X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (867) 867
Publication (91) 91
Book Chapter (23) 23
Dissertation (8) 8
Book Review (5) 5
Conference Proceeding (4) 4
Book / eBook (1) 1
Government Document (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
semisynthesis (770) 770
index medicus (325) 325
biochemistry & molecular biology (274) 274
chemistry, organic (196) 196
chemistry, multidisciplinary (171) 171
humans (167) 167
animals (160) 160
chemistry, medicinal (155) 155
proteins (118) 118
derivatives (106) 106
molecular structure (101) 101
structure-activity relationship (97) 97
amino acid sequence (93) 93
ligation (78) 78
chemistry (76) 76
molecular sequence data (73) 73
protein semisynthesis (73) 73
models, molecular (69) 69
native chemical ligation (69) 69
peptides (68) 68
article (66) 66
analogs (64) 64
synthesis (54) 54
protein (53) 53
analysis (51) 51
catalysis (51) 51
esters (51) 51
protein conformation (50) 50
protein engineering (50) 50
cancer (48) 48
peptides - chemistry (48) 48
cell line, tumor (45) 45
natural-products (45) 45
research (45) 45
cytotoxicity (44) 44
kinetics (43) 43
insecticidal activity (42) 42
natural products (42) 42
pharmacology & pharmacy (42) 42
phosphorylation (42) 42
antineoplastic agents - pharmacology (41) 41
biosynthesis (40) 40
binding (39) 39
inteins (39) 39
organic chemistry (39) 39
agents (37) 37
protein splicing (37) 37
antineoplastic agents - chemical synthesis (36) 36
biophysics (36) 36
escherichia-coli (35) 35
mice (35) 35
antineoplastic agents - chemistry (34) 34
cysteine (34) 34
peptides - chemical synthesis (34) 34
amino acids (33) 33
chromatography, high pressure liquid (33) 33
enzymes (33) 33
peptide (33) 33
activation (32) 32
crystal-structure (32) 32
expressed protein ligation (32) 32
stereoisomerism (32) 32
in-vitro (31) 31
mechanism (31) 31
podophyllotoxin (31) 31
proteins - chemistry (31) 31
chemical-synthesis (30) 30
binding sites (29) 29
chemical synthesis (29) 29
cells (28) 28
intein (28) 28
peptide fragments - chemistry (28) 28
chemistry, applied (27) 27
drug screening assays, antitumor (27) 27
protein engineering - methods (27) 27
taxol (27) 27
biochemical research methods (26) 26
biological evaluation (26) 26
inhibitors (26) 26
oxidation (26) 26
solid-phase synthesis (26) 26
ligands (25) 25
mass spectrometry (25) 25
multidisciplinary sciences (25) 25
protein folding (25) 25
crystallography, x-ray (24) 24
cytochrome c (24) 24
design (24) 24
diterpenes - chemistry (24) 24
paclitaxel (24) 24
protein binding (24) 24
protein processing, post-translational (24) 24
apoptosis (23) 23
biotechnology & applied microbiology (23) 23
cell proliferation - drug effects (23) 23
chemical ligation (23) 23
chemical properties (23) 23
hydrogen-ion concentration (23) 23
in-vivo (23) 23
magnetic resonance spectroscopy (23) 23
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


ChemBioChem, ISSN 1439-4227, 01/2019, Volume 20, Issue 1, pp. 4 - 4
The cover feature picture shows a modular connector approach for presenting semisynthetic cyclic peptides on the cell surface of E. coli. Cyclization is... 
semisynthesis | bacterial display | oxime ligation | macrocycles | inteins
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 05/2017, Volume 56, Issue 19, p. n/a
Huntington's Disease In their Communication on page 5202 ff. H. A. Lashuel et al. use protein semisynthesis to investigate the effect of lysine acetylation and... 
acetylation | semisynthesis | Huntington's disease | phosphorylation | fibrils | Phosphorylation
Journal Article
ChemBioChem, ISSN 1439-4227, 01/2020, Volume 21, Issue 1-2, pp. 64 - 68
The activity and localization of PTEN, a tumor suppressor lipid phosphatase that converts the phospholipid PIP3 to PIP2, is governed in part by phosphorylation... 
semisynthesis | PTEN | phosphorylation | enzyme kinetics | phosphatases
Journal Article
Dyes and Pigments, ISSN 0143-7208, 04/2020, Volume 175, p. 108155
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2019, Volume 58, Issue 6, pp. 1616 - 1620
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 09/2018, Volume 38, Issue 9, pp. 2348 - 2362
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 05/2019, Volume 55, Issue 49, pp. 7029 - 7032
A traceless thioester-producing protocol featuring carboxypeptidase Y-mediated hydrazinolysis of cysteinyl prolyl leucine-tagged peptides has been developed.... 
Journal Article
Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 49, pp. 7029 - 7032
A traceless thioester-producing protocol featuring carboxypeptidase Y-mediated hydrazinolysis of cysteinyl prolyl leucine-tagged peptides has been developed.... 
CARBOXYPEPTIDASE-Y | SEMISYNTHESIS | ACTIVATION | NATIVE CHEMICAL LIGATION | ALPHA-THIOESTER | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 12/2019, Volume 188, p. 112005
To address the global challenge of emerging antimicrobial resistance, the hitherto most successful strategy to new antibiotics has been the optimization of... 
Journal Article
Nature Protocols, ISSN 1754-2189, 2013, Volume 8, Issue 12, pp. 2483 - 2495
Journal Article
by Ma, SJ and Yu, J and Yan, DW and Wang, DC and Gao, JM and Zhang, Q
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 12/2018, Volume 16, Issue 48, pp. 9454 - 9460
Meroterpenoids isolated from guava (Psidium guajava) and Rhodomyrtus tomentosa possess special skeletons which incorporate terpenoids with phloroglucinol... 
BIOMIMETIC TOTAL-SYNTHESIS | SEMISYNTHESIS | NATURAL-PRODUCTS | DRIVEN DIVERSITY | LEAVES | LIBRARY | CHEMISTRY, ORGANIC | UNUSUAL SKELETONS | PSIGUADIALS | DISCOVERY
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2019, Volume 17, Issue 17, pp. 4261 - 4272
Bioinspired sulfa-Michael/aldol cascade reactions have been developed for the semisynthesis of sulfur-containing heterocyclic derivatives of platensimycin and... 
Stereoselectivity | Semisynthesis | Nuclear magnetic resonance--NMR | Density functional theory | Stereochemistry | Cascade chemical reactions | Aldehydes | Sulfur
Journal Article