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1. Full Text Might SARS-CoV-2 Have Arisen via Serial Passage through an Animal Host or Cell Culture? A potential explanation for much of the novel coronavirus' distinctive genome
by Sirotkin, Karl and Sirotkin, Dan
BioEssays, ISSN 0265-9247, 10/2020, Volume 42, Issue 10, pp. e2000091 - e2000091
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Amino Acid Sequence | Pandemics | Spike Glycoprotein, Coronavirus - genetics | Spike Glycoprotein, Coronavirus - metabolism | Humans | Pneumonia, Viral - etiology | Gain of Function Mutation - genetics | Betacoronavirus - growth & development | Zoonoses - transmission | Zoonoses - virology | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | Angiotensin-Converting Enzyme 2 | SARS-CoV-2 | Animals | Peptidyl-Dipeptidase A - metabolism | Protein Binding | Coronavirus Infections - etiology | Serial Passage | Betacoronavirus - genetics | Severe acute respiratory syndrome coronavirus 2 | Cell culture | Etiology | Peptidyl-dipeptidase A | Severe acute respiratory syndrome | Viral diseases | Angiotensin | Furin | Questions | Coronaviruses | Zoonoses | Index Medicus
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2. Full Text Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage
by Lin, Chun-Ming and Hou, Yixuan and Marthaler, Douglas G and Gao, Xiang and Liu, Xinsheng and Zheng, Lanlan and Saif, Linda J and Wang, Qiuhong
Veterinary microbiology, ISSN 0378-1135, 03/2017, Volume 201, pp. 62 - 71
Attenuation | Porcine epidemic diarrhea virus | Cell culture adaptation | Genome | Sequence analysis | Veterinary Sciences | Life Sciences & Biomedicine | Microbiology | Science & Technology | Immunogenicity, Vaccine | Chlorocebus aethiops | Porcine epidemic diarrhea virus - pathogenicity | Swine Diseases - virology | Genomics | Virulence | Cell Culture Techniques - veterinary | Diarrhea - virology | Diarrhea - veterinary | Porcine epidemic diarrhea virus - genetics | Antigens, Viral - immunology | Serial Passage - veterinary | Animals | Coronavirus Infections - veterinary | Coronavirus Infections - virology | Swine | Porcine epidemic diarrhea virus - immunology | Viral Vaccines | Vaccines, Attenuated | Vero Cells | Diarrhea | Antigens | Epidemics | Analysis | Virulence (Microbiology) | Membrane proteins | Cell culture | Neonates | Amino acids | Viruses | Suckling behavior | Proteins | Intestine | Syncytia | Lesions | Growth kinetics | Transmissible gastroenteritis | Studies | Hogs | Molecular modelling | Kinetics | Economic impact | Colostrum | Protein structure | Pork | Index Medicus
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3. Full Text Evolution of newcastle disease virus quasispecies diversity and enhanced virulence after passage through chicken air sacs
by Meng, Chunchun and Qiu, Xusheng and Yu, Shengqing and Li, Chuanfeng and Sun, Yingjie and Chen, Zongyan and Liu, Kaichun and Zhang, Xiangle and Tan, Lei and Song, Cuiping and Liu, Guangqing and Ding, Chan
Journal of virology, ISSN 0022-538X, 2016, Volume 90, Issue 4, pp. 2052 - 2063
Life Sciences & Biomedicine | Science & Technology | Virology | Newcastle disease virus - pathogenicity | Genome, Viral | Poultry Diseases - pathology | Newcastle Disease - virology | Virulence | Adaptation, Biological | Molecular Sequence Data | Poultry Diseases - virology | Sequence Analysis, DNA | Ducks | Genetic Variation | Newcastle disease virus - growth & development | Animals | Chickens | Newcastle disease virus - genetics | Histocytochemistry | Survival Analysis | Air Sacs - virology | Brain - pathology | Viral Tropism | Serial Passage | Newcastle Disease - pathology | Index Medicus
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4. Full Text In vitro passage alters virulence, immune activation and proteomic profiles of Burkholderia pseudomallei
by Duangurai, Taksaon and Reamtong, Onrapak and Rungruengkitkun, Amporn and Srinon, Varintip and Boonyuen, Usa and Limmathurotsakul, Direk and Chantratita, Narisara and Pumirat, Pornpan
Scientific reports, ISSN 2045-2322, 05/2020, Volume 10, Issue 1, pp. 8320 - 8320
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Moths - microbiology | Humans | Virulence | Proteome | Gene Expression Profiling | Animals | Burkholderia pseudomallei - immunology | Burkholderia pseudomallei - pathogenicity | Cell Line, Tumor | Burkholderia pseudomallei - physiology | HeLa Cells | Serial Passage | Cytokines - immunology | Clinical isolates | Phenotypes | Immune response | Immunogenicity | Strains (organisms) | Index Medicus
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5. Full Text Host Adaptation of a Wolbachia Strain after Long-Term Serial Passage in Mosquito Cell Lines
by Conor J. McMeniman and Amanda M. Lane and Amy W. C. Fong and Denis A. Voronin and Iñaki Iturbe-Ormaetxe and Ryuichi Yamada and Elizabeth A. McGraw and Scott L. O'Neill
Applied and Environmental Microbiology, ISSN 0099-2240, 11/2008, Volume 74, Issue 22, pp. 6963 - 6969
Life Sciences & Biomedicine | Microbiology | Biotechnology & Applied Microbiology | Science & Technology | Cell Line | Virulence | Adaptation, Biological | Male | Wolbachia - physiology | Aedes | Gram-Negative Bacterial Infections - microbiology | Anopheles | Drosophila melanogaster - microbiology | Animals | Female | Wolbachia - pathogenicity | Serial Passage | Aedes albopictus | Wolbachia | Diseases and pests | Drosophila | Analysis | Host-parasite relationships | Environmental aspects | Genetic aspects | Genotype & phenotype | Bacteria | Genetics | Insects | Bacteriology | Cells | Index Medicus | Invertebrate Microbiology
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6. Full Text Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein
by Davidson, Andrew D and Williamson, Maia Kavanagh and Lewis, Sebastian and Shoemark, Deborah and Carroll, Miles W and Heesom, Kate J and Zambon, Maria and Ellis, Joanna and Lewis, Philip A and Hiscox, Julian A and Matthews, David A
Genome medicine, ISSN 1756-994X, 07/2020, Volume 12, Issue 1, pp. 68 - 68
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Sequence Deletion | Phosphorylation | Chlorocebus aethiops | Spike Glycoprotein, Coronavirus - genetics | Betacoronavirus - growth & development | Gene Expression Profiling - methods | Betacoronavirus - metabolism | Tandem Mass Spectrometry | SARS-CoV-2 | Animals | Sequence Analysis, RNA | Proteomics - methods | Serial Passage | Betacoronavirus - genetics | Vero Cells | Animal models | Transcription | Virulence | Viruses | Genomes | Gene deletion | Proteins | Maps | Clonal deletion | Furin | Data analysis | Nucleotide sequence | Mass spectroscopy | Glycoproteins | Coronaviruses | Ribonucleic acid--RNA | Gene expression | Morbidity | Severe acute respiratory syndrome coronavirus 2 | Adenoviruses | Proteomics | Software | Open reading frames | Spike glycoprotein | Viral infections | Index Medicus
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7. Full Text In vitro selection, via serial passage, of clostridium difficile mutants with reduced susceptibility to fidaxomicin or vancomycin
by Leeds, Jennifer A and Sachdeva, Meena and Mullin, Steve and Whitney Barnes, S and Ruzin, Alexey
Journal of antimicrobial chemotherapy, ISSN 0305-7453, 01/2014, Volume 69, Issue 1, pp. 41 - 44
Marr | Rna polymerase | LFF571 | Murg | Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Genome, Bacterial | DNA, Bacterial - isolation & purification | Humans | Selection, Genetic | Cell Wall - genetics | Drug Resistance, Bacterial | DNA, Bacterial - chemistry | DNA-Directed RNA Polymerases - genetics | Sequence Analysis, DNA | Microbial Sensitivity Tests | DNA, Bacterial - genetics | DNA Mutational Analysis | Vancomycin - pharmacology | Clostridium difficile - growth & development | Anti-Bacterial Agents - pharmacology | Thiazoles - pharmacology | Mutation | Aminoglycosides - pharmacology | Serial Passage | Clostridium difficile - drug effects | Gram-positive bacteria | Medical treatment | Cells | Deoxyribonucleic acid--DNA | Index Medicus
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8. Full Text In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract
by Chen, Chaoqun and Zhou, Zhou and Conrad, Turner and Yang, Zhangsheng and Dai, Jin and Li, Zhongyu and Wu, Yimou and Zhong, Guangming
Infection and immunity, ISSN 0019-9567, 2015, Volume 83, Issue 5, pp. 1881 - 1892
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Reproductive Tract Infections - microbiology | Reproductive Tract Infections - pathology | Humans | Virulence | Chlamydia muridarum - genetics | Selection, Genetic | DNA, Bacterial - chemistry | Mice, Inbred C3H | Bacterial Adhesion | Chlamydia Infections - pathology | Animals | Chlamydia Infections - microbiology | DNA, Bacterial - genetics | Chlamydia muridarum - pathogenicity | Female | Chlamydia muridarum - physiology | High-Throughput Nucleotide Sequencing | HeLa Cells | Serial Passage | Index Medicus | Molecular Pathogenesis
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9. Full Text Long-term passage of duck Tembusu virus in BHK-21 cells generates a completely attenuated and immunogenic population with increased genetic diversity
by Zhang, Lijiao and Sun, Mengxu and Zhang, Qingshui and Wang, Jun and Cao, Yanxin and Cui, Shangjin and Su, Jingliang
Vaccine, ISSN 0264-410X, 01/2020, Volume 38, Issue 4, pp. 933 - 941
Duck | Live-attenuated vaccine | Virus diversity (quasi-species) | Tembusu virus | Flavivirus | Serial passage | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Flavivirus Infections - immunology | Cell Line | Cricetinae | Flavivirus Infections - prevention & control | Flavivirus - immunology | Vaccination | Poultry Diseases - virology | Flavivirus Infections - veterinary | Ducks | Viral Vaccines - administration & dosage | Genetic Variation | Vaccines, Attenuated - immunology | Animals | Poultry Diseases - prevention & control | Poultry Diseases - immunology | Female | Viral Vaccines - immunology | Amino Acid Substitution | Cell culture | E protein | Virulence | Antibodies | Amino acids | Viruses | Genomes | Infections | Single-nucleotide polymorphism | Vaccines | Nucleotides | Aquatic birds | Population genetics | Ethics | Infectivity | Penicillin | Attenuation | Genetics | Deoxyribonucleic acid--DNA | Encephalitis | Pathogens | Waterfowl | Genetic diversity | Stability analysis | RNA polymerase | Disease control | Pathogenicity | Immunogenicity | Control stability | Mutation | Laboratory animals | Fitness | Index Medicus
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10. Full Text Genetic Changes at the Glycoprotein Editing Site Associated With Serial Passage of Sudan Virus
by Kendra J. Alfson and Laura E. Avena and Michael W. Beadles and Heather Menzie and Jean L. Patterson and Ricardo Carrion and Anthony Griffiths
The Journal of infectious diseases, ISSN 0022-1899, 10/2015, Volume 212, Issue suppl 2, pp. S295 - S304
PATHOGENESIS | Sudan virus | cell culture adaptation | RNA editing | glycoprotein | editing site | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Glycoproteins - genetics | Serial Passage - methods | Vero Cells - virology | RNA Editing - genetics | Genome, Viral - genetics | Sudan | Cercopithecus aethiops | Ebolavirus - pathogenicity | Ebolavirus - genetics | Haplorhini | Animals | Virulence - genetics | Hemorrhagic Fever, Ebola - virology | Viral Load - methods | Index Medicus | Abridged Index Medicus
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