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1. Full Text Creatine biosynthesis and transport in health and disease
by Joncquel-Chevalier Curt, Marie and Voicu, Pia-Manuela and Fontaine, Monique and Dessein, Anne-Frédérique and Porchet, Nicole and Mention-Mulliez, Karine and Dobbelaere, Dries and Soto-Ares, Gustavo and Cheillan, David and Vamecq, Joseph
Biochimie, ISSN 0300-9084, 12/2015, Volume 119, pp. 146 - 165
GAMT | CRTR | SLC6A8 | AGAT | AMP activated protein kinase | Creatine | Secondary creatine disorders | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Transport Systems, Basic - genetics | Humans | Nerve Tissue Proteins - deficiency | Movement Disorders - diagnosis | Amidinotransferases - genetics | Intellectual Disability - metabolism | Biological Transport, Active | Gyrate Atrophy - enzymology | Amino Acid Metabolism, Inborn Errors - genetics | Intellectual Disability - enzymology | Brain Diseases, Metabolic, Inborn - genetics | Hyperammonemia - diagnosis | Hyperammonemia - genetics | Creatine - genetics | Urea Cycle Disorders, Inborn - metabolism | Creatine - biosynthesis | Gyrate Atrophy - genetics | Plasma Membrane Neurotransmitter Transport Proteins - metabolism | Guanidinoacetate N-Methyltransferase - metabolism | Amidinotransferases - metabolism | Plasma Membrane Neurotransmitter Transport Proteins - genetics | Language Development Disorders - enzymology | Urea Cycle Disorders, Inborn - diagnosis | Energy Metabolism | Urea Cycle Disorders, Inborn - enzymology | Movement Disorders - genetics | Mutation | Ornithine - deficiency | Amino Acid Transport Systems, Basic - metabolism | Amino Acid Metabolism, Inborn Errors - enzymology | S-Adenosylmethionine - metabolism | AMP-Activated Protein Kinases - metabolism | Hyperammonemia - metabolism | Developmental Disabilities - metabolism | Guanidinoacetate N-Methyltransferase - genetics | Ornithine - genetics | Developmental Disabilities - genetics | Language Development Disorders - metabolism | Brain Diseases, Metabolic, Inborn - enzymology | Brain Diseases, Metabolic, Inborn - diagnosis | Intellectual Disability - genetics | Amino Acid Metabolism, Inborn Errors - diagnosis | Amino Acid Metabolism, Inborn Errors - metabolism | Mental Retardation, X-Linked - genetics | Mental Retardation, X-Linked - enzymology | Developmental Disabilities - enzymology | Language Development Disorders - diagnosis | Mental Retardation, X-Linked - diagnosis | Movement Disorders - enzymology | Creatine - metabolism | Hyperammonemia - enzymology | Creatine - deficiency | Gyrate Atrophy - diagnosis | Developmental Disabilities - diagnosis | Speech Disorders - diagnosis | Plasma Membrane Neurotransmitter Transport Proteins - deficiency | Speech Disorders - metabolism | Amidinotransferases - deficiency | Brain Diseases, Metabolic, Inborn - metabolism | Language Development Disorders - genetics | Ornithine - metabolism | Gyrate Atrophy - metabolism | Prenatal Diagnosis | Speech Disorders - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Amino Acid Transport Systems, Basic - deficiency | Movement Disorders - metabolism | Animals | Urea Cycle Disorders, Inborn - genetics | Guanidinoacetate N-Methyltransferase - deficiency | Intellectual Disability - diagnosis | Movement Disorders - congenital | Speech Disorders - enzymology | Methylation | Mental Retardation, X-Linked - metabolism | Antioxidants | Phosphates | Algorithms | Animal behavior | Physiological aspects | GABA | Glycine | Phosphotransferases | Medical research | Medicine, Experimental | Protein kinases | Index Medicus | Life Sciences
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2. Full Text Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis
by Raymond W. Bourdeau and Enrico Malito and Alexandre Chenal and Brian L. Bishop and Mark W. Musch and Mitch L. Villereal and Eugene B. Chang and Elise M. Mosser and Richard F. Rest and Wei-Jen Tang and Argonne National Lab. (ANL), Argonne, IL (United States)
The Journal of biological chemistry, ISSN 0021-9258, 05/2009, Volume 284, Issue 21, pp. 14645 - 14656
Solubility - drug effects | Epithelial Cells - metabolism | Membrane Glycoproteins - metabolism | Calcium - metabolism | Bacteriocins - chemistry | Epithelial Cells - drug effects | Humans | Membrane Glycoproteins - chemistry | Protein Multimerization | Bacterial Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | Hemolysin Proteins - chemistry | Occludin | Protein Binding - drug effects | Protein Structure, Quaternary | Membrane Proteins - metabolism | Bacteriocins - metabolism | Epithelial Cells - cytology | Bacillus anthracis - metabolism | Tight Junctions - drug effects | Caco-2 Cells | Protein Structure, Tertiary | Tight Junctions - metabolism | Amino Acid Sequence | Permeability - drug effects | Intracellular Space - drug effects | Protein Structure, Secondary | Perforin - chemistry | Models, Molecular | Bacillus anthracis - cytology | Cholesterol - metabolism | Bacterial Toxins - chemistry | Bacterial Toxins - metabolism | Intracellular Space - metabolism | Ionomycin - pharmacology | Bacterial Proteins - metabolism | Perforin - metabolism | Hemolysin Proteins - metabolism | Intestines - cytology | Index Medicus | Life Sciences | Biochemistry, Molecular Biology | HUMAN POPULATIONS | PATHOGENESIS | ELEMENTS | CALCIUM | LIGHT SCATTERING | CRYSTAL STRUCTURE | DIMERIZATION | MATERIALS SCIENCE | BACILLUS | FUNCTIONS | PROTEINS | ULTRACENTRIFUGATION
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3. Full Text Excess TGF-β mediates muscle weakness associated with bone metastases in mice
by Waning, David L and Mohammad, Khalid S and Reiken, Steven and Xie, Wenjun and Andersson, Daniel C and John, Sutha and Chiechi, Antonella and Wright, Laura E and Umanskaya, Alisa and Niewolna, Maria and Trivedi, Trupti and Charkhzarrin, Sahba and Khatiwada, Pooja and Wronska, Anetta and Haynes, Ashley and Benassi, Maria Serena and Witzmann, Frank A and Zhen, Gehua and Wang, Xiao and Cao, Xu and Roodman, G. David and Marks, Andrew R and Guise, Theresa A
Nature medicine, ISSN 1078-8956, 11/2015, Volume 21, Issue 11, pp. 1262 - 1271
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Neoplasms - metabolism | Prostatic Neoplasms - metabolism | Up-Regulation | Calcium - metabolism | Humans | Lung Neoplasms - metabolism | NADPH Oxidases - metabolism | Bone Neoplasms - secondary | Lung Neoplasms - pathology | Male | Muscle, Skeletal - metabolism | Osteolysis - etiology | Ryanodine Receptor Calcium Release Channel - metabolism | X-Ray Microtomography | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Neoplasms - complications | MCF-7 Cells | Osteolysis - diagnostic imaging | Muscle Proteins - metabolism | NADPH Oxidases - genetics | Female | Camurati-Engelmann Syndrome - metabolism | Muscle Strength | Calcium Signaling | Disease Models, Animal | Muscle Weakness - etiology | Prostatic Neoplasms - pathology | Oxidation-Reduction | Bone Neoplasms - diagnostic imaging | NADPH Oxidase 4 | Mice, SCID | Multiple Myeloma - metabolism | Absorptiometry, Photon | Osteolysis - metabolism | Multiple Myeloma - pathology | Animals | Muscle Contraction | Breast Neoplasms - pathology | Mice, Nude | Muscle Weakness - metabolism | Cell Line, Tumor | Mice | Neoplasms - pathology | Transforming Growth Factor beta - metabolism | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1
by Zhuang, Xueqian and Zhang, Hao and Li, Xiaoyan and Li, Xiaoxun and Cong, Min and Peng, Fangli and Yu, Jingyi and Zhang, Xue and Yang, Qifeng and Hu, Guohong
Nature cell biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 10, pp. 1274 - 1285
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Lung Neoplasms - metabolism | Transforming Growth Factor beta1 - metabolism | Bone Neoplasms - secondary | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Molecular Targeted Therapy | Neutrophil Infiltration | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Transfection | Lung Neoplasms - secondary | RNA Interference | Time Factors | Female | Antineoplastic Agents - pharmacology | Bone Neoplasms - genetics | Neuropeptides - genetics | Neutrophils - metabolism | Calcium Signaling | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Latent TGF-beta Binding Proteins - metabolism | Neutrophils - pathology | Lung Neoplasms - genetics | Macrophages - pathology | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Neuropeptides - metabolism | Mice, SCID | Breast Neoplasms - drug therapy | Cell Movement - drug effects | Osteoblasts - pathology | Macrophages - metabolism | Animals | Breast Neoplasms - genetics | Wnt Signaling Pathway - drug effects | Lung Neoplasms - prevention & control | Bone Neoplasms - prevention & control | Breast Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Mice, Inbred NOD | Mice, Inbred BALB C | HeLa Cells | Osteoblasts - metabolism | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Care and treatment | Bone morphogenetic proteins | Breast cancer | Metastasis | Transforming growth factors | Health aspects | Cancer | Wnt protein | Secretion | Lung cancer | Organs | Rac1 protein | JNK protein | Macrophages | Osteoblasts | Metastases | Recruitment | Calcium signalling | Biomedical materials | Bone cancer | Lungs | Biocompatibility | Dkk1 protein | Organotropism | Tumors | Ca2+/calmodulin-dependent protein kinase II | Index Medicus
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5. Full Text UpaG, a New Member of the Trimeric Autotransporter Family of Adhesins in Uropathogenic Escherichia coli
by Jaione Valle and Amanda N. Mabbett and Glen C. Ulett and Alejandro Toledo-Arana and Karine Wecker and Makrina Totsika and Mark A. Schembri and Jean-Marc Ghigo and Christophe Beloin
Journal of Bacteriology, ISSN 0021-9193, 06/2008, Volume 190, Issue 12, pp. 4147 - 4161
Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Bacteriology | Epithelial Cells - metabolism | Humans | Biofilms - growth & development | Molecular Sequence Data | Adhesins, Escherichia coli - chemistry | Adhesins, Escherichia coli - genetics | Bacterial Adhesion - physiology | Escherichia coli - metabolism | Female | Escherichia coli - growth & development | Dimerization | Urinary Tract - microbiology | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Adhesins, Escherichia coli - metabolism | Protein Structure, Secondary | Escherichia coli Infections - microbiology | Escherichia coli Proteins - metabolism | Escherichia coli Infections - metabolism | Blotting, Western | Fibronectins - metabolism | Sequence Homology, Amino Acid | Animals | Escherichia coli - genetics | Epithelial Cells - microbiology | Bacterial Adhesion - genetics | Escherichia coli Proteins - genetics | Mice | HeLa Cells | Laminin - metabolism | Escherichia coli Proteins - chemistry | Microscopy, Fluorescence | Usage | Carrier proteins | Escherichia coli | Physiological aspects | Genetic aspects | Research | Gene expression | Proteins | Eukaryotes | Biochemistry | E coli | Molecular biology | Index Medicus | Biofilms/growth & development | Adhesins, Escherichia coli/chemistry | Life Sciences | Adhesins, Escherichia coli/genetics | Escherichia coli Proteins/genetics | Escherichia coli/growth & development | Laminin/metabolism | Epithelial Cells/metabolism | Adhesins, Escherichia coli/metabolism | Escherichia coli Infections/metabolism | Escherichia coli/genetics | Escherichia coli/metabolism | Microbiology and Parasitology | Epithelial Cells/microbiology | Escherichia coli Proteins/chemistry | Escherichia coli Proteins/metabolism | Fibronectins/metabolism | Escherichia coli Infections/microbiology | Urinary Tract/microbiology | Bacterial Adhesion/genetics | Bacterial Adhesion/physiology | Molecular Biology of Pathogens
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6. Full Text Breast cancer osteomimicry and its role in bone specific metastasis; an integrative, systematic review of preclinical evidence
by Awolaran, Olugbenga and Brooks, Susan A and Lavender, Verna
Breast (Edinburgh), ISSN 0960-9776, 2016, Volume 30, pp. 156 - 171
Hematology, Oncology and Palliative Medicine | Breast cancer | Metastasis | Bone | Osteomimicry | Oncology | Life Sciences & Biomedicine | Obstetrics & Gynecology | Science & Technology | Cadherins - metabolism | Membrane Glycoproteins - metabolism | Humans | Bone Neoplasms - secondary | Osteopontin - metabolism | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Neoplasm Metastasis | Chemokine CCL2 - metabolism | Repressor Proteins - metabolism | Phosphoric Diester Hydrolases - metabolism | Receptors, Chemokine - metabolism | Interleukin-11 - metabolism | Adrenomedullin - metabolism | Nephroblastoma Overexpressed Protein - metabolism | Receptors, CXCR4 - metabolism | Pyrophosphatases - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Animals | Breast Neoplasms - pathology | Cell Line, Tumor | Trans-Activators - metabolism | Twist-Related Protein 1 - metabolism | CX3C Chemokine Receptor 1 | Integrin-Binding Sialoprotein - metabolism | Connective Tissue Growth Factor - metabolism | Proteins | Development and progression | Index Medicus
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