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Endocrine-Related Cancer, ISSN 1351-0088, 03/2010, Volume 17, Issue 1, pp. 17 - 25
Journal Article
European Urology, ISSN 0302-2838, 2015, Volume 68, Issue 1, pp. 77 - 83
Journal Article
Fertility and Sterility, ISSN 0015-0282, 2015, Volume 103, Issue 5, pp. 1297 - 1304
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2012, Volume 7, Issue 7, pp. e40858 - e40858
Patients with Disorders of Sex Development (DSD), especially those with gonadal dysgenesis and hypovirilization are at risk of developing malignant type II... 
NUCLEAR IMPORT | TESTICULAR DYSGENESIS SYNDROME | MALE SEXUAL DEVELOPMENT | BIOLOGY | GERM-CELL TUMORS | DISORDERS | SOX9 | DIFFERENTIATION | FRASIER-SYNDROME | MOSAIC FATHER | EXPRESSION | Immunohistochemistry | Sex-Determining Region Y Protein - genetics | Amino Acid Sequence | RNA Splice Sites - genetics | Humans | Gonadal Dysgenesis, 46,XY - pathology | Molecular Sequence Data | Mutation, Missense - genetics | Frasier Syndrome - genetics | Ovarian Neoplasms - genetics | Young Adult | WT1 Proteins - chemistry | Gonadoblastoma - genetics | DNA Mutational Analysis | Base Sequence | Gonadal Dysgenesis, 46,XY - genetics | Gonadoblastoma - pathology | Female | WT1 Proteins - genetics | Women | Embryonic development | Chromosomal proteins | Chronic kidney failure | Analysis | Germ cell tumors | Development and progression | Genetic aspects | Health aspects | Pediatrics | Transformation | Germ cells | Sox9 protein | Risk | Sclerosis | Embryogenesis | Missense mutation | Uterus | Failure analysis | Amenorrhea | Genetics | Diagnosis | Deoxyribonucleic acid--DNA | Medical research | Frasier syndrome | Genetic disorders | Streak | Invasiveness | Laparoscopy | Ovaries | Patients | Hypogonadism | Nuclear transport | Gonadal dysgenesis | Pathology | Seminoma | Renal failure | Mutation | Females | Endocrinology | Tumors | Kidney transplantation | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, pp. e43952 - e43952
textabstractActivating c-KIT mutations (exons 11 and 17) are found in 10-40% of testicular seminomas, the majority being missense point mutations (codon 816).... 
Y-CHROMOSOME | GENE | MULTIDISCIPLINARY SCIENCES | TESTICULAR SEMINOMA | GERM-CELL TUMORS | RECEPTOR | GASTROINTESTINAL STROMAL TUMORS | EXPRESSION | GENOME-WIDE ASSOCIATION | INTERSTITIAL-CELLS | FEMALE | Humans | Ovarian Neoplasms - pathology | Child, Preschool | Infant | Male | Dysgerminoma - complications | Ovarian Neoplasms - complications | Proto-Oncogene Proteins c-kit - metabolism | Testicular Neoplasms - pathology | Testicular Neoplasms - complications | Octamer Transcription Factor-3 - genetics | Ovarian Neoplasms - genetics | DNA Mutational Analysis | Disorders of Sex Development - pathology | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Disorders of Sex Development - complications | Adult | Female | Proto-Oncogene Proteins c-kit - genetics | Child | Dysgerminoma - pathology | Testicular Neoplasms - genetics | Gonadoblastoma - complications | Cell Cycle Proteins - metabolism | Dysgerminoma - genetics | Disorders of Sex Development - genetics | Gonadoblastoma - genetics | Octamer Transcription Factor-3 - metabolism | Adolescent | Gonadoblastoma - pathology | Biomarkers, Tumor - genetics | Mutation | Gene mutations | Germ cell tumors | Physiological aspects | Genetic aspects | Research | Risk factors | Prevalence studies (Epidemiology) | Sequences | Exons | Oct-4 protein | Health risks | Melting curve | Kinases | c-Kit protein | Patients | Aberration | Lesions | Testes | Chromosomes | Chromosome aberrations | Cancer | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2007, Volume 120, Issue 7, pp. 1598 - 1602
Journal Article
Genes and Development, ISSN 0890-9369, 2012, Volume 26, Issue 8, pp. 797 - 802
Journal Article
Reproduction, ISSN 1470-1626, 2017, Volume 154, Issue 4, pp. 363 - 374
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e82881 - e82881
During mammalian development the fertilized zygote and primordial germ cells lose their DNA methylation within one cell cycle leading to the concept of active... 
CARCINOMA-IN-SITU | STEM-CELLS | METHYLATION | MAMMALIAN DNA | MULTIDISCIPLINARY SCIENCES | LINE | 5-HYDROXYMETHYLCYTOSINE | MOUSE PREIMPLANTATION DEVELOPMENT | ACTIVE DNA DEMETHYLATION | DIFFERENTIATION | TUMORS | Immunohistochemistry | Proto-Oncogene Proteins - metabolism | Cytosine - analogs & derivatives | Testis - metabolism | Oxidation-Reduction | Spermatogenesis | Down-Regulation | Humans | Male | Neoplasms, Germ Cell and Embryonal - metabolism | Proto-Oncogene Proteins - genetics | Neoplasms, Germ Cell and Embryonal - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | DNA Methylation | 5-Methylcytosine - metabolism | Cytosine - metabolism | Testis - enzymology | Proto-Oncogene Proteins - physiology | Cell Line, Tumor | Carcinoma - genetics | Carcinoma - metabolism | Germ Cells - metabolism | Oxidation-reduction reaction | Pyrimidines | Methyltransferases | Methylation | Gene expression | Genes | Biotechnology | Germ cells | Neuropathology | Sperm | DNA damage | DNA glycosylase | Genomes | Tissues | Base excision repair | Demethylation | Cell cycle | Xenografts | DNA methylation | Oxidation | Cytosine | Deoxyribonucleic acid--DNA | Tumor cell lines | Pathology | Seminoma | Correlation analysis | Cell lines | Epigenetics | Mutation | Cancer | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article