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Modern Pathology, ISSN 0893-3952, 10/2011, Volume 24, Issue 10, pp. 1313 - 1319
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0185321
Background Alveolar soft part sarcoma (ASPS) is an extremely rare metastatic soft tissue tumor with a poor prognosis for which no effective systemic therapies... 
SELECTIVE INHIBITOR | ANGIOGENESIS | TISSUE SARCOMA | MULTIDISCIPLINARY SCIENCES | MUSCULOSKELETAL ONCOLOGY GROUP | TYROSINE KINASE INHIBITOR | TIVANTINIB ARQ 197 | MET INHIBITION | TRANSCRIPTION FACTOR | CYTOTOXIC ACTIVITY | CANCER | Proto-Oncogene Proteins c-met - metabolism | Anilides - therapeutic use | Humans | Dasatinib - therapeutic use | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Sarcoma, Alveolar Soft Part - pathology | Antineoplastic Agents - therapeutic use | Sarcoma, Alveolar Soft Part - drug therapy | Xenograft Model Antitumor Assays | Animals | Sulfonamides - therapeutic use | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | src-Family Kinases - metabolism | Cell Line, Tumor | Female | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Sarcoma, Alveolar Soft Part - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Pyridines - therapeutic use | Sarcoma | Drug therapy | Research | Cell proliferation | Phosphorylation | Target recognition | Cytotoxicity | Oncology | Metastasis | Kinases | Assaying | Bone surgery | Cancer therapies | Western blotting | Metastases | Anticancer properties | Angiogenesis | Antitumor agents | Inhibition | Alveoli | Tyrosine | Medical research | Gene expression | Medicine | Studies | Experimental design | Orthopedics | Medical prognosis | Response rates | Antitumor activity | In vivo methods and tests
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 11/2009, Volume 64, Issue 6, pp. 1059 - 1069
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Current chemotherapy regimes include the topoisomerase II poison etoposide and the... 
Cytotoxicity | Topoisomerase poisons | Acridine-4-carboxamides | Rhabdomyosarcoma | Transcription inhibitors | DNA-BINDING | POTENTIAL ANTITUMOR AGENTS | METASTATIC RHABDOMYOSARCOMA | INTERGROUP-RHABDOMYOSARCOMA | PHASE-II | SOLID-TUMOR-ACTIVITY | ONCOLOGY | 120-H INFUSION | COMBINATION CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | SOFT-TISSUE SARCOMA | Nucleic Acid Synthesis Inhibitors - pharmacology | Topoisomerase Inhibitors | Humans | Rhabdomyosarcoma - metabolism | DNA-Binding Proteins - metabolism | Rhabdomyosarcoma, Embryonal - genetics | Rhabdomyosarcoma, Alveolar - metabolism | Antigens, Neoplasm - metabolism | Inhibitory Concentration 50 | Rhabdomyosarcoma - drug therapy | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Rhabdomyosarcoma, Alveolar - drug therapy | Cell Survival - drug effects | DNA Topoisomerases, Type II - metabolism | Aminoacridines - pharmacology | Phenazines - pharmacology | DNA Topoisomerases, Type I - metabolism | Rhabdomyosarcoma, Alveolar - genetics | Rhabdomyosarcoma, Embryonal - enzymology | Enzyme Inhibitors - pharmacology | Rhabdomyosarcoma, Embryonal - drug therapy | Rhabdomyosarcoma, Alveolar - enzymology | Rhabdomyosarcoma, Embryonal - metabolism | Acridines - pharmacology | Cell Line, Tumor | Chemotherapy | Sarcoma | Analysis | DNA | Genetic research | Etoposide | Universities and colleges | Public health | Cancer | Index Medicus
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 43, pp. 70832 - 70844
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 04/2015, Volume 33, Issue 4, pp. 1667 - 1674
Journal Article
Pathology Research and Practice, ISSN 0344-0338, 1986, Volume 181, Issue 3, pp. 357 - 361
A case of alveolar soft part sarcoma was studied by light and electron microscopy and by electron microscopic enzyme histochemistry of adenosine triphosphatase... 
Crystalline inclusions | Alveolar soft part sarcoma | ATPase | Nucleotidases - metabolism | 5'-Nucleotidase | Muscular Diseases - enzymology | Humans | Adenosine Triphosphatases - metabolism | Adult | Male | Sarcoma - enzymology | Cytoplasm - ultrastructure | Muscular Diseases - pathology | Sarcoma - pathology
Journal Article
Cell death & disease, ISSN 2041-4889, 10/2016, Volume 7, Issue 10, pp. e2406 - e2406
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 365, Issue 1, pp. 37 - 46
Abstract Eribulin, a novel microtubule-interfering drug, was recently shown to exhibit high antitumor activity in vivo against various pediatric cancers. Here,... 
Hematology, Oncology and Palliative Medicine | Eribulin | PLK1 | Rhabdomyosarcoma | Apoptosis | TARGET | PROTEIN | NEUROBLASTOMA-CELLS | PRECLINICAL TESTING PROGRAM | MESYLATE | ONCOLOGY | PATHWAY | IN-VIVO | RESISTANCE | ENDONUCLEASE-G | SOFT-TISSUE SARCOMA | Apoptosis - drug effects | Tubulin Modulators - pharmacology | Furans - pharmacology | Humans | Rhabdomyosarcoma - pathology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Dose-Response Relationship, Drug | Caspases - metabolism | Transfection | RNA Interference | Time Factors | Endodeoxyribonucleases - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Ketones - pharmacology | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Proto-Oncogene Proteins - antagonists & inhibitors | Pteridines - pharmacology | Cell Cycle Proteins - metabolism | Chick Embryo | Drug Synergism | Rhabdomyosarcoma - enzymology | Endodeoxyribonucleases - genetics | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Rhabdomyosarcoma - genetics | Chemotherapy | Polo | Analysis | Cancer | Nucleases | Kinases | Cell cycle | Index Medicus
Journal Article
Histopathology, ISSN 0309-0167, 04/2006, Volume 48, Issue 5, pp. 569 - 578
Journal Article
Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 48, pp. 78883 - 78895
The nuclear export protein, exportin-1 (XPO1/CRM1), is overexpressed in many cancers and correlates with poor prognosis. Selinexor, a first-in-class Selective... 
NF-κB | XPO1 | SINE | Proteasome inhibitors | Selinexor | SIGNAL | ACTIVATION | PHOSPHORYLATION | proteasome inhibitors | NECROSIS-FACTOR-ALPHA | CRM1 | CANCER | CELL BIOLOGY | NF-kappa B | selinexor | SERUM-LEVELS | PROTEINS | CORRELATE | KINASES | Osteosarcoma - drug therapy | Phosphorylation | Humans | Drug Resistance, Neoplasm | NF-KappaB Inhibitor alpha - genetics | NF-kappa B - metabolism | Bortezomib - pharmacology | Bone Neoplasms - pathology | Transcription Factor RelA - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Cell Nucleus - metabolism | Fibrosarcoma - pathology | Transfection | RNA Interference | Time Factors | Cell Nucleus - pathology | Proteolysis | Female | Bone Neoplasms - drug therapy | Cell Death - drug effects | Hydrazines - pharmacology | Bone Neoplasms - enzymology | Osteosarcoma - enzymology | Proteasome Inhibitors - pharmacology | Mice, SCID | Mice, Inbred ICR | Drug Synergism | Triazoles - pharmacology | Fibrosarcoma - genetics | Animals | Karyopherins - metabolism | NF-kappa B - genetics | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Active Transport, Cell Nucleus - drug effects | NF-KappaB Inhibitor alpha - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Cell Line, Tumor | Proteasome Endopeptidase Complex - metabolism | Cell Nucleus - drug effects | Fibrosarcoma - enzymology | Karyopherins - antagonists & inhibitors | Fibrosarcoma - drug therapy | Osteosarcoma - pathology | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article