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Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 2, pp. 153 - 163
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 770 - 778
Summary Background Pancreatic cancer statistics are dismal, with a 5-year survival of less than 10%, and more than 50% of patients presenting with metastatic... 
Hematology, Oncology and Palliative Medicine | ONCOLOGY | MITOCHONDRIAL METABOLISM | Leucovorin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Sulfides - administration & dosage | Pancreatic Neoplasms - drug therapy | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Hyperglycemia - chemically induced | Leucovorin - adverse effects | Fluorouracil - adverse effects | Hypokalemia - chemically induced | Camptothecin - administration & dosage | Female | Neutropenia - chemically induced | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Hematologic Diseases - chemically induced | Sensation Disorders - chemically induced | Abdominal Pain - chemically induced | Pancreatic Neoplasms - pathology | Anemia - chemically induced | Thrombocytopenia - chemically induced | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Hypoalbuminemia - chemically induced | Maximum Tolerated Dose | Sepsis - chemically induced | Sulfides - adverse effects | Aged | Caprylates - administration & dosage | Caprylates - adverse effects | Organoplatinum Compounds - adverse effects | Lymphopenia - chemically induced | Enzymes | Medical colleges | Care and treatment | Metastasis | Antineoplastic agents | Cells | Antimitotic agents | Cancer patients | Chemotherapy | Pancreatic cancer | Physiological aspects | Product development | Cancer
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 792 - 802
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 6, pp. 732 - 742
Summary Background The antibody–drug conjugate trastuzumab emtansine is indicated for the treatment of patients with HER2-positive metastatic breast cancer... 
Hematology, Oncology and Palliative Medicine | RECEPTOR | ONCOLOGY | PERTUZUMAB | DOCETAXEL | GUIDELINES | Capecitabine - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Response Evaluation Criteria in Solid Tumors | Antineoplastic Agents - therapeutic use | Hand-Foot Syndrome - etiology | Diarrhea - chemically induced | Young Adult | Breast Neoplasms - chemistry | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Quinazolines - administration & dosage | Lapatinib | Antibodies, Monoclonal, Humanized - adverse effects | Maytansine - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Maytansine - analogs & derivatives | Anemia - chemically induced | Survival Rate | Thrombocytopenia - chemically induced | Trastuzumab - administration & dosage | Breast Neoplasms, Male - drug therapy | Maytansine - therapeutic use | Breast Neoplasms - drug therapy | Breast Neoplasms, Male - chemistry | Disease-Free Survival | Retreatment | Taxoids - administration & dosage | Vomiting - chemically induced | Aspartate Aminotransferases - blood | Capecitabine - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Quinazolines - adverse effects | Aged | Breast Neoplasms, Male - pathology | Receptor, ErbB-2 - analysis | Bridged-Ring Compounds - administration & dosage | Care and treatment | Breast cancer | Metastasis | Patient outcomes | Analysis
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue 3, pp. 534 - 542
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 09/2016, Volume 23, Issue 9, pp. 1565 - 1576
Necroptosis is a caspase-independent form of cell death that is triggered by activation of the receptor interacting serine/threonine kinase 3 (RIPK3) and... 
MYOCARDIAL-INFARCTION | RECEPTOR-INTERACTING PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOMAIN-LIKE PROTEIN | REPERFUSION INJURY | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | MEDIATES NECROPTOSIS | TNF-ALPHA | NECROPTOTIC CELL-DEATH | NF-KAPPA-B | CELL BIOLOGY | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Inflammation - pathology | Protein Kinases - genetics | Sepsis - etiology | Apoptosis - drug effects | Colitis - pathology | Male | Inflammation - metabolism | Sepsis - pathology | Sepsis - metabolism | Colitis - chemically induced | Female | Protein Kinases - deficiency | Reperfusion Injury - metabolism | Disease Models, Animal | Systemic Inflammatory Response Syndrome - metabolism | Lipopolysaccharides - toxicity | Reperfusion Injury - pathology | Mice, Inbred C57BL | Ceruletide - toxicity | Reperfusion Injury - mortality | Pancreatitis - chemically induced | Dextran Sulfate - toxicity | Mice, Knockout | Tumor Necrosis Factor alpha-Induced Protein 3 - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Systemic Inflammatory Response Syndrome - pathology | Animals | Colitis - metabolism | Pancreatitis - pathology | Systemic Inflammatory Response Syndrome - etiology | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Pancreatitis - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Tumor Necrosis Factor alpha-Induced Protein 3 - deficiency | Original Paper
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 1, pp. 78 - 89
Summary Background Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor,... 
Hematology, Oncology and Palliative Medicine | BIBF 1120 | DES CANCERS | INTERGROUP TRIAL | LABEL DOSE-ESCALATION | CISPLATIN | ONCOLOGY | BEVACIZUMAB | TRIPLE ANGIOKINASE INHIBITOR | CARBOPLATIN PLUS PACLITAXEL | III TRIAL | MAINTENANCE THERAPY | Humans | Middle Aged | Ovarian Neoplasms - pathology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Response Evaluation Criteria in Solid Tumors | Diarrhea - chemically induced | Cytoreduction Surgical Procedures | Indoles - administration & dosage | Young Adult | Peritoneal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Carcinoma - pathology | Neutropenia - chemically induced | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Fallopian Tube Neoplasms - drug therapy | Carcinoma - drug therapy | Peritoneal Neoplasms - pathology | Double-Blind Method | Carcinoma - surgery | Peritoneal Neoplasms - surgery | Anemia - chemically induced | Carboplatin - administration & dosage | Fallopian Tube Neoplasms - pathology | Thrombocytopenia - chemically induced | Disease Progression | Disease-Free Survival | Indoles - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Fallopian Tube Neoplasms - surgery | Intention to Treat Analysis | Aged | Neoplasm Staging | Ovarian Neoplasms - surgery | Clinical trials | Chemotherapy | Hospitals | Growth factors | Cancer | Ovarian cancer | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2011, Volume 121, Issue 10, pp. 4003 - 4014