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Journal Article
Brazilian Journal of Medical and Biological Research, ISSN 0100-879X, 06/2006, Volume 39, Issue 6, pp. 801 - 807
Piplartine {5,6-dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)pyridinone} and piperine... 
Antitumor activity | Piperine | Toxicity | Piplartine | toxicity | MEDICINE, RESEARCH & EXPERIMENTAL | piplartine | piperine | PROLIFERATION | ABORESCENS | B16F-10 MELANOMA-CELLS | POTENT INHIBITOR | DIET | antitumor activity | BIOLOGY | MICE | CANCER PREVENTION | CYTOTOXIC PYRIDONE ALKALOIDS | Piperidones - toxicity | Neoplasm Transplantation | Liver - pathology | Plant Extracts - toxicity | Kidney - pathology | Alkaloids - isolation & purification | Polyunsaturated Alkamides - therapeutic use | Sarcoma 180 - pathology | Piperidones - therapeutic use | Polyunsaturated Alkamides - toxicity | Spleen - drug effects | Sarcoma 180 - drug therapy | Benzodioxoles - toxicity | Liver - drug effects | Female | Benzodioxoles - therapeutic use | Piperidines - isolation & purification | Antineoplastic Agents, Phytogenic - therapeutic use | Polyunsaturated Alkamides - isolation & purification | Spleen - pathology | Benzodioxoles - isolation & purification | Piperidones - isolation & purification | Disease Models, Animal | Piperidines - toxicity | Alkaloids - toxicity | Kidney - drug effects | Plant Extracts - isolation & purification | Piper - chemistry | Antineoplastic Agents, Phytogenic - toxicity | Animals | Piperidines - therapeutic use | Plant Roots - chemistry | Alkaloids - therapeutic use | Cell Proliferation - drug effects | Mice | Plant Extracts - therapeutic use | Antineoplastic Agents, Phytogenic - isolation & purification
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 133, Issue 2, pp. 96 - 102
Journal Article
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 11/2014, Volume 11, Issue 11, pp. 4118 - 4129
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 03/2015, Volume 229, pp. 119 - 131
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 01/2017, Volume 94, Issue Pt A, pp. 735 - 744
Pinecone polyphenols are bioactive dietary constituents that enhance health and help prevent and treat cancer through improving antioxidant and... 
Immunoregulatory activity | Antitumor activity | Pinecone polyphenols | Pinus koraiensis | Antioxidant activity | VITRO | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-CYCLE ARREST | COLON | INDUCTION | POLYSACCHARIDE INDUCES APOPTOSIS | GROWTH | CHEMISTRY, APPLIED | IMMUNOMODULATORY ACTIVITIES | EXPRESSION | CANCER CHEMOPREVENTION | EXTRACT | Neoplasm Transplantation | Superoxide Dismutase - genetics | Proto-Oncogene Proteins c-bcl-2 - immunology | Spleen - immunology | Apoptosis - drug effects | Immunologic Factors - isolation & purification | bcl-2-Associated X Protein - agonists | Polyphenols - pharmacology | Caspase 3 - immunology | Sarcoma 180 - pathology | Superoxide Dismutase - blood | Male | Spleen - drug effects | Sarcoma 180 - blood | Sarcoma 180 - drug therapy | Lymphocytes - immunology | Malondialdehyde - blood | Caspase 3 - genetics | bcl-2-Associated X Protein - genetics | Pinus - chemistry | Polyphenols - isolation & purification | Gene Expression | Administration, Oral | Antioxidants - pharmacology | Mice, Inbred Strains | Sarcoma 180 - genetics | bcl-2-Associated X Protein - immunology | Animals | Tumor Burden - drug effects | Antioxidants - isolation & purification | Cyclophosphamide - pharmacology | Lymphocytes - drug effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Immunologic Factors - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Glutathione - blood | Prevention | Proteins | Antioxidants | Polyphenols | Sarcoma | Cancer | DNA polymerases | Superoxide
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 6/2016, Volume 33, Issue 6, pp. 1472 - 1485
To develop a multi-functional theranostic nanoplatform with increased tumor retention, improving antitumor efficacy and decreased side effects of chemotherapy... 
Biochemistry, general | Biomedical Engineering | Biomedicine | Pharmacy | bioimaging | GO@Gd | Medical Law | hybrid nanosystem | Pharmacology/Toxicology | theranostic | tumor-targeting | CANCER-CELLS | GRAPHENE OXIDE | GADOPENTETATE DIMEGLUMINE | PHOTODYNAMIC THERAPY | GENE DELIVERY | DRUG-DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | FULLERENE | PHARMACOLOGY & PHARMACY | BIOMEDICAL APPLICATIONS | SURFACE-CHEMISTRY | Gadolinium - administration & dosage | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Photochemotherapy - methods | Humans | Oxides - chemistry | Sarcoma 180 - pathology | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Spectroscopy, Fourier Transform Infrared | Folic Acid - administration & dosage | Sarcoma 180 - drug therapy | Breast Neoplasms - metabolism | Drug Carriers | Dose-Response Relationship, Drug | Nanoparticles | Sarcoma 180 - metabolism | Tissue Distribution | Theranostic Nanomedicine - methods | Antibiotics, Antineoplastic - chemistry | Biological Transport | MCF-7 Cells | Time Factors | Contrast Media - administration & dosage | Sarcoma 180 - diagnostic imaging | Female | Doxorubicin - metabolism | Scattering, Radiation | Graphite - chemistry | Doxorubicin - administration & dosage | Microscopy, Electron, Transmission | Folic Acid - chemistry | Breast Neoplasms - drug therapy | Spectrophotometry, Ultraviolet | Gadolinium - chemistry | Antibiotics, Antineoplastic - administration & dosage | Xenograft Model Antitumor Assays | Magnetic Resonance Imaging | Animals | Breast Neoplasms - pathology | Lasers, Semiconductor | Photochemotherapy - instrumentation | Folic Acid - metabolism | Contrast Media - chemistry | Mice, Inbred BALB C | Drugs | Chemotherapy | Drug delivery systems | Ablation (Surgery) | Anthracyclines | Graphene | Polyethylene glycol | Polyols | Folic acid | Contrast media | Vehicles | Cancer | Nanocomposites | Cancer therapies | Index Medicus
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 11/2014, Volume 88, Issue 3, pp. 737 - 745
Cancer stem cells (CSCs), also known as tumor-initiating cells, which constitute a subpopulation of tumor cells, are key drivers of tumorigenesis and potential... 
CD133+ cells | Metformin | Cancer stem-like cells | Coencapsulation | S180 cell | Epirubicin liposomes | CD133 + cells | BREAST-CANCER | INITIATING CELLS | PROSPECTIVE IDENTIFICATION | GROWTH | PHARMACOLOGY & PHARMACY | CD133(+) cells | LEUKEMIA | Neoplasm Transplantation | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Metformin - therapeutic use | Neoplastic Stem Cells - drug effects | Glycoproteins - metabolism | Sarcoma 180 - pathology | Male | Polyethylene Glycols - chemistry | Epirubicin - administration & dosage | Drug Carriers - chemistry | Sarcoma 180 - drug therapy | Antigens, CD - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasm Recurrence, Local - pathology | Sarcoma 180 - metabolism | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Surface Properties | Drug Compounding | Neoplastic Stem Cells - pathology | Metformin - administration & dosage | Microscopy, Electron, Transmission | Neoplasm Recurrence, Local - metabolism | Neoplasm Recurrence, Local - prevention & control | Metformin - pharmacology | Mice, Inbred Strains | AC133 Antigen | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cell Line, Tumor | Epirubicin - therapeutic use | Cell Proliferation - drug effects | Liposomes | Cell Cycle - drug effects | Epirubicin - pharmacology
Journal Article