ONCOLOGY | DNA-DAMAGE RESPONSE | MDM2 | ATM | P53 PATHWAY | CELL-GROWTH | IONIZING-RADIATION | PPM1D | Protein-Serine-Threonine Kinases - deficiency | Fibroblasts - enzymology | Phosphorylation | Proto-Oncogene Proteins c-mdm2 - genetics | Humans | Phosphoprotein Phosphatases - metabolism | Ubiquitin - metabolism | Homeostasis | DNA-Binding Proteins - deficiency | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Transfection | RNA Interference | Time Factors | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Ubiquitin Thiolesterase - metabolism | Transcription, Genetic | Signal Transduction - radiation effects | Proto-Oncogene Proteins c-mdm2 - metabolism | Osteosarcoma - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Tumor Suppressor Proteins - metabolism | Osteosarcoma - enzymology | Cell Cycle Proteins - metabolism | Protein Phosphatase 2C | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Serine - metabolism | Mice, Knockout | Animals | Phosphoprotein Phosphatases - genetics | Fibroblasts - radiation effects | Cell Line, Tumor | Phosphoprotein Phosphatases - deficiency | Mice | DNA Damage | Mutation | Osteosarcoma - genetics | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Specific Peptidase 7 | RNA, Small Interfering - metabolism | Index Medicus
Journal Article