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Scientific Reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 1077
Our studies in HUVECs show that ox-LDL induced autophagy and damaged mtDNA leading to TLR9 expression. LOX-1 antibody or the ROS inhibitor apocynin attenuated... 
HEART | APOPTOSIS | ATHEROGENESIS | ARTERY ENDOTHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | DEGRADATION | OXIDIZED-LDL | LOX-1 | Human Umbilical Vein Endothelial Cells | Leukocyte Common Antigens - metabolism | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Toll-Like Receptor 9 - genetics | Autophagy - drug effects | Antigens, CD - metabolism | Inflammation - metabolism | RNA Interference | Diet, High-Fat | Endodeoxyribonucleases - metabolism | Receptors, LDL - deficiency | Beclin-1 | DNA Damage - drug effects | Receptors, LDL - genetics | Atherosclerosis - pathology | Endodeoxyribonucleases - antagonists & inhibitors | Scavenger Receptors, Class E - genetics | DNA, Mitochondrial - metabolism | Cells, Cultured | Lipoproteins, LDL - pharmacology | Receptors, LDL - metabolism | Atherosclerosis - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Scavenger Receptors, Class E - metabolism | Endodeoxyribonucleases - genetics | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Mice | Oxidative Stress - drug effects | Scavenger Receptors, Class E - deficiency | Toll-Like Receptor 9 - metabolism | RNA, Small Interfering - metabolism | Lipoproteins (low density) | Deoxyribonuclease | Oxidative stress | Reactive oxygen species | High cholesterol diet | DNA damage | siRNA | Mitochondrial DNA | Inflammation | LOX-1 protein | Autophagy | TLR9 protein | Cholesterol | CD45 antigen | Clonal deletion | Arteriosclerosis | Rodents | Atherosclerosis | Toll-like receptors | Lipoprotein (low density) receptors | Phagocytosis
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2013, Volume 169, Issue 8, pp. 1795 - 1809
Background and Purpose Atherosclerosis is associated with reduced vascular hydrogen sulfide (H2S) biosynthesis. GYY4137 is a novel slow‐releasing H2S compound... 
arteriosclerosis | hydrogen sulfide | inflammation | endothelial dysfunction | oxidative stress | ACTIVATION | ATHEROSCLEROSIS | ISCHEMIA | VASORELAXANT | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | GENERATION | HYPERTENSION | NF-KAPPA-B | RECEPTOR-1 | Tumor Necrosis Factor-alpha - metabolism | Humans | Male | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Aorta - metabolism | Nitric Oxide Synthase Type II | Organothiophosphorus Compounds - pharmacology | Foam Cells - drug effects | Diet, High-Fat | Superoxides - metabolism | Female | Apolipoproteins E | Phosphorylation - drug effects | Interleukin-6 - metabolism | Scavenger Receptors, Class E - drug effects | NF-KappaB Inhibitor alpha | Atherosclerosis - drug therapy | Atherosclerosis - chemically induced | Down-Regulation | Cells, Cultured | I-kappa B Proteins | Morpholines - pharmacology | Cholesterol - metabolism | Atherosclerosis - metabolism | Scavenger Receptors, Class E - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Macrophages - metabolism | Animals | Endothelium, Vascular - metabolism | Macrophages - drug effects | Mice | Oxidative Stress - drug effects | Vascular Cell Adhesion Molecule-1 - metabolism | Hydrogen sulfide | RNA | Low density lipoproteins | Atherosclerosis | Lectins | Physiological aspects | Exhibitions | Acetylcholine | Superoxide | Cholesterol | Phosphorylation | Rodents | Endothelium | Research Papers
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2018, Volume 114, Issue 8, pp. 1145 - 1153
Journal Article
FEBS Letters, ISSN 0014-5793, 2011, Volume 585, Issue 4, pp. 657 - 663
There is increasing evidence that microRNAs (miRNAs) play important roles in cell proliferation, apoptosis and differentiation that accompany inflammatory... 
Oxidized low density lipoprotein | Dendritic cell | Lipoprotein lipase | Immuno-inflammation | MicroRNA-29a | SRA | scavenger receptor A | dendritc cell | untranslated regions | oxidized low density lipoprotein | LPL | LOX-1 | UTR | TNF-α | tumor necrosis factor-α | lipoprotein lipase | lectin-like oxidized low-density lipoprotein receptor-1 | miRNA | microRNA | OxLDL | interleukin | OXIDATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPOPROTEIN-LIPASE | CELL BIOLOGY | HEART | PLAY | BIOPHYSICS | LDL | GENES | KEY ROLE | CD36 Antigens - genetics | MicroRNAs - antagonists & inhibitors | Dendritic Cells - immunology | Humans | MicroRNAs - metabolism | Molecular Targeted Therapy | RNA, Messenger - metabolism | Transfection | CD36 Antigens - metabolism | Dendritic Cells - drug effects | Scavenger Receptors, Class A - genetics | Lipoproteins, LDL - metabolism | 3' Untranslated Regions | Lipoprotein Lipase - metabolism | Dendritic Cells - metabolism | Genes, Reporter | Receptors, Scavenger - metabolism | Atherosclerosis - drug therapy | Atherosclerosis - immunology | Scavenger Receptors, Class E - genetics | Cytokines - metabolism | Oxidation-Reduction | Lipoprotein Lipase - genetics | Down-Regulation | Cells, Cultured | Cytokines - secretion | Gene Expression Regulation | Scavenger Receptors, Class E - metabolism | MicroRNAs - genetics | Scavenger Receptors, Class A - metabolism | Dendritic cells | Cytokines | Low density lipoproteins | Atherosclerosis | Cross infection | Nosocomial infections | MicroRNA | Lectins
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2011, Volume 184, Issue 1, pp. 82 - 91
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 6, pp. 1101 - 1113
Journal Article
Journal of neuropathology and experimental neurology, ISSN 0022-3069, 2013, Volume 72, Issue 2, pp. 106 - 118
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2012, Volume 32, Issue 9, pp. 2113 - 2121
OBJECTIVE—Cholesterol enrichment occurs in vivo when phagocytes ingest retained and aggregated lipoproteins, damaged or senescent cells, and related debris. We... 
endothelium | monocytes | cholesterol | microparticles | microvesicles | damage-associated molecular patterns | MACROPHAGE APOPTOSIS | LOW-DENSITY-LIPOPROTEIN | OXIDATION-SPECIFIC EPITOPES | ADHESION MOLECULES | DEFICIENT MICE | VASCULAR-DISEASE | INDUCED EXPRESSION | APOPTOTIC CELLS | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | TISSUE FACTOR | Injections, Intravenous | Human Umbilical Vein Endothelial Cells - metabolism | Cholesterol - administration & dosage | Coculture Techniques | Humans | Leukocyte Rolling | Monocytes - metabolism | NF-kappa B - metabolism | Monocytes - immunology | Aorta - metabolism | Superoxides - metabolism | Cell-Derived Microparticles - metabolism | Scavenger Receptors, Class E - genetics | Signal Transduction | Endothelial Cells - metabolism | Tissue Culture Techniques | Mice, Inbred C57BL | Cells, Cultured | Rats | Mitochondria - metabolism | Epitopes | Cholesterol - metabolism | Aryldialkylphosphatase - metabolism | Cell Adhesion | Cell Adhesion Molecules - metabolism | Rats, Sprague-Dawley | Hydrogen Peroxide - metabolism | Mice, Knockout | Endothelial Cells - immunology | Scavenger Receptors, Class E - metabolism | Venules - metabolism | Animals | Cell-Derived Microparticles - immunology | Electron Transport Complex II - metabolism | Mice | Scavenger Receptors, Class E - deficiency | Lipid Peroxidation | damage–associated molecular patterns
Journal Article