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Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 6, pp. 1008 - 1015
The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked... 
PULMONARY-HYPERTENSION | PERMEABILITY | 5-HYDROXYTRYPTAMINE | ENDOTHELIAL-CELLS | MAST-CELLS | P-SELECTIN | RECEPTOR | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | VON-WILLEBRAND-FACTOR | SELECTIN-DEFICIENT MICE | Blood Platelets - immunology | Endothelium, Vascular - drug effects | Male | Shock, Septic - immunology | Lipopolysaccharides | Serotonin - blood | Inflammation - metabolism | L-Selectin - immunology | Leukocytosis - metabolism | Weibel-Palade Bodies - metabolism | Chemotaxis - immunology | Neutrophils - metabolism | Serotonin - immunology | Serotonin Uptake Inhibitors - immunology | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Fluoxetine - pharmacology | Acute Disease | Neutrophils - drug effects | Leukocytosis - immunology | Chemotaxis - drug effects | Mice, Knockout | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Mice | Serotonin Uptake Inhibitors - pharmacology | Leukocyte Rolling - drug effects | Weibel-Palade Bodies - immunology | Histamine - immunology | L-Selectin - metabolism | Flow Cytometry | Tryptophan Hydroxylase - deficiency | Blood Platelets - drug effects | Fluoxetine - immunology | Shock, Septic - genetics | Leukocyte Rolling - genetics | Histamine - pharmacology | Shock, Septic - chemically induced | Mice, Inbred C57BL | Kaplan-Meier Estimate | Neutrophils - immunology | Inflammation - immunology | Leukocyte Rolling - immunology | Tryptophan Hydroxylase - genetics | Weibel-Palade Bodies - drug effects | Animals | Serotonin - metabolism | Inflammation - genetics | Leukocytosis - genetics | Phagocytes, Granulocytes, and Myelopoiesis | Platelets and Thrombopoiesis
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 06/2013, Volume 210, Issue 6, pp. 1189 - 1200
The forkhead O transcription factors (FOXO) integrate a range of extracellular signals, including growth factor signaling, inflammation, oxidative stress, and... 
TRANSCRIPTION FACTORS | EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | L-SELECTIN | IN-VIVO | INFECTION | IMMUNOLOGY | BETA-CATENIN | NAIVE | EXPRESSION | CUTTING EDGE | Forkhead Transcription Factors - immunology | Lymphocytic choriomeningitis virus - immunology | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - cytology | Granzymes - metabolism | Lectins, C-Type - immunology | Cell Survival - genetics | T-Box Domain Proteins - immunology | Granzymes - genetics | Lectins, C-Type - genetics | Lymphocytic Choriomeningitis - immunology | Antigens, CD - genetics | Antigens, CD - metabolism | Cell Differentiation - genetics | Lectins, C-Type - metabolism | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Forkhead Transcription Factors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Granzymes - immunology | T Cell Transcription Factor 1 - metabolism | Immunologic Memory - genetics | Immunologic Memory - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Hepatocyte Nuclear Factor 1-alpha | Antigens, Differentiation, T-Lymphocyte - metabolism | Mice, Transgenic | Cell Survival - immunology | Forkhead Transcription Factors - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | T Cell Transcription Factor 1 - genetics | Cell Differentiation - immunology | Animals | Up-Regulation - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | T Cell Transcription Factor 1 - immunology | Forkhead Box Protein O1 | Mice | CD8-Positive T-Lymphocytes - immunology | 309
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87131
The possibility to modulate ex vivo human NK cell differentiation towards specific phenotypes will contribute to a better understanding of NK cell... 
NATURAL-KILLER-CELLS | L-SELECTIN | DISPLAY | MANNOSE RECEPTOR | IMMUNOTHERAPY | CD56(BRIGHT) | MULTIDISCIPLINARY SCIENCES | BIOLOGY | GENE-EXPRESSION | TRANSCRIPTION FACTOR | CYTOTOXICITY | Receptors, CCR6 - immunology | Humans | Neoplasm Proteins - immunology | Antibody-Dependent Cell Cytotoxicity - immunology | Inhibitor of Differentiation Proteins - genetics | Receptors, IgG - metabolism | L-Selectin - immunology | Antigens, CD34 - immunology | Receptors, KIR - metabolism | Neoplasm Proteins - genetics | Fetal Blood - immunology | Immunotherapy, Adoptive - methods | Receptors, CXCR3 - metabolism | Antineoplastic Agents - immunology | Rituximab | Fetal Blood - cytology | Receptors, IgG - immunology | Reverse Transcriptase Polymerase Chain Reaction | Cell Differentiation - immunology | Inhibitor of Differentiation Proteins - immunology | K562 Cells | Receptors, CXCR3 - immunology | Cell Line, Tumor | Interleukin-2 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Antibodies, Monoclonal, Murine-Derived - pharmacology | Receptors, KIR - immunology | GATA3 Transcription Factor - genetics | Antigens, CD34 - metabolism | GATA3 Transcription Factor - immunology | L-Selectin - metabolism | Dose-Response Relationship, Drug | High Mobility Group Proteins - immunology | Cell Differentiation - genetics | Hematopoietic Stem Cells - immunology | Flow Cytometry | Interleukin-2 - immunology | Receptors, CCR6 - metabolism | Killer Cells, Natural - immunology | Antineoplastic Agents - pharmacology | Hematopoietic Stem Cells - drug effects | Antibodies, Monoclonal, Murine-Derived - immunology | Cells, Cultured | Hematopoietic Stem Cells - metabolism | Fetal Blood - metabolism | Cell Differentiation - drug effects | Antibody-Dependent Cell Cytotoxicity - drug effects | High Mobility Group Proteins - genetics | Fc receptors | Killer cells | Immunotherapy | Leukemia | Stem cells | Cell differentiation | Health aspects | Cytolytic activity | Lymphocyte receptors | Transcription factors | Toxicity | Differentiation (biology) | Cytotoxicity | Biology | Blood | NKG2 antigen | Receptors | Cord blood | Peripheral blood | Killer cell immunoglobulin-like receptors | Physiology | Natural killer cells | CD34 antigen | Cytokines | Maturation | Gynecology | CD62L protein | Interleukin 12 | T cell receptors | Pharmacology | CXCR3 protein | Gene expression | Obstetrics | Thrombosis | CCR6 protein | CD16 antigen | Major histocompatibility complex | Lymphocytes B | GATA-3 protein | Ligands | Umbilical cord | Chemokines | Cancer
Journal Article
Journal Article
Trends in Immunology, ISSN 1471-4906, 2011, Volume 32, Issue 10, pp. 486 - 492
Natural killer (NK) cells are highly motile cells that patrol lymphoid and non-lymphoid organs, and are poised to react to infectious or other inflammatory... 
Allergy and Immunology | L-SELECTIN | MURINE CYTOMEGALOVIRUS-INFECTION | ROR-GAMMA-T | DENDRITIC CELLS | IFN-GAMMA | LYMPH-NODES | IN-VIVO | CHEMOKINE RECEPTOR | HUMAN NK CELLS | IMMUNOLOGY | CD8(+) T-CELLS | Neoplasms - metabolism | Cell Communication - immunology | Inflammation - pathology | Lysophospholipids - metabolism | Receptors, G-Protein-Coupled - metabolism | Dendritic Cells - immunology | Humans | Lysophospholipids - immunology | Receptors, G-Protein-Coupled - immunology | Cell Movement - immunology | Signal Transduction - immunology | Inflammation - metabolism | Liver - immunology | Bone Marrow Cells - immunology | Killer Cells, Natural - immunology | Sphingosine - metabolism | Dendritic Cells - metabolism | Chemokines - immunology | Liver - metabolism | Receptors, Chemokine - metabolism | Lymph Nodes - metabolism | Sphingosine - immunology | Inflammation - immunology | Lymph Nodes - immunology | Receptors, Chemokine - immunology | Immunity, Innate | Lymph Nodes - cytology | Sphingosine - analogs & derivatives | Animals | Neoplasms - immunology | Chemokines - metabolism | Liver - cytology | Mice | Killer Cells, Natural - metabolism | Neoplasms - pathology | Bone Marrow Cells - metabolism | Cytotoxicity, Immunologic | Phosphates | Killer cells | Sphingosine | Studies | Spleen | Antigens | Aqueous solutions | Cytotoxicity | Ligands | Infections | Chemokines | Immune system | Cancer | Life Sciences | Immunology
Journal Article
Journal Article
Journal Article