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SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 11
Site-directed methods for the generation of genetic diversity are essential tools in the field of directed enzyme evolution. The Golden Gate cloning technique... 
ENZYMES | MULTIDISCIPLINARY SCIENCES | LIBRARY | MUTATIONS | PROTEINS | DIRECTED EVOLUTION | SOFTWARE | Automation | Mutagenesis | Cloning | Amino acid sequence | Evolution | Genetic diversity | Saturation mutagenesis | Index Medicus
Journal Article
ChemBioChem, ISSN 1439-4227, 01/2016, Volume 17, Issue 1, pp. 56 - 64
l ‐Aspartate‐β‐semialdehyde dehydrogenase (ASADH) is a key enzyme in the aspartate pathway. In bacteria, ASADH is highly specific for the cofactor NADP +... 
oxidoreductases | enzyme catalysis | dehydrogenases | molecular modeling | iterative saturation mutagenesis
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, pp. 10654 - 10654
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 9/2018, Volume 102, Issue 18, pp. 7927 - 7934
Journal Article
IEEE/ACM Transactions on Computational Biology and Bioinformatics, ISSN 1545-5963, 07/2019, Volume 16, Issue 4, pp. 1143 - 1153
Journal Article
ChemBioChem, ISSN 1439-4227, 12/2018, Volume 19, Issue 24, pp. 2542 - 2544
A recent directed‐evolution study by Schwaneberg and co‐workers comparing the widely used iterative saturation mutagenesis (ISM) with the OmniChange version of... 
OmniChange | protein engineering | epistasis | iterative saturation mutagenesis | directed evolution | PATHWAYS | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCATALYSIS | LIBRARIES | ENZYMES | DNA | IMPROVEMENT | CREATION | OPTIMIZATION | PROTEINS | PCR | Enzymes | Randomization | Directed evolution | Mutagenesis | Workers | Saturation | Evolution | Selectivity | Saturation mutagenesis | Combinatorial analysis
Journal Article
Microbial cell factories, ISSN 1475-2859, 09/2018, Volume 17, Issue 1, pp. 141 - 141
Biosynthesis of steroidal drugs is of great benefit in pharmaceutical manufacturing as the process involves efficient enzymatic catalysis at ambient... 
3-ketosteroid | Rational design | Dehydrogenase | Saturation mutagenesis | Steered molecular dynamics | Substrate Specificity | Mutagenesis, Site-Directed - methods | Ketosteroids - metabolism | Oxidoreductases - metabolism | Biotransformation | Genetic aspects | Actinomycetes | Oxidoreductases | Gene mutations | Properties | Index Medicus
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 1/2018, Volume 102, Issue 2, pp. 733 - 742
Journal Article