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Biochimica et biophysica acta. Biomembranes, ISSN 0005-2736, 2013, Volume 1828, Issue 12, pp. 2898 - 2907
Journal Article
The EMBO journal, ISSN 1460-2075, 2019, Volume 38, Issue 12, p. n/a
γ‐Secretase complexes (GSECs) are multimeric membrane proteases involved in a variety of physiological processes and linked to Alzheimer's disease (AD).... 
γ‐secretase | γ‐secretase modulators | Nicastrin | Alzheimer's disease | amyloid‐beta | amyloid-beta | γ-secretase modulators | γ-secretase | APH-1 | SPECIFICITY | PRESENILIN GENERATE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | gamma-secretase | NOTCH | TRANSMEMBRANE DOMAIN | AMYLOID PRECURSOR PROTEIN | CLEAVAGE | CELL BIOLOGY | gamma-secretase modulators | MUTATIONS | MOLECULAR-DYNAMICS SIMULATIONS | Membrane Glycoproteins - metabolism | Protein Interaction Domains and Motifs - physiology | Amyloid beta-Protein Precursor - chemistry | Humans | Membrane Glycoproteins - chemistry | Cells, Cultured | Models, Molecular | Structure-Activity Relationship | Extracellular Space | Amyloid Precursor Protein Secretases - chemistry | Amyloid Precursor Protein Secretases - metabolism | Animals | Proteolysis | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Protein Structure, Quaternary | Protein Binding | Mice | Molecular Docking Simulation | Amyloid beta-Peptides - chemistry | Enzyme Activation | Amyloidogenesis | PEN-2 protein | Peptides | Neurodegenerative diseases | Pathogenesis | Nucleotides | Pharynx | Neuromodulation | Modulators | Amyloid precursor protein | Substrates | Neurotoxicity | Interface stability | Presenilin 2 | Mutation | Catalysis | Drug discovery | Alzheimers disease | Secretase | Index Medicus | Neuroscience | Post-translational Modifications, Proteolysis & Proteomics | Molecular Biology of Disease
Journal Article