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Journal Article
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 10/2018, Volume 57, Issue 10, pp. 1342 - 1357
Ewing sarcoma (EWS) is a soft tissue and bone tumor that occurs primarily in adolescents and young adults. In most cases of EWS, the chimeric transcription... 
de novo serine‐glycine biosynthesis | Ewing sarcoma | metabolism | glutamine | ROS | de novo serine-glycine biosynthesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | MULTICELLULAR TUMOR SPHEROIDS | PROLIFERATION | BREAST-CANCER | LUNG-CANCER | AMINO-ACID | ONCOLOGY | PROSTATE-CANCER | GROWTH | TRANSCRIPTIONAL TARGET | EXPRESSION | ONE-CARBON METABOLISM | Multifunctional Enzymes - genetics | Oncogene Proteins, Fusion - metabolism | Humans | Gene Expression Regulation, Neoplastic | Sarcoma, Ewing - pathology | Cell Survival - genetics | Glutamine - metabolism | Multienzyme Complexes - metabolism | Apoptosis - genetics | Serine - biosynthesis | Aminohydrolases - genetics | Multifunctional Enzymes - metabolism | Bone Neoplasms - pathology | Bone Neoplasms - metabolism | Proto-Oncogene Protein c-fli-1 - metabolism | HEK293 Cells | Minor Histocompatibility Antigens - genetics | Bone Neoplasms - genetics | Amino Acid Transport System ASC - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Sarcoma, Ewing - metabolism | Phosphoglycerate Dehydrogenase - metabolism | Proto-Oncogene Protein c-fli-1 - genetics | HCT116 Cells | RNA-Binding Protein EWS - genetics | Glycine - biosynthesis | Amino Acid Transport System ASC - metabolism | Multienzyme Complexes - genetics | RNA-Binding Protein EWS - metabolism | Phosphoglycerate Dehydrogenase - genetics | Formate-Tetrahydrofolate Ligase - metabolism | Minor Histocompatibility Antigens - metabolism | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Formate-Tetrahydrofolate Ligase - genetics | Aminohydrolases - metabolism | Sarcoma, Ewing - genetics | Glucose metabolism | International trade | Enzymes | Sarcoma | Analysis | Amino acids | Carbon cycle (Biogeochemistry) | Adolescence | Reactive oxygen species | Serine | DNA damage | Biosynthesis | Bone tumors | Glycine | Ewing's sarcoma | Proteins | Transcription activation | Adolescents | Redox properties | Damage accumulation | Deoxyribonucleic acid--DNA | Cell survival | Young adults | Risk groups | Metabolism | Nutrient uptake | Gene expression | Survival | Carbon cycle | Gene silencing | Adults | Transporter | Tumors | Apoptosis | Glutamine
Journal Article
Genes and Development, ISSN 0890-9369, 08/2018, Volume 32, Issue 15-16, pp. 1008 - 1019
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15, pp. 1688 - 1696
Journal Article
Nature, ISSN 0028-0836, 03/2018, Volume 555, Issue 7696, pp. 387 - 391
Journal Article
Journal Article
Annual Review of Pathology: Mechanisms of Disease, ISSN 1553-4006, 2012, Volume 7, Issue 1, pp. 145 - 159
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 08/2013, Volume 32, Issue 33, pp. 3915 - 3921
Ewing sarcoma is a pediatric bone tumor characterized in 85% of cases by the fusion between EWS and FLI1 genes that results in the expression of the EWS-FLI1... 
microRNAs | Ewing sarcoma | miR-30a-5p | EWS-FLI1 | CD99 | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | CANCER | CELL BIOLOGY | GENE | ONCOLOGY | MESENCHYMAL PROGENITOR CELLS | GENETICS & HEREDITY | SARCOMA CELLS | TRANSCRIPTION FACTOR | EXPRESSION | FUSION PROTEINS | Immunohistochemistry | Cell Adhesion Molecules - genetics | Oncogene Proteins, Fusion - metabolism | Oligonucleotide Array Sequence Analysis | Humans | MicroRNAs - metabolism | Transplantation, Heterologous | Antigens, CD - genetics | Antigens, CD - metabolism | Bone Neoplasms - metabolism | Flow Cytometry | Proto-Oncogene Protein c-fli-1 - metabolism | Bone Neoplasms - genetics | Gene Expression Regulation, Neoplastic - genetics | Sarcoma, Ewing - metabolism | Proto-Oncogene Protein c-fli-1 - genetics | RNA-Binding Protein EWS - genetics | Mice, SCID | RNA-Binding Protein EWS - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion Molecules - metabolism | Blotting, Western | 12E7 Antigen | Animals | Oncogene Proteins, Fusion - genetics | Fluorescent Antibody Technique | Cell Line, Tumor | Mice | MicroRNAs - genetics | Sarcoma, Ewing - genetics | Genes | Cancer cells | Physiological aspects | Genetic aspects | Research | Drug therapy | Ewing's sarcoma | Proteins | Bone cancer | Gene expression | Pathogenesis | MicroRNAs
Journal Article
Modern Pathology, ISSN 0893-3952, 09/2017, Volume 30, Issue 9, pp. 1312 - 1320
PAX7 is a paired-box transcription factor that is required for the developmental specification of adult skeletal muscle progenitors in mice. We previously... 
SYNOVIAL SARCOMA | FAMILY TRANSCRIPTION FACTOR | PRIMITIVE NEUROECTODERMAL TUMORS | CHROMOSOME-TRANSLOCATION | LYMPHOBLASTIC LYMPHOMA | GENE | ROUND-CELL SARCOMAS | FLI-1 | ANTIBODY | PATHOLOGY | IMMUNOHISTOCHEMICAL DETECTION | Immunohistochemistry | Oncogene Proteins, Fusion - metabolism | Oligonucleotide Array Sequence Analysis | United States | Humans | Gene Expression Regulation, Neoplastic | Sarcoma, Ewing - pathology | PAX7 Transcription Factor - genetics | PAX7 Transcription Factor - metabolism | Bone Neoplasms - pathology | Bone Neoplasms - metabolism | Chromatin Immunoprecipitation | Biomarkers, Tumor - metabolism | Transcription, Genetic | Bone Neoplasms - genetics | Acetylation | Sarcoma, Ewing - metabolism | RNA-Binding Protein EWS - genetics | Computational Biology | Chromatin Assembly and Disassembly | Gene Fusion | RNA-Binding Protein EWS - metabolism | Enhancer Elements, Genetic | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Protein Binding | Biomarkers, Tumor - genetics | High-Throughput Nucleotide Sequencing | Histones - metabolism | Sarcoma, Ewing - genetics | Translocation | Sarcoma | Histogenesis | Rhabdomyosarcoma | Genomes | Gene expression | Ribonucleic acid--RNA | FLI-1 protein | Ewing's sarcoma | Skeletal muscle | Musculoskeletal system | DNA microarrays | Stem cells | Fusion protein | Binding sites
Journal Article