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Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 50 - 54
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by... 
CRB2 | RECRUITMENT | FISSION YEAST | METHYLATION | CHROMATIN | DEPENDENT RESPONSE | RESECTION | MULTIDISCIPLINARY SCIENCES | SITES | DOUBLE-STRAND BREAKS | CLASS-SWITCH RECOMBINATION | Schizosaccharomyces pombe Proteins - chemistry | Histones - chemistry | Nucleosomes - chemistry | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - deficiency | Cell Cycle Proteins - chemistry | Intracellular Signaling Peptides and Proteins - deficiency | Ubiquitination | Schizosaccharomyces pombe Proteins - metabolism | Female | Lysine - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Schizosaccharomyces | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Signal Transduction | Cell Cycle Proteins - metabolism | Nucleosomes - metabolism | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - deficiency | Amino Acid Motifs | Chromosomal Proteins, Non-Histone - genetics | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Mutant Proteins - chemistry | Protein Binding | Mice | DNA Damage | Histones - metabolism | Tumor Suppressor p53-Binding Protein 1 | Chromosomal Proteins, Non-Histone - chemistry | Ubiquitin | Research | Properties | DNA repair | DNA damage | Proteins | DNA methylation | Mutation | Experiments | Recruitment | Index Medicus
Journal Article
Journal Article
Cell, ISSN 0092-8674, 03/2007, Volume 128, Issue 6, pp. 1063 - 1076
Methylation of histones has been regarded as a stable modification defining the epigenetic program of the cell, which regulates chromatin structure and... 
DOMAIN-CONTAINING PROTEINS | METHYLATION | CAENORHABDITIS-ELEGANS | METHYLTRANSFERASE | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCAPES X-INACTIVATION | TRITHORAX | RETINOBLASTOMA-BINDING PROTEIN-2 | TRANSCRIPTIONAL REGULATION | CELL BIOLOGY | Caenorhabditis elegans Proteins - chemistry | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Phylogeny | Gene Deletion | Tumor Suppressor Proteins - chemistry | Oxidoreductases, N-Demethylating - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Repressor Proteins - metabolism | Amino Acid Sequence | Tumor Suppressor Proteins - metabolism | Repressor Proteins - genetics | Caenorhabditis elegans - embryology | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Histone Demethylases | Lysine | Drosophila melanogaster - enzymology | Schizosaccharomyces - enzymology | Mice | Histones - metabolism | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Embryonic Stem Cells - metabolism | Oxidoreductases, N-Demethylating - genetics | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Tumor Suppressor Proteins - genetics | Carrier Proteins - chemistry | Nuclear Proteins - genetics | Genes, Homeobox | Protein Structure, Tertiary | Repressor Proteins - chemistry | Embryonic Stem Cells - enzymology | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Oxidoreductases, N-Demethylating - chemistry | Proteins - genetics | Carrier Proteins - genetics | Sequence Alignment | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Intracellular Signaling Peptides and Proteins - chemistry | Retinoblastoma-Binding Protein 2 | Proteins - chemistry | Methylation | Jumonji Domain-Containing Histone Demethylases | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 248 - 251
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 688 - 703
Covalent DNA-protein crosslinks (DPCs) are toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription.... 
DVC1 | progeria | protease | formaldehyde | Spartan | Wss1 | Ruijs-Aalfs syndrome | SPRTN | topoisomerase | DNA-protein crosslinks | DNA repair | hepatocellular carcinoma | GENOMIC INSTABILITY | CELLS | DAMAGE RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPARTAN/C1ORF124 | DVC1 C1ORF124 | FANCONI-ANEMIA | HELICASE | NUCLEOTIDE EXCISION-REPAIR | CELL BIOLOGY | Schizosaccharomyces pombe Proteins - chemistry | Fibroblasts - enzymology | Formaldehyde - chemistry | Caenorhabditis elegans Proteins - chemistry | Humans | Caenorhabditis elegans Proteins - metabolism | Substrate Specificity | Crystallography, X-Ray | DNA-Binding Proteins - metabolism | Schizosaccharomyces - genetics | Cisplatin - chemistry | Ultraviolet Rays | Schizosaccharomyces pombe Proteins - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Amino Acid Sequence | Cell Line | Xeroderma Pigmentosum Group A Protein - metabolism | Cross-Linking Reagents - chemistry | Schizosaccharomyces pombe Proteins - genetics | Protein Structure, Secondary | Caenorhabditis elegans - genetics | Xeroderma Pigmentosum Group A Protein - genetics | Models, Molecular | DNA - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Caenorhabditis elegans - radiation effects | Xeroderma Pigmentosum Group A Protein - chemistry | DNA - genetics | Sequence Homology, Amino Acid | DNA - chemistry | Sequence Alignment | Animals | Caenorhabditis elegans - drug effects | Fibroblasts - radiation effects | DNA Repair | Fibroblasts - drug effects | Protein Binding | Schizosaccharomyces - enzymology | Fibroblasts - cytology | Mice | HeLa Cells | Kinetics | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Ubiquitin | Chromatin | Proteases | DNA | Genetic research | Genetic transcription | Molecular biology | Formaldehyde | Index Medicus | BASIC BIOLOGICAL SCIENCES | protease Ruijs-Aalfs syndrome
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2004, Volume 279, Issue 49, pp. 50994 - 51001
Journal Article
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7393, pp. 208 - 213
In mitosis, the spindle assembly checkpoint (SAC) ensures genome stability by delaying chromosome segregation until all sister chromatids have achieved bipolar... 
ANAPHASE-PROMOTING COMPLEX | FISSION YEAST | KEN BOX | BUDDING YEAST | PROTEIN BUBR1 | MULTIDISCIPLINARY SCIENCES | PSEUDOSUBSTRATE INHIBITION | DESTRUCTION BOX | SACCHAROMYCES-CEREVISIAE | MAD2 ACTIVATION | SPINDLE-ASSEMBLY CHECKPOINT | Anaphase-Promoting Complex-Cyclosome | Schizosaccharomyces pombe Proteins - chemistry | M Phase Cell Cycle Checkpoints | Schizosaccharomyces - chemistry | Humans | Ubiquitin-Protein Ligase Complexes - antagonists & inhibitors | Substrate Specificity | Crystallography, X-Ray | Structure-Activity Relationship | Spindle Apparatus | Cell Cycle Proteins - chemistry | Multiprotein Complexes - metabolism | Cdh1 Proteins | Protein Structure, Quaternary | Schizosaccharomyces pombe Proteins - metabolism | Conserved Sequence | Mad2 Proteins | Cdc20 Proteins | Protein Structure, Tertiary | Cell Cycle Proteins - metabolism | Models, Molecular | Nuclear Proteins - metabolism | Saccharomyces cerevisiae Proteins - genetics | Nuclear Proteins - chemistry | Ubiquitin-Protein Ligase Complexes - chemistry | Amino Acid Motifs | Multiprotein Complexes - chemistry | Ubiquitin-Protein Ligase Complexes - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Ubiquitin-Protein Ligase Complexes - ultrastructure | Proteins | Kinases | Binding sites | Crystal structure | Index Medicus
Journal Article
Dalton Transactions, ISSN 1477-9226, 10/2018, Volume 47, Issue 40, pp. 14241 - 14253
Journal Article
Journal Article
PLoS Biology, ISSN 1544-9173, 06/2009, Volume 7, Issue 6, pp. e1000134 - e1000134
Journal Article