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Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6061, pp. 1372 - 1377
Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against... 
Schizonts | Malaria | RESEARCH ARTICLES | Liver | Antimalarials | Infections | Parasites | Inhibitory concentration 50 | Scaffolds | Blood | Chemicals | INFECTIONS | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | METHEMOGLOBINEMIA | RESISTANCE | MALARIA | TARGETS | MUTATIONS | Plasmodium berghei - physiology | Humans | Imidazoles - chemistry | Plasmodium - physiology | Piperazines - chemistry | Plasmodium falciparum - drug effects | Plasmodium - growth & development | Imidazoles - therapeutic use | Plasmodium falciparum - physiology | Antimalarials - pharmacokinetics | Antimalarials - therapeutic use | Imidazoles - pharmacology | Piperazines - therapeutic use | Random Allocation | Piperazines - pharmacology | Plasmodium berghei - cytology | Small Molecule Libraries | Malaria - parasitology | Cell Line, Tumor | Plasmodium berghei - growth & development | Mice | Mice, Inbred BALB C | Liver - parasitology | Erythrocytes - parasitology | Plasmodium berghei - drug effects | Plasmodium - cytology | Plasmodium falciparum - cytology | Plasmodium - drug effects | Imidazoles - pharmacokinetics | Plasmodium yoelii - growth & development | Protozoan Proteins - genetics | Sporozoites - growth & development | Protozoan Proteins - metabolism | Plasmodium yoelii - drug effects | Protozoan Proteins - chemistry | Molecular Structure | Piperazines - pharmacokinetics | Drug Evaluation, Preclinical | Sporozoites - drug effects | Drug Resistance | Plasmodium yoelii - physiology | Plasmodium yoelii - cytology | Drug Discovery | Antimalarials - pharmacology | Malaria - prevention & control | Animals | Antimalarials - chemistry | Polymorphism, Single Nucleotide | Malaria - drug therapy | Plasmodium falciparum - growth & development | Pharmaceutical research | Plasmodium | Care and treatment | Analysis | Research | Drug therapy
Journal Article
Journal Article
Science, ISSN 0036-8075, 5/2010, Volume 328, Issue 5980, pp. 910 - 912
Clinical malaria is associated with the proliferation of Plasmodium parasites in human erythrocytes. The coordinated processes of parasite egress from and... 
Proteins | Medical research | Schizonts | REPORTS | Erythrocytes | Erythrocyte invasion | Antibodies | Ligands | Gene expression regulation | Parasites | Merozoites | HOST-CELLS | MULTIDISCIPLINARY SCIENCES | CALCIUM | DEPENDENT PROTEIN-KINASE | MALARIA PARASITE | TOXOPLASMA-GONDII | EXPRESSION | Plasmodium falciparum - enzymology | Protein Kinases - metabolism | Protein Kinases - genetics | Schizonts - enzymology | Humans | Protein Kinases - chemistry | Plasmodium falciparum - cytology | Protozoan Proteins - genetics | Cyclic GMP-Dependent Protein Kinases - metabolism | Recombinant Fusion Proteins - metabolism | Schizonts - cytology | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Protozoan Proteins - metabolism | Protozoan Proteins - chemistry | Host-Parasite Interactions | Plasmodium falciparum - physiology | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Merozoites - physiology | Enzyme Inhibitors - pharmacology | Morpholines - metabolism | Merozoites - enzymology | Recombinant Fusion Proteins - chemistry | Pyrroles - pharmacology | Models, Biological | Pyridines - pharmacology | Plasmodium falciparum - growth & development | Schizonts - physiology | Erythrocytes - parasitology | Calcium-Binding Proteins - genetics | Physiological aspects | Plasmodium falciparum | Complications and side effects | Malaria | Health aspects | Biochemistry | Kinases | Protease | Replication | Egress
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 05/2013, Volume 48, Issue 5, pp. 589 - 600
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a deadly complication of malaria, and its pathophysiology is insufficiently understood.... 
Pulmonary inflammation | Plasmodium berghei NK65 | Malaria | Hemozoin | ARDS | ACTIVATION | FALCIPARUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | pulmonary inflammation | MONOCYTES | INJURY | HAEMOZOIN | malaria | CELL BIOLOGY | PLASMODIUM-VIVAX MALARIA | ERYTHROCYTES | RESPIRATORY SYSTEM | PIGMENT HEMOZOIN | MICE | GROWTH-FACTOR | hemozoin | Pneumonia - parasitology | Tumor Necrosis Factor-alpha - metabolism | Plasmodium berghei - immunology | Species Specificity | Plasmodium berghei - physiology | Humans | Tumor Necrosis Factor-alpha - genetics | Vascular Endothelial Growth Factor A - metabolism | Respiratory Distress Syndrome, Adult - metabolism | Vascular Endothelial Growth Factor A - genetics | Respiratory Distress Syndrome, Adult - etiology | Macrophages - parasitology | Plasmodium chabaudi - immunology | Schizonts - immunology | Plasmodium chabaudi - physiology | Interleukin-10 - metabolism | Pneumonia - immunology | Chemokine CCL2 - metabolism | Lung - metabolism | Host-Parasite Interactions | Malaria - metabolism | Gene Expression | Hemeproteins - metabolism | Lung - parasitology | Schizonts - metabolism | Mice, Inbred C57BL | Organ Size | Chemokine CCL2 - genetics | CD4 Lymphocyte Count | Plasmodium chabaudi - metabolism | Macrophages - metabolism | Plasmodium berghei - metabolism | Animals | Interleukin-10 - genetics | Erythrocytes - metabolism | Malaria - parasitology | Hemeproteins - physiology | Malaria - complications | Mice | Bronchoalveolar Lavage Fluid - chemistry | Schizonts - physiology | Erythrocytes - parasitology | Pneumonia - metabolism | Lung - immunology
Journal Article
Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5928, pp. 794 - 797
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e47557
Liver-stage malaria parasites are a promising target for drugs and vaccines against malaria infection. However, little is currently known about gene regulation... 
TRANSCRIPTION FACTORS | PARASITES | IMMUNITY | PROTECTION | MULTIDISCIPLINARY SCIENCES | INFECTIVITY | SPOROZOITES | SAP1 | PLASMODIUM-BERGHEI | T-CELLS | Liver - pathology | Plasmodium berghei - physiology | Trophozoites - metabolism | Humans | Plasmodium berghei - genetics | Molecular Sequence Data | Protozoan Proteins - genetics | Salivary Glands - parasitology | Hepatocytes - parasitology | Cell Nucleus - metabolism | Protozoan Proteins - metabolism | Female | Host-Parasite Interactions | Amino Acid Sequence | Gene Expression | Anopheles - parasitology | Schizonts - metabolism | Molecular Sequence Annotation | Gene Expression Regulation | Rats | Transcription Factors - genetics | Gene Knockout Techniques | Hep G2 Cells | Protein Transport | Transcription Factors - metabolism | Plasmodium berghei - metabolism | Trophozoites - physiology | Animals | Sporozoites - metabolism | Malaria - parasitology | Sporozoites - physiology | Mice | Mice, Inbred BALB C | Liver - parasitology | Schizonts - physiology | Infection | Plasmodium falciparum | DNA microarrays | Malaria | Liver | Malaria vaccine | Fluorescence | Amino acids | Genetic engineering | Vaccines | Health aspects | Membrane proteins | Drugs | Transcription factors | Zoology | Genomics | Gene regulation | Transgenic | Genomes | Infections | Parasites | Drug development | Aquatic insects | Parasitophorous vacuole | Proteins | Developmental stages | Sporozoites | Deoxyribonucleic acid--DNA | Vector-borne diseases | Antigens | Exploration | Gene expression | Medicine | Mosquitoes | Hepatocytes | Deoxyribonucleic acid | DNA
Journal Article
Malaria Journal, ISSN 1475-2875, 08/2017, Volume 16, Issue 1, pp. 305 - 11
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e76996 - e76996
Theileria equi has a biphasic life cycle in horses, with a period of intraleukocyte development followed by patent erythrocytic parasitemia that causes acute... 
BOVINE LYMPHOCYTES | SUSCEPTIBLE CATTLE | SEVERE COMBINED IMMUNODEFICIENCY | BOS-TAURUS | MULTIDISCIPLINARY SCIENCES | BABESIA-EQUI | HORSES | TICK BOOPHILUS-MICROPLUS | ANNULATA | MONOCLONAL-ANTIBODIES | PROTOZOAN PARASITE | Theileria annulata - immunology | Theileria - immunology | Species Specificity | Theileria - physiology | Lymphocytes - parasitology | T-Lymphocytes - parasitology | B-Lymphocytes - parasitology | Sporozoites - immunology | Macrophages - parasitology | Schizonts - immunology | Flow Cytometry | Lymphocytes - immunology | Leukocytes, Mononuclear - immunology | Severe Combined Immunodeficiency - blood | Macrophages - immunology | Erythrocytes - immunology | Theileriasis - immunology | Parasitemia - immunology | Theileriasis - parasitology | Theileria parva - immunology | Theileria parva - physiology | Leukocytes, Mononuclear - parasitology | Immunophenotyping | Host-Parasite Interactions - immunology | Severe Combined Immunodeficiency - immunology | Severe Combined Immunodeficiency - parasitology | Severe Combined Immunodeficiency - genetics | Animals | B-Lymphocytes - immunology | Horses | Parasitemia - parasitology | Sporozoites - physiology | T-Lymphocytes - immunology | Schizonts - physiology | Erythrocytes - parasitology | Microscopy, Fluorescence | Theileria annulata - physiology | Infection | B cells | Virulence (Microbiology) | T cells | Macrophages | Cell proliferation | Tropism | Flow cytometry | Severe combined immunodeficiency | Pathogenesis | Virulence | Animal diseases | Leukocytes (mononuclear) | Lymphocytes T | Infections | Leukocytes | Parasites | Kinases | Immunology | Cattle | Lymphocytes | Sporozoites | Life cycle engineering | Peripheral blood mononuclear cells | Parasitemia | Deoxyribonucleic acid--DNA | Antigens | Patents | Phenotypes | Immunoglobulins | Immune response | Gene expression | White blood cells | Pathology | Cytometry | Monocytes | Lymphocytes B | Microscopy | Morphology | Hemolytic disease | Laboratory animals | Immunofluorescence | Life cycles | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Malaria Journal, ISSN 1475-2875, 10/2017, Volume 16, Issue 1, pp. 409 - 12
Background: Evaluation of local Plasmodium falciparum malaria transmission has been investigated previously using the reversible catalytic model based on... 
SPOROZOITE | INFECTIOUS DISEASES | PERSISTENCE | ACQUISITION | INTENSITY | TROPICAL MEDICINE | RATES | PROTECTIVE IMMUNITY | COMMUNITY | ENDEMICITY | SURFACE-ANTIGENS | PARASITOLOGY | AGE | Models, Theoretical | Senegal - epidemiology | Prevalence | Age Factors | Cross-Sectional Studies | Humans | Male | Seroepidemiologic Studies | Endemic Diseases | Malaria, Falciparum - transmission | Antibodies, Protozoan - blood | Malaria, Falciparum - epidemiology | Female | Plasmodium falciparum - physiology | Schizonts - physiology | Longitudinal Studies | Viral antibodies | Plasmodium falciparum | Malaria | Antibodies | Physiological aspects | Development and progression | Models | Properties | Health aspects | Risk factors | Endemic species | Disease | Transmission | Insecticides | Infections | Parasites | Epidemiology | Tropical diseases | Inoculation | Control | Mathematical models | Modelling | Longitudinal studies | Rainy season | Public health | Age | Enzyme-linked immunosorbent assay | Vector-borne diseases | Antigens | Evaluation | Human diseases | Immunoglobulins | Schizonts | Rural areas | Mortality | Data | Surveying | Seroconversion | Strain | Studies | Surveys | Disease transmission | Malaria, Falciparum/transmission | Applications | Statistics | Life Sciences | Antibodies, Protozoan/blood | Schizonts/physiology | Santé publique et épidémiologie | Plasmodium falciparum/physiology | Malaria, Falciparum/epidemiology | Senegal/epidemiology
Journal Article