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1. Full Text Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: Conformation, selectin binding, and biological activity
by Panagos, Charalampos G and Thomson, Derek S and Moss, Claire and Hughes, Adam D and Kelly, Maeve S and Liu, Yan and Chai, Wengang and Venkatasamy, Radhakrishnan and Spina, Domenico and Page, Clive P and Hogwood, John and Woods, Robert J and Mulloy, Barbara and Bavington, Charlie D and Uhrín, Dušan
Journal of Biological Chemistry, ISSN 0021-9258, 10/2014, Volume 289, Issue 41, pp. 28284 - 28298
Fucosylated chondroitin sulfate (fCS) extracted from the sea cucumber Holothuria forskali is composed of the following repeating trisaccharide unit: ->... 
RESIDUAL DIPOLAR COUPLINGS | FREE-RADICAL DEPOLYMERIZATION | NMR-SPECTROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | LEWIS-X | HUMAN-LEUKOCYTE ELASTASE | P-SELECTIN | ANTICOAGULANT ACTIVITIES | HEPARAN-SULFATE | MOLECULAR-DYNAMICS SIMULATIONS | STICHOPUS-JAPONICUS | Leukocyte Elastase - metabolism | Sea Cucumbers - chemistry | Chondroitin Sulfates - metabolism | P-Selectin - metabolism | Hydrogen Peroxide | Proteinase Inhibitory Proteins, Secretory - metabolism | Molecular Sequence Data | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Iron | Proteinase Inhibitory Proteins, Secretory - chemistry | Anti-Inflammatory Agents, Non-Steroidal - isolation & purification | Leukocyte Elastase - antagonists & inhibitors | Leukocyte Disorders - metabolism | P-Selectin - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | L-Selectin - metabolism | Immune System Diseases - metabolism | Peritonitis - pathology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Immune System Diseases - pathology | Neutrophils - metabolism | Neutrophil Infiltration - drug effects | Neutrophils - pathology | Oxidation-Reduction | Neutrophils - drug effects | Peritonitis - metabolism | Models, Molecular | Chondroitin Sulfates - isolation & purification | Immune System Diseases - drug therapy | Leukocyte Disorders - pathology | Proteinase Inhibitory Proteins, Secretory - isolation & purification | Chondroitin Sulfates - pharmacology | Chondroitin Sulfates - chemistry | Leukocyte Disorders - drug therapy | Proteinase Inhibitory Proteins, Secretory - pharmacology | Animals | L-Selectin - chemistry | Mice | Peritonitis - drug therapy | Carbohydrate Conformation | Carbohydrate-binding Protein | Selectin | Molecular Dynamics | Glycosaminoglycan | Glycobiology and Extracellular Matrices | Inflammation | Microarray | GAG | Carbohydrate Structure | Nuclear Magnetic Resonance (NMR)
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2. Full Text Fucosylated chondroitin sulfate diversity in sea cucumbers: A review
by Myron, Pang and Siddiquee, Shafiquzzaman and Al Azad, Sujjat
Carbohydrate Polymers, ISSN 0144-8617, 11/2014, Volume 112, pp. 173 - 178
Fucosylated chondroitin sulfate (FucCS) is structurally distinct glycosaminoglycans found from the sea cucumber body wall consisted of chondroitin sulfate type... 
Sulfated glycosaminoglycans | Chondroitin sulfate | Structure | Holothurians | Fucose | PHYSICOCHEMICAL CHARACTERISTICS | FUCOSE BRANCHES | ACTIVATION | POLYMER SCIENCE | FREE-RADICAL DEPOLYMERIZATION | MUSCLE | RATS | CHEMISTRY, ORGANIC | ANTICOAGULANT ACTIVITIES | CHEMISTRY, APPLIED | GLYCOSAMINOGLYCAN | BODY-WALL | POLYSACCHARIDE | Carbohydrate Sequence | Sea Cucumbers - chemistry | Molecular Sequence Data | Animals | Chondroitin Sulfates - metabolism | Chondroitin Sulfates - chemistry | Sulfates | Chondroitin
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3. Full Text Structure, absolute configuration, and conformational study of 12-membered macrolides from the fungus dendrodochium sp. associated with the sea cucumber holothuria nobilis selenka
by Sun, Peng and Xu, Dong-Xiao and Mándi, Attila and Kurtán, Tibor and Li, Tie-Jun and Schulz, Barbara and Zhang, Wen
Journal of Organic Chemistry, ISSN 0022-3263, 07/2013, Volume 78, Issue 14, pp. 7030 - 7047
Dendrodolides A-M (1-13), 13 new 12-membered macrolides, were isolated from Dendrodochium sp., a fungus associated with the sea cucumber Holothuria nobilis... 
ENDOPHYTIC FUNGUS | CHEMOENZYMATIC TOTAL-SYNTHESIS | POLYKETIDE METABOLITES | PATULOLIDE-A | (+/-)-PATULOLIDE C | CHEMISTRY, ORGANIC | (+)-PATULOLIDE C | STEREOSELECTIVE-SYNTHESIS | ISO-CLADOSPOLIDE-B | CONVERGENT SYNTHESIS | ENANTIOSELECTIVE TOTAL-SYNTHESIS | Mitosporic Fungi - chemistry | Sea Cucumbers - chemistry | Animals | Macrolides - isolation & purification | Macrolides - chemistry | Molecular Conformation | Models, Molecular | Crystallography, X-Ray | Molecular Structure | Density functionals | Usage | X-ray spectroscopy | Methods | Conformational analysis
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4. Full Text Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers
by Luo, Lan and Wu, Mingyi and Xu, Li and Lian, Wu and Xiang, Jingying and Lu, Feng and Gao, Na and Xiao, Chuang and Wang, Shengmin and Zhao, Jinhua
Marine Drugs, ISSN 1660-3397, 02/2013, Volume 11, Issue 2, pp. 399 - 417
In order to search for sulfated polysaccharides in different invertebrate connective tissues and to examine their biological activities, we have isolated three... 
Glucan | Sulfated fucan | Sea cucumber | Polysaccharide | Anticoagulant activity | Fucosylated chondroitin sulfate | CHEMISTRY, MEDICINAL | MOLECULAR-WEIGHT FRACTIONS | polysaccharide | FREE-RADICAL DEPOLYMERIZATION | anticoagulant activity | fucosylated chondroitin sulfate | glucan | THELENATA-ANANAS | HEPARIN | STICHOPUS-JAPONICUS | sulfated fucan | PERFORMANCE LIQUID-CHROMATOGRAPHY | FUCANS | sea cucumber | GLYCOSAMINOGLYCAN | BODY-WALL | Sea Cucumbers - chemistry | Animals | Anticoagulants - chemistry | Anticoagulants - pharmacology | Polysaccharides - chemistry | Structure-Activity Relationship | Polysaccharides - pharmacology
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5. Full Text Cladolosides I 1 , I 2 , J 1 , K 1 , K 2 and L 1, monosulfated triterpene glycosides with new carbohydrate chains from the sea cucumber Cladolabes schmeltzii
by Silchenko, Alexandra S and Kalinovsky, Anatoly I and Avilov, Sergey A and Andryjaschenko, Pelageya V and Dmitrenok, Pavel S and Chingizova, Ekaterina A and Dolmatov, Igor Yu and Kalinin, Vladimir I
Carbohydrate research, ISSN 0008-6215, 06/2017, Volume 445, pp. 80 - 87
Six new monosulfated triterpene glycosides, cladolosides I (1), I (2), J (3), K (4), K (5) and L (6) were isolated from the tropical Indo-West Pacific sea... 
Sea Cucumbers - chemistry | Triterpenes - chemistry | Animals | Glycosides - chemistry | Sulfates - chemistry
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6. Full Text A highly regular fucosylated chondroitin sulfate from the sea cucumber Massinium magnum: Structure and effects on coagulation
by Ustyuzhanina, Nadezhda E and Bilan, Maria I and Dmitrenok, Andrey S and Borodina, Elizaveta Yu and Stonik, Valentin A and Nifantiev, Nikolay E and Usov, Anatolii I
Carbohydrate Polymers, ISSN 0144-8617, 07/2017, Volume 167, pp. 20 - 26
A fucosylated chondroitin sulfate was isolated from the sea cucumber . Structure of this polysaccharide was determined using chemical and NMR spectroscopic... 
Sea cucumber | Anticoagulant | Massinium magnum | Structure | Fucosylated chondroitin sulfate | POLYMER SCIENCE | CHEMISTRY, ORGANIC | GLYCOSYLATION | FRAGMENTS | JAPONICUS | BIOLOGICAL-ACTIVITY | POLYSACCHARIDES | FUCOIDAN | ALGAE | ANTICOAGULANT ACTIVITY | CHEMISTRY, APPLIED | ANTITHROMBOTIC ACTIVITIES | Sea Cucumbers - chemistry | Animals | Blood Coagulation - drug effects | Humans | Platelet Aggregation - drug effects | Chondroitin Sulfates - chemistry | Fucose | Thrombin Time | Sulfates | Chondroitin | Thrombin | Anticoagulants (Medicine)
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7. Full Text Contributions of molecular size, charge distribution, and specific amino acids to the iron-binding capacity of sea cucumber (Stichopus japonicus) ovum hydrolysates
by Sun, Na and Cui, Pengbo and Jin, Ziqi and Wu, Haitao and Wang, Yixing and Lin, Songyi
Food Chemistry, ISSN 0308-8146, 09/2017, Volume 230, pp. 627 - 636
This study investigated the contributions of molecular size, charge distribution and specific amino acids to the iron-binding capacity of sea cucumber ( ) ovum... 
Characterization | Amino acids | Molecular size | Iron binding | Sea cucumber ovum | PROTEIN | MECHANISM | FOOD SCIENCE & TECHNOLOGY | MEAL | WHEY | DEFICIENCY | NUTRITION & DIETETICS | FRACTIONS | CHELATING PEPTIDES | ANTIOXIDANT | PURIFICATION | SEPARATION | CHEMISTRY, APPLIED | Sea Cucumbers - chemistry | Ovum - chemistry | Iron-Binding Proteins - chemistry | Animals | Iron - chemistry | Amino Acids | Hydrolysis | Enzymes | Aspartate | Peptides | Nitrogen | Analysis | High performance liquid chromatography
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8. Full Text Two fucosylated chondroitin sulfates from the sea cucumber Eupentacta fraudatrix
by Ustyuzhanina, Nadezhda E and Bilan, Maria I and Dmitrenok, Andrey S and Nifantiev, Nikolay E and Usov, Anatolii I
Carbohydrate Polymers, ISSN 0144-8617, 05/2017, Volume 164, pp. 8 - 12
Two fucosylated chondroitin sulfates and were isolated from the sea cucumber . Separation of the polysaccharides was performed using anion-exchange... 
Anion-exchange chromatography | Sea cucumber | NMR | Eupentacta fraudatrix | Fucosylated chondroitin sulfate | BRANCH | POLYMER SCIENCE | CHEMISTRY, ORGANIC | GLYCOSYLATION | STICHOPUS-JAPONICUS | BIOLOGICAL-ACTIVITY | POLYSACCHARIDES | FUCOIDAN | ANTICOAGULANT ACTIVITIES | CHEMISTRY, APPLIED | APOSTICHOPUS-JAPONICUS | GLYCOSAMINOGLYCAN | BODY-WALL | Sea Cucumbers - chemistry | Chondroitin Sulfates - isolation & purification | Animals | Chondroitin Sulfates - chemistry | Magnetic Resonance Spectroscopy | Disaccharides - chemistry | Sulfates | Nuclear magnetic resonance spectroscopy | Chondroitin | Chromatography
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9. Full Text Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber: Effect on tumor metastasis and neutrophil recruitment
by Borsig, Lubor and Wang, Lianchun and Cavalcante, Moises C. M and Cardilo-Reis, Larissa and Ferreira, Paola L and Mourão, Paulo A. S and Esko, Jeffrey D and Pavão, Mauro S. G
Journal of Biological Chemistry, ISSN 0021-9258, 05/2007, Volume 282, Issue 20, pp. 14984 - 14991
Heparin is an excellent inhibitor of P- and L-selectin binding to the carbohydrate determinant, sialyl Lewisx. As a consequence of its anti-selectin activity,... 
CARCINOMA MUCINS | LIGANDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | P-SELECTIN | LUNG COLONIZATION | CELL-ADHESION | COLON | HEPARIN | CANCER | PLATELET-AGGREGATING ACTIVITIES | Sea Cucumbers - chemistry | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | P-Selectin - metabolism | Lung Neoplasms - metabolism | Pneumonia - pathology | Heparin - therapeutic use | Lung Neoplasms - pathology | Thioglycolates - toxicity | L-Selectin - metabolism | Dose-Response Relationship, Drug | Neoplasms, Experimental - pathology | Peritonitis - pathology | Neoplasm Metastasis | Adenocarcinoma - metabolism | Lung Neoplasms - secondary | Pneumonia - chemically induced | Heparin - pharmacology | Neutrophil Infiltration - drug effects | Disease Models, Animal | Lipopolysaccharides - toxicity | Peritonitis - metabolism | Anticoagulants - therapeutic use | Chondroitin Sulfates - pharmacology | Peritonitis - chemically induced | Chondroitin Sulfates - chemistry | Cell Adhesion - drug effects | Chondroitin Sulfates - therapeutic use | Adenocarcinoma - drug therapy | Animals | Pneumonia - drug therapy | Partial Thromboplastin Time | Anticoagulants - pharmacology | Mice | Neoplasms, Experimental - metabolism | Peritonitis - drug therapy | Carbohydrate Conformation | Pneumonia - metabolism | Neoplasms, Experimental - drug therapy
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10. Full Text Proximate composition and nutritional quality of deep sea growth sea cucumbers (Stichopus japonicus) from different origins
by Gao, Yue and Li, Zhibo and Qi, Yanxia and Guo, Zhenyu and Lin, Yantong and Li, Wei and Hu, Yucai and Zhao, Qiancheng
Journal of the Science of Food and Agriculture, ISSN 0022-5142, 05/2016, Volume 96, Issue 7, pp. 2378 - 2383
BACKGROUNDDeep sea growth sea cucumber (Stichopus japonicus) (DSG-SC) is considered a most nutritious and luxurious seafood in Asia. This study compared the... 
proximate composition | fatty acids | sea cucumber | nutritional quality | amino acids | Stichopus japonicus | Nutritional quality | Amino acids | Proximate composition | Sea cucumber | Fatty acids | FATTY-ACID-COMPOSITION | FOOD SCIENCE & TECHNOLOGY | FUCOSYLATED CHONDROITIN SULFATE | COLORIMETRIC METHOD | AMINO-ACID | IN-VITRO | PEPSIN-SOLUBILIZED COLLAGEN | CHEMICAL-COMPOSITION | POLYSACCHARIDES | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | APOSTICHOPUS-JAPONICUS | GLYCOSAMINOGLYCAN | Sea Cucumbers - chemistry | Food Analysis | Food Quality | Animals | Fatty Acids - chemistry | Nutritive Value | China | Amino Acids - chemistry | Polysaccharides - chemistry | Collagen - chemistry | Unsaturated fatty acids | Polysaccharides | Growth | Collagen | Seafood | Saturated fatty acids | Omega-3 fatty acids | Nutrition | Seafoods | Food quality | Proteins | Origins | Collagens | Cucumbers | Fucose
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11. Full Text Enzymatic preparation and structural determination of oligosaccharides derived from sea cucumber (Acaudina molpadioides) fucoidan
by Yu, Long and Xu, Xiaoqi and Xue, Changhu and Chang, Yaoguang and Ge, Lei and Wang, Yanchao and Zhang, Cuiyu and Liu, Guanchen and He, Chen
Food Chemistry, ISSN 0308-8146, 08/2013, Volume 139, Issue 1-4, pp. 702 - 709
► Sea cucumber fucoidan oligosaccharide was enzymatically prepared and analyzed. ► Oligosaccharide profile of enzymatic hydrolysate was determined by LC–MS. ►... 
Fucoidanase | Mass spectrum | Sea cucumber | Fucoidan | Oligosaccharide | LC–MS | LC-MS | DISACCHARIDES | SEQUENCE DETERMINATION | FOOD SCIENCE & TECHNOLOGY | COMPONENTS | FOODS | TANDEM MASS-SPECTROMETRY | IDENTIFICATION | HEPARIN | SULFATED FUCANS | ECHINODERMS | NUTRITION & DIETETICS | ANTICOAGULANT ACTIVITY | CHEMISTRY, APPLIED | Carbohydrate Sequence | Hydrolysis | Sea Cucumbers - chemistry | Tandem Mass Spectrometry | Animals | Magnetic Resonance Spectroscopy | Oligosaccharides - chemistry | Bacterial Proteins - chemistry | Molecular Sequence Data | Polysaccharides - chemistry | Flavobacteriaceae - enzymology | Food, Organic - analysis | Enzymes | Analysis
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12. Full Text Biological and taxonomic perspective of triterpenoid glycosides of sea cucumbers of the family Holothuriidae (Echinodermata, Holothuroidea)
by Honey-Escandón, Magali and Arreguín-Espinosa, Roberto and Solís-Marín, Francisco Alonso and Samyn, Yves
Comparative Biochemistry and Physiology, Part B, ISSN 1096-4959, 02/2015, Volume 180, pp. 16 - 39
Since the discovery of saponins in sea cucumbers, more than 150 triterpene glycosides have been described for the class Holothuroidea. The family Holothuriidae... 
Cuvierian tubules | Saponins | Taxonomy | family Holothuriidae | Family holothuriidae | Sea Cucumbers - chemistry | Triterpenes - chemistry | Animals | Saponins - classification | Glycosides - classification | Glycosides - chemistry | Saponins - chemistry | Triterpenes - classification | Sulfates
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13. Full Text Ultrasound effects on the degradation kinetics, structure, and antioxidant activity of sea cucumber fucoidan
by Guo, Xin and Ye, Xingqian and Sun, Yujing and Wu, Dan and Wu, Nian and Hu, Yaqin and Chen, Shiguo
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 02/2014, Volume 62, Issue 5, pp. 1088 - 1095
The effects of ultrasound on the molecular weight, structure, and antioxidant potential of a fucoidan found in Isostichopus badionotus were investigated. The... 
degradation | fucoidan | sea cucumber | ultrasound | AQUEOUS-SOLUTIONS | MOLECULAR-WEIGHT | FOOD SCIENCE & TECHNOLOGY | CHITOSAN | ANTICOAGULANT | CARRAGEENANS | PARAMETERS | SULFATED FUCANS | AGRICULTURE, MULTIDISCIPLINARY | HIGH-INTENSITY ULTRASOUND | CHEMISTRY, APPLIED | ANTITHROMBOTIC ACTIVITIES | POLYSACCHARIDE | Sea Cucumbers - chemistry | Animals | Antioxidants - chemistry | Polysaccharides - chemistry | Kinetics | Seafood - analysis | Ultrasonics
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14. Full Text Saponins from Sea Cucumber and Their Biological Activities
by Zhao, Ying-Cai and Xue, Chang-Hu and Zhang, Tian-Tian and Wang, Yu-Ming
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 07/2018, Volume 66, Issue 28, pp. 7222 - 7237
Sea cucumbers, belonging to the phylum Echinodermata, have been valued for centuries as a nutritious and functional food with various bioactivities. Sea... 
marine foods | mechanism | sea cucumber | bioactivities | saponins | IMMUNOMODULATORY PROPERTIES | PEARSONOTHURIA-GRAEFFEI | FOOD SCIENCE & TECHNOLOGY | ANTITUMOR ACTIVITIES | SULFATED TRITERPENE GLYCOSIDES | IN-VITRO | CUCUMARIA-OKHOTENSIS | ACID-ENRICHED PHOSPHOLIPIDS | INSULIN-RESISTANCE | AGRICULTURE, MULTIDISCIPLINARY | FATTY LIVER | CHEMISTRY, APPLIED | NF-KAPPA-B | Sea Cucumbers - chemistry | Animals | Saponins - isolation & purification | Humans | Sea Cucumbers - metabolism | Molecular Structure | Saponins - metabolism | Saponins - chemistry | Saponins - pharmacology | Index Medicus
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15. Full Text The formation pattern of off-flavor compounds induced by water migration during the storage of sea cucumber peptide powders (SCPPs)
by Wang, Ke and Yang, Ruiwen and Sun, Na and Dong, Yifei and Cheng, Sheng and Lin, Songyi
Food Chemistry, ISSN 0308-8146, 02/2019, Volume 274, pp. 100 - 109
The formation pattern of off-flavor compounds induced by water migration in sea cucumber peptide powders (SCPPs) stored at 25 °C and 75% RH for 24 h and... 
Off-flavor | Storage | Purge & trap-GC-MS | Water migration | Sea cucumber peptide | PINUS-KORAIENSIS PEPTIDE | ACID | COLLAGEN | QUALITY | PROTEIN | ANTIOXIDANT ACTIVITIES | FOOD SCIENCE & TECHNOLOGY | IDENTIFICATION | NUTRITION & DIETETICS | JAPONICUS | DIFFUSION | CHEMISTRY, APPLIED | CAKING | Pyrazines - analysis | Sea Cucumbers - chemistry | Microscopy, Electron, Scanning | Gas Chromatography-Mass Spectrometry | Magnetic Resonance Spectroscopy | Peptides - chemistry | Volatile Organic Compounds - analysis | Antioxidants - pharmacology | Spectroscopy, Fourier Transform Infrared | Food Storage - methods | Powders - chemistry | Animals | Aldehydes - analysis | Maillard Reaction | Phthalic Acids - analysis | Water - chemistry | Taste | Volatile Organic Compounds - chemistry | Antioxidants - analysis | Circular Dichroism | Peptides - analysis | Antioxidants | Peptides | Analysis
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