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Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 1077
Our studies in HUVECs show that ox-LDL induced autophagy and damaged mtDNA leading to TLR9 expression. LOX-1 antibody or the ROS inhibitor apocynin attenuated... 
HEART | APOPTOSIS | ATHEROGENESIS | ARTERY ENDOTHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | DEGRADATION | OXIDIZED-LDL | LOX-1 | Human Umbilical Vein Endothelial Cells | Leukocyte Common Antigens - metabolism | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Toll-Like Receptor 9 - genetics | Autophagy - drug effects | Antigens, CD - metabolism | Inflammation - metabolism | RNA Interference | Diet, High-Fat | Endodeoxyribonucleases - metabolism | Receptors, LDL - deficiency | Beclin-1 | DNA Damage - drug effects | Receptors, LDL - genetics | Atherosclerosis - pathology | Endodeoxyribonucleases - antagonists & inhibitors | Scavenger Receptors, Class E - genetics | DNA, Mitochondrial - metabolism | Cells, Cultured | Lipoproteins, LDL - pharmacology | Receptors, LDL - metabolism | Atherosclerosis - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Scavenger Receptors, Class E - metabolism | Endodeoxyribonucleases - genetics | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Mice | Oxidative Stress - drug effects | Scavenger Receptors, Class E - deficiency | Toll-Like Receptor 9 - metabolism | RNA, Small Interfering - metabolism | Lipoproteins (low density) | Deoxyribonuclease | Oxidative stress | Reactive oxygen species | High cholesterol diet | DNA damage | siRNA | Mitochondrial DNA | Inflammation | LOX-1 protein | Autophagy | TLR9 protein | Cholesterol | CD45 antigen | Clonal deletion | Arteriosclerosis | Rodents | Atherosclerosis | Toll-like receptors | Lipoprotein (low density) receptors | Phagocytosis
Journal Article
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2018, Volume 114, Issue 8, pp. 1145 - 1153
Journal Article
Immunity, ISSN 1074-7613, 2005, Volume 22, Issue 5, pp. 551 - 560
Outer membrane protein A (OmpA) is a conserved major component of the outer membrane of . Here, we report that OmpA from (KpOmpA) activates macrophages and... 
C-REACTIVE PROTEIN | AMYLOID-P COMPONENT | DENDRITIC CELLS | MACROPHAGES | INFLAMMATION | ACUTE PHASE PROTEINS | TOLL-LIKE RECEPTORS | SCAVENGER RECEPTORS | DIFFERENTIATION | IMMUNOLOGY | LONG PENTRAXIN PTX3 | Toll-Like Receptor 2 | Dendritic Cells - immunology | Humans | Nerve Tissue Proteins - deficiency | Scavenger Receptors, Class F | Scavenger Receptors, Class E | C-Reactive Protein - metabolism | Transfection | C-Reactive Protein - deficiency | Receptors, Immunologic - immunology | CHO Cells | Recombinant Proteins - metabolism | Receptors, LDL - genetics | Cricetinae | Bacterial Outer Membrane Proteins - immunology | Klebsiella pneumoniae - immunology | Nerve Tissue Proteins - immunology | Signal Transduction | Receptors, Oxidized LDL | Mice, Inbred C57BL | Receptors, Immunologic - deficiency | Receptors, LDL - metabolism | C-Reactive Protein - genetics | Recombinant Proteins - genetics | Receptors, LDL - immunology | Immunity, Innate | Nerve Tissue Proteins - genetics | Macrophage Activation | Mice, Knockout | Nerve Tissue Proteins - metabolism | Models, Immunological | Animals | Receptors, Scavenger | Recombinant Proteins - immunology | Mice | In Vitro Techniques | Receptors, Immunologic - genetics | Immunity, Cellular | C-Reactive Protein - immunology | Receptors, Immunologic - metabolism | Medical colleges | Drug resistance in microorganisms | Pneumonia | Dendritic cells | Bacterial pneumonia | Antitank weapons | Proteins | Microorganisms | Statistical analysis | Bacteria | Ligands | Gram-negative bacteria | Immune system
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2013, Volume 169, Issue 8, pp. 1795 - 1809
Background and Purpose Atherosclerosis is associated with reduced vascular hydrogen sulfide (H2S) biosynthesis. GYY4137 is a novel slow-releasing H2S compound... 
arteriosclerosis | hydrogen sulfide | inflammation | endothelial dysfunction | oxidative stress | ACTIVATION | ATHEROSCLEROSIS | ISCHEMIA | VASORELAXANT | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | GENERATION | HYPERTENSION | NF-KAPPA-B | RECEPTOR-1 | Tumor Necrosis Factor-alpha - metabolism | Humans | Male | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Aorta - metabolism | Nitric Oxide Synthase Type II | Organothiophosphorus Compounds - pharmacology | Foam Cells - drug effects | Diet, High-Fat | Superoxides - metabolism | Female | Apolipoproteins E | Phosphorylation - drug effects | Interleukin-6 - metabolism | Scavenger Receptors, Class E - drug effects | NF-KappaB Inhibitor alpha | Atherosclerosis - drug therapy | Atherosclerosis - chemically induced | Down-Regulation | Cells, Cultured | I-kappa B Proteins | Morpholines - pharmacology | Cholesterol - metabolism | Atherosclerosis - metabolism | Scavenger Receptors, Class E - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Macrophages - metabolism | Animals | Endothelium, Vascular - metabolism | Macrophages - drug effects | Mice | Oxidative Stress - drug effects | Vascular Cell Adhesion Molecule-1 - metabolism | Hydrogen sulfide | RNA | Low density lipoproteins | Atherosclerosis | Lectins | Physiological aspects | Exhibitions | Acetylcholine | Superoxide | Cholesterol | Phosphorylation | Rodents | Endothelium | Research Papers
Journal Article
Immunity, ISSN 1074-7613, 10/2014, Volume 41, Issue 4, pp. 592 - 604
Journal Article