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Journal of Biological Chemistry, ISSN 0021-9258, 07/2012, Volume 287, Issue 30, pp. 25530 - 25540
Fas is a member of the death receptor family. Stimulation of Fas leads to induction of apoptotic signals, such as caspase 8 activation, as well as... 
CD95 | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME | CANCER DEVELOPMENT | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | IN-VIVO | ALPHA-DEPENDENT APOPTOSIS | IKK-BETA | RECEPTOR | CELL-DEATH | Colonic Neoplasms - genetics | Fas Ligand Protein - metabolism | Humans | Caspase 8 - metabolism | Colonic Neoplasms - chemically induced | Neoplasms, Experimental - chemically induced | fas Receptor - metabolism | Promoter Regions, Genetic - genetics | Transcription Factor RelA - genetics | Colonic Neoplasms - metabolism | Embryo, Mammalian - metabolism | Caspase 8 - genetics | Sarcoma - chemically induced | NF-kappa B p52 Subunit - genetics | Tumor Suppressor Proteins - genetics | Neoplasms, Experimental - genetics | fas Receptor - genetics | Gene Expression Regulation, Neoplastic - drug effects | Sarcoma - genetics | Gene Expression Regulation, Neoplastic - genetics | Fibroblasts - metabolism | Tumor Suppressor Proteins - metabolism | Embryo, Mammalian - pathology | Fibroblasts - pathology | Sarcoma - pathology | Methylcholanthrene - toxicity | NF-kappa B p52 Subunit - metabolism | Mice, Knockout | Sarcoma - metabolism | Animals | Transcription Factor RelA - metabolism | Mice | Neoplasms, Experimental - metabolism | Fas Ligand Protein - genetics | Apoptosis | Index Medicus | Molecular Bases of Disease | Cancer Tumor Promoter | Fas | NF-kappaB Transcription Factor | NF-kappaB | Cancer
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1603 - 1619
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 6, pp. e10995 - e10995
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e61747 - e61747
Mitochondrial-nucleus cross talks and mitochondrial retrograde regulation can play a significant role in cellular properties. Transmitochondrial cybrid systems... 
BREAST-CANCER | APOPTOSIS | VITAMIN-E ANALOGS | PATHOGENIC MUTATIONS | MTDNA | TRANSMITOCHONDRIAL CYBRIDS | ANTICANCER AGENTS | MULTIDISCIPLINARY SCIENCES | DEPLETION | TUMORIGENESIS | DNA MUTATIONS | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Oligonucleotide Array Sequence Analysis | Hybrid Cells - drug effects | Humans | Cell Survival - genetics | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Cell Hypoxia | Neoplasm Metastasis | Cell Nucleus - metabolism | DNA, Mitochondrial - genetics | Heterografts | Mitochondria - genetics | Cell Transformation, Neoplastic - genetics | Adenosine Triphosphate - metabolism | Mammary Neoplasms, Experimental - pathology | Female | Hybrid Cells - metabolism | Cell Line | Cell Survival - drug effects | DNA, Mitochondrial - metabolism | Mitochondria - metabolism | Signal Transduction - genetics | Transcriptome - drug effects | Transcriptome - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Animals | Cell Nucleus - genetics | Mice, Nude | Cell Line, Tumor | Mice | Cell Transformation, Neoplastic - pathology | Doxorubicin - pharmacology | Care and treatment | DNA microarrays | Analysis | Genetic aspects | Mitochondrial DNA | B cells | Metastasis | Cancer | Cell proliferation | Cybrids | Epithelial cells | Genomics | Crosstalk | Childrens health | Reversing | Genomes | Cancer therapies | Nuclei | Anticancer properties | Metastases | Defects | Biomedical materials | Mitochondria | Pathways | Vitamin E | Osteosarcoma | DNA methylation | Genetics | Biocompatibility | Deoxyribonucleic acid--DNA | Benign | Agar | Oxygen consumption | Breast cancer | Gene expression | Medicine | Studies | Bone cancer | Chemotherapy | Epigenetics | Hypoxia | Nuclei (cytology) | Mutation | Electron transport | Viability | Apoptosis | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLOS GENETICS, ISSN 1553-7404, 04/2019, Volume 15, Issue 4, pp. e1008039 - e1008039
The SWI/SNF-family chromatin remodeling protein ATRX is a tumor suppressor in sarcomas, gliomas and other malignancies. Its loss of function facilitates the... 
TELOMERE MAINTENANCE | PATHWAY | XIST RNA | GENES | GENETICS & HEREDITY | PHENOTYPE | ACQUIRED ALPHA-THALASSEMIA | MUTATIONS | MYELODYSPLASTIC SYNDROME | EXPRESSION | TUMORS | Erythropoiesis | Loss of Function Mutation | Sarcoma, Experimental - metabolism | Humans | Male | Neurofibromin 1 - deficiency | Telomere Homeostasis - genetics | Zebrafish - embryology | Carcinogenesis - metabolism | X-linked Nuclear Protein - genetics | Tumor Suppressor Protein p53 - genetics | Female | X-linked Nuclear Protein - deficiency | Disease Models, Animal | Sarcoma, Experimental - etiology | Animals, Genetically Modified | Carcinogenesis - genetics | Gene Knockout Techniques | Tumor Suppressor Protein p53 - deficiency | Zebrafish - genetics | Sarcoma, Experimental - genetics | Globins - genetics | Zebrafish Proteins - deficiency | Animals | Zebrafish - metabolism | CRISPR-Cas Systems | Zebrafish Proteins - genetics | Neurofibromin 1 - genetics | Development and progression | Genetic aspects | Gene mutations | Sarcoma | Tumor proteins | Health aspects | Telomeres | Chromatin | RNA | Gliomas | Telomerase | Cancer | Visualization | Pediatrics | Funding | Intellectual disabilities | p53 Protein | Peripheral nerves | Oncology | Genomes | Carcinogenesis | Medical schools | DNA methylation | Bioinformatics | Chromosomes | Deoxyribonucleic acid--DNA | CRISPR | Phenotypes | Tumor cells | Zebrafish | Thalassemia | Ribonucleic acid--RNA | Gene expression | Chromatin remodeling | Polycomb group proteins | Gene silencing | Epigenetics | Tumor suppressor genes | Mutation | Tumors | Neuroendocrine tumors | Index Medicus | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Cancer Research, ISSN 0008-5472, 2009, Volume 69, Issue 7, pp. 2861 - 2869
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, pp. e0209941 - e0209941
Osteosarcoma (OSA) represents the most common primary bone tumor in humans and pet dogs. Little progress has been made with regard to viable treatment options... 
CELLS | INVASION | MIR-34A | METASTASIS | COMPARATIVE ONCOLOGY | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | RNA-DERIVED FRAGMENTS | PROLIFERATION | CANCER PROGRESSION | EXPRESSION | Osteosarcoma - drug therapy | Apoptosis - drug effects | Humans | Neoplasm Proteins - metabolism | Receptor, Platelet-Derived Growth Factor beta - genetics | MicroRNAs - pharmacology | Neoplasms, Experimental - pathology | RNA, Transfer - pharmacology | Neoplasms, Experimental - genetics | RNA, Transfer - genetics | Neoplasm Proteins - genetics | Osteosarcoma - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Notch1 - metabolism | Cell Lineage | Animals | Genetic Engineering | Dogs | MicroRNAs - genetics | Neoplasms, Experimental - metabolism | Osteosarcoma - genetics | Receptor, Notch1 - genetics | Neoplasms, Experimental - drug therapy | Prodrugs - pharmacology | Osteosarcoma - pathology | Bioengineering | Therapy | Veterinary colleges | Animal models | Xenotransplantation | Colorectal cancer | Bone tumors | Metastasis | Veterinary medicine | Cancer therapies | Necrosis | Cell adhesion & migration | Anticancer properties | Metastases | Proteins | Biomedical materials | Cell growth | Antitumor agents | Osteosarcoma | Xenografts | Cell cycle | Biocompatibility | Bones | Vascular endothelial growth factor | Growth factors | Wildlife conservation | tRNA | MiRNA | Gene expression | Ribonucleic acid--RNA | Patients | Pets | Bone cancer | MicroRNAs | Medical prognosis | Cell lines | Genetic engineering | Viability | Cell migration | Apoptosis | Tumors | Index Medicus | RNA | Ribonucleic acid
Journal Article
Journal Article