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Diabetes, ISSN 0012-1797, 03/2018, Volume 67, Issue 3, pp. 423 - 436
Progressive failure of insulin-producing beta-cells is the central event leading to diabetes, but the signaling networks controlling beta-cell fate remain... 
APOPTOSIS | FACTOR SRSF6 | GLUCOSE | ENDOCRINOLOGY & METABOLISM | GLIS3 | DEATH | LOCI | DIFFERENTIATION | STRESS | TYPE-1 | IDENTIFICATION | Mitochondria - enzymology | Phosphorylation | Alternative Splicing | Humans | Gene Expression Profiling | Phosphoproteins - antagonists & inhibitors | Serine-Arginine Splicing Factors - metabolism | Phosphoproteins - metabolism | Serine-Arginine Splicing Factors - genetics | Phosphoproteins - chemistry | MAP Kinase Signaling System | Insulin-Secreting Cells - metabolism | RNA Interference | Serine-Arginine Splicing Factors - chemistry | Insulin-Secreting Cells - cytology | Protein Interaction Domains and Motifs | Insulin Secretion | bcl-2-Associated X Protein - genetics | Cell Line | Cell Survival | Cells, Cultured | Gene Expression Regulation | bcl-2-Associated X Protein - metabolism | Bcl-2-Like Protein 11 - genetics | Mitochondria - metabolism | Phosphoproteins - genetics | Serine-Arginine Splicing Factors - antagonists & inhibitors | Insulin - metabolism | Bcl-2-Like Protein 11 - metabolism | Endoplasmic Reticulum Stress | Protein Processing, Post-Translational | Apoptosis | RNA sequencing | Control | Usage | Blood sugar | Diabetes | B cells | Research | Risk factors | Alternative splicing | Transcription factors | Cell survival | Bax protein | Secretion | Diabetes mellitus | c-Jun protein | Kinases | Ribonucleic acid--RNA | Insulin | Proteins | Beta cells | Survival analysis | Mitochondria | Cell fate | Cell death | Pancreas | Endoplasmic reticulum | Splicing factors | BIM protein | Index Medicus | Abridged Index Medicus | 0709 | Islet Studies
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 44, pp. 18240 - 18255
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 11/2018, Volume 46, Issue 21, pp. 11357 - 11369
Abstract Aberrant splicing is a hallmark of leukemias with mutations in splicing factor (SF)-encoding genes. Here we investigated its prevalence in pediatric... 
MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | P53-BETA | C-MYC | P53 ISOFORMS | HNRNP A1 | MUTATIONS | BINDING-SITES | TRANSLATION | T-CELLS | ANTIGEN | 5'-Nucleotidase - genetics | RNA Helicases - metabolism | RNA, Small Interfering - genetics | Alternative Splicing | Exons | Humans | Serine-Arginine Splicing Factors - metabolism | Serine-Arginine Splicing Factors - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Trans-Activators - genetics | Adult | RNA Helicases - genetics | B-Lymphocytes - pathology | 3' Untranslated Regions | DEAD-box RNA Helicases - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Child | B-Lymphocytes - metabolism | Ribonuclease III - genetics | Ribonuclease III - metabolism | Introns | Bone Marrow Cells - pathology | Gene Expression Regulation, Leukemic | Heterogeneous Nuclear Ribonucleoprotein A1 - genetics | Nonsense Mediated mRNA Decay | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Serine-Arginine Splicing Factors - antagonists & inhibitors | DEAD-box RNA Helicases - genetics | Cell Line, Tumor | Trans-Activators - metabolism | Heterogeneous Nuclear Ribonucleoprotein A1 - metabolism | Primary Cell Culture | 5'-Nucleotidase - metabolism | Bone Marrow Cells - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Genomics
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2017, Volume 45, Issue 7, pp. 4202 - 4216
A critical step in exon definition is the recognition of a proper splice donor (5΄ss) by the 5' end of U1 snRNA. In the selection of appropriate 5΄ss,... 
RNA Splice Sites | Exons | Humans | RNA, Small Nuclear - chemistry | Regulatory Sequences, Ribonucleic Acid | Serine-Arginine Splicing Factors - metabolism | HeLa Cells | Mutation | Fibrinogen - genetics | Index Medicus | RNA
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2464 - 21
Journal Article
Journal Article