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Journal Article
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 12/2007, Volume 293, Issue 6, pp. 1645 - 1655
Evidence for important roles of the highly reactive oxidant peroxynitrite in diabetic complications is emerging. We evaluated the role of peroxynitrite in... 
OXIDATIVE STRESS | PHYSIOLOGY | POLY(ADP-RIBOSE) POLYMERASE ACTIVATION | ENDOTHELIAL DYSFUNCTION | EPINEURIAL ARTERIOLES | ENDOCRINOLOGY & METABOLISM | ALDOSE REDUCTASE INHIBITION | NERVE CONDUCTION-VELOCITY | ANTIOXIDANT TREATMENT | PERIPHERAL NEUROPATHY | PEROXYNITRITE DECOMPOSITION CATALYST | ENDONEURIAL BLOOD-FLOW | Mesenteric Arteries - physiopathology | Rats, Wistar | Coronary Vessels - physiopathology | Body Weight - drug effects | Male | Mesenteric Arteries - drug effects | Sciatic Nerve - physiopathology | Aorta - metabolism | Metalloporphyrins - pharmacology | Tyrosine - analogs & derivatives | Diabetic Angiopathies - physiopathology | Metalloporphyrins - therapeutic use | Sciatic Nerve - metabolism | Regional Blood Flow - drug effects | Arterioles - physiopathology | Superoxides - metabolism | Neural Conduction - drug effects | Peroxynitrous Acid - antagonists & inhibitors | Sciatic Nerve - drug effects | Diabetes Mellitus, Experimental - metabolism | Diabetes Mellitus, Experimental - physiopathology | Diabetic Neuropathies - physiopathology | Hypoglycemic Agents - therapeutic use | Diabetic Angiopathies - metabolism | Coronary Vessels - drug effects | Vasodilator Agents - pharmacology | Hyperalgesia - metabolism | Rats | Diabetic Neuropathies - drug therapy | Diabetic Angiopathies - drug therapy | Hyperalgesia - physiopathology | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Poly Adenosine Diphosphate Ribose - metabolism | Tyrosine - metabolism | Animals | Arterioles - metabolism | Peroxynitrous Acid - metabolism | Diabetic Neuropathies - metabolism | Ganglia, Spinal - metabolism
Journal Article
Experimental Neurology, ISSN 0014-4886, 12/2011, Volume 232, Issue 2, pp. 154 - 161
Journal Article
Journal of Neurology, Neurosurgery and Psychiatry, ISSN 0022-3050, 2018, Volume 90, Issue 4, pp. 424 - 427
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 03/2013, Volume 62, Issue 3, pp. 944 - 952
Endoplasmic reticulum stress resulting from abnormal folding of newly synthesized proteins impairs metabolism, transcriptional regulation, and gene expression,... 
APOPTOSIS | ACTIVATION | LIPOIC ACID | CONDUCTION-VELOCITY | CALCIUM | ENDOCRINOLOGY & METABOLISM | ANTIOXIDANT TREATMENT | REDUCES OXIDATIVE STRESS | NERVE-FIBER LOSS | BLOOD-FLOW | MANIFESTATIONS | Phenylbutyrates - therapeutic use | Spinal Cord - drug effects | Spinal Cord - metabolism | Diabetic Neuropathies - etiology | Rats, Wistar | Streptozocin | Male | Sciatic Nerve - physiopathology | Molecular Targeted Therapy | Sciatic Nerve - blood supply | Sciatic Nerve - metabolism | Sciatic Nerve - drug effects | CCAAT-Enhancer-Binding Proteins - genetics | Methylamines - therapeutic use | Epidermis - innervation | Diabetic Neuropathies - physiopathology | CCAAT-Enhancer-Binding Proteins - metabolism | Epidermis - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Unfolded Protein Response - drug effects | Epidermis - pathology | Endoplasmic Reticulum Stress - drug effects | Epidermis - drug effects | Mice, Inbred C57BL | Rats | Mice, Transgenic | Diabetic Neuropathies - drug therapy | Random Allocation | Spinal Cord - blood supply | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Up-Regulation - drug effects | Animals | Mice | Spinal Cord - physiopathology | Diabetic Neuropathies - metabolism | Development and progression | Research | Polyneuropathies | Endoplasmic reticulum | Analysis | Complications
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2015, Volume 764, pp. 599 - 606
Journal Article
Molecular Pain, ISSN 1744-8069, 4/2011, Volume 7, Issue 1, pp. 29 - 29
Background: A major clinical issue affecting 10-40% of cancer patients treated with oxaliplatin is severe peripheral neuropathy with symptoms including cold... 
Electrophysiology | Oxaliplatin peripheral neuropathy | Spinal dorsal horn | Dorsal root ganglia | Cold hyperalgesia | Mechanical allodynia | cold hyperalgesia | PRIMARY AFFERENT NEURONS | MULTICENTER PHASE-II | NEUROTROPHIC FACTOR | dorsal root ganglia | DORSAL-ROOT GANGLION | NEUROSCIENCES | METASTATIC COLORECTAL-CANCER | SENSORY NEURONS | electrophysiology | IN-VIVO | DIFFERENT SCHEDULES | mechanical allodynia | INDUCED NEUROTOXICITY | spinal dorsal horn | Posterior Horn Cells - drug effects | Peripheral Nervous System Diseases - chemically induced | Body Weight - drug effects | Sciatic Nerve - physiopathology | Ganglia, Spinal - physiopathology | Peripheral Nervous System Diseases - physiopathology | Pain - chemically induced | Hyperalgesia - pathology | Organoplatinum Compounds - administration & dosage | Pain - complications | Cell Nucleolus - metabolism | Cell Nucleolus - drug effects | Female | Posterior Horn Cells - physiopathology | Neural Conduction - drug effects | Peripheral Nervous System Diseases - pathology | Sciatic Nerve - drug effects | Peripheral Nervous System Diseases - complications | Sciatic Nerve - pathology | Hyperalgesia - complications | Axons - drug effects | Rats | Pain - pathology | Hyperalgesia - physiopathology | Animals | Pain - physiopathology | Axons - pathology | Ganglia, Spinal - pathology | Posterior Horn Cells - pathology | Mice | Mice, Inbred BALB C | Ganglia, Spinal - drug effects | Organoplatinum Compounds - therapeutic use | Organoplatinum Compounds - adverse effects | Chemotherapy | Polyneuropathies | Colorectal cancer | Research | Drug therapy | Health aspects | Risk factors | Cancer | Index Medicus | Oxaliplatin | peripheral neuropathy
Journal Article
Anaesthesia, ISSN 0003-2409, 09/2018, Volume 73, Issue 9, pp. 1110 - 1117
Summary Animal data have demonstrated increased block duration after local anaesthetic injections in diabetic rat models. Whether the same is true in humans is... 
diabetes mellitus | analgesia | peripheral nerve block | METAANALYSIS | BRACHIAL-PLEXUS BLOCKADE | REGIONAL ANESTHESIA | PERINEURAL DEXAMETHASONE | TOTAL KNEE ARTHROPLASTY | PROLONG ANALGESIA | SCIATIC-NERVE | ULTRASOUND | ANESTHESIOLOGY | FATTY RATS | ANALGESIC EFFICACY | Prospective Studies | Humans | Middle Aged | Ultrasonography, Interventional | Male | Sciatic Nerve - physiopathology | Nerve Block - methods | Anesthetics, Local - pharmacology | Case-Control Studies | Young Adult | Time Factors | Aged, 80 and over | Adult | Female | Sciatic Nerve - diagnostic imaging | Sciatic Nerve - drug effects | Anesthetics, Local - administration & dosage | Diabetes Mellitus, Type 2 - complications | Diabetic Foot - physiopathology | Drug Administration Schedule | Diabetic Foot - surgery | Diabetic Foot - etiology | Pain, Postoperative - prevention & control | Sensation - drug effects | Foot - surgery | Pain Measurement - methods | Diabetes Mellitus, Type 2 - physiopathology | Analgesics, Opioid - administration & dosage | Aged | Comparative analysis | Diabetics | Diabetic foot | Animal models | Narcotics | Diabetes mellitus | Diabetic neuropathy | Regression analysis | Peripheral neuropathy | Patients | Regression models | Ultrasonic imaging | Bupivacaine | Pain | Surgery | Failure analysis | Opioids | Diabetes | Lidocaine | Health risk assessment | Ultrasound | Sciatic nerve
Journal Article