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Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2011, Volume 54, Issue 9, pp. 3206 - 3221
The synthesis and structure-activity relationship of a novel series of compounds with combined effects on 5-HT3A and 5-HT1A receptors and on the serotonin... 
FREELY MOVING RATS | ARYL BROMIDES | SEROTONIN REUPTAKE INHIBITORS | IN-VIVO MICRODIALYSIS | CHEMISTRY, MEDICINAL | PALLADIUM-CATALYZED SYNTHESIS | 5-HT1A RECEPTORS | MOOD DISORDERS | DRUG DISCOVERY | FRONTAL-CORTEX | ANTIDEPRESSANT-LIKE BEHAVIOR | Xenopus | Humans | Microsomes, Liver - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Sulfides - chemistry | Serotonin 5-HT1 Receptor Agonists - pharmacology | Sulfides - chemical synthesis | Piperazines - chemistry | Structure-Activity Relationship | Hippocampus - drug effects | Serotonin Uptake Inhibitors - chemical synthesis | Receptors, Serotonin, 5-HT1 - metabolism | Serotonin 5-HT1 Receptor Agonists - chemistry | Antidepressive Agents - chemistry | Oocytes - drug effects | Antidepressive Agents - pharmacology | Radioligand Assay | Serotonin 5-HT3 Receptor Antagonists - chemistry | Receptor, Serotonin, 5-HT1A - metabolism | Depressive Disorder, Major - drug therapy | Sulfides - pharmacology | Cell Line | Recombinant Proteins - antagonists & inhibitors | Drug Partial Agonism | Drug Stability | Rats | Serotonin Uptake Inhibitors - chemistry | Serotonin 5-HT1 Receptor Agonists - chemical synthesis | Recombinant Proteins - agonists | Piperazines - pharmacology | Receptors, Serotonin - metabolism | Serotonin 5-HT3 Receptor Antagonists - chemical synthesis | Serotonin Plasma Membrane Transport Proteins - metabolism | Hippocampus - metabolism | Animals | Oocytes - physiology | Receptors, Serotonin, 5-HT3 - metabolism | Serotonin - metabolism | Antidepressive Agents - chemical synthesis | Piperazines - chemical synthesis | Serotonin 5-HT3 Receptor Antagonists - pharmacology | In Vitro Techniques | Serotonin Uptake Inhibitors - pharmacology | Index Medicus
Journal Article
2006, 1. Aufl., The receptors, ISBN 9781588295682, xvii, 618
A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for... 
Receptors | Serotonin | Physiological effect | Serotoninergic mechanisms | Other branches of medicine | Pharmacy
Book
Pain, ISSN 0304-3959, 08/2007, Volume 130, Issue 3, pp. 235 - 248
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2002, Volume 8, Issue 10, pp. 1129 - 1135
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2005, Volume 25, Issue 49, pp. 11231 - 11238
Serotonin (5-hydroxytryptamine; 5-HT) plays key roles in sleep-wakefulness regulation. Evidence indicates that 5-HT2 receptors are involved mainly in non-rapid... 
Apnea | Sleep | receptors | Serotonin | Knock-out mice | EEG | Depression | Serotonergic | Mice | 5-HT | Respiration | Sleep deprivation | HOMEOSTASIS | ANTAGONIST | PHARMACOLOGICAL CHARACTERIZATION | respiration | mice | PARADOXICAL SLEEP | NEUROSCIENCES | serotonergic | sleep | apnea | serotonin | sleep deprivation | ANIMAL-MODEL | depression | 5-HT2 receptors | knock-out mice | EXPRESSION | MODULATION | REM-SLEEP | Wakefulness - drug effects | Wakefulness - genetics | Adaptation, Physiological - physiology | Male | Sleep Deprivation - genetics | Sleep - genetics | Serotonin Antagonists - pharmacology | Sleep - drug effects | Sleep Deprivation - metabolism | Mice, Knockout | Serotonin Receptor Agonists - pharmacology | Pulmonary Ventilation - genetics | Serotonin 5-HT2 Receptor Antagonists | Receptor, Serotonin, 5-HT2A - physiology | Animals | Receptors, Serotonin, 5-HT2 - genetics | Adaptation, Physiological - genetics | Receptors, Serotonin, 5-HT2 - deficiency | Receptor, Serotonin, 5-HT2A - deficiency | Pulmonary Ventilation - physiology | Wakefulness - physiology | Serotonin 5-HT2 Receptor Agonists | Sleep - physiology | Index Medicus | Adaptation, Physiological | Sleep Deprivation | Pulmonary Ventilation | Neurons and Cognition | Neurobiology | Serotonin Agonists | Receptor, Serotonin, 5-HT2A | Life Sciences | Receptors, Serotonin, 5-HT2 | Wakefulness | Serotonin Antagonists | Behavioral | Systems | Cognitive
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1537 - 1541
The serotonin transporter (SERT) ensures the recapture of serotonin and is the pharmacological target of selective serotonin reuptake inhibitor (SSRI)... 
Receptors | MicroRNA | Serotonin agents | Neurons | Antidepressants | Serotonin receptors | REPORTS | Cell lines | Serotonin plasma membrane transport proteins | Adrenergic neurons | Locus coeruleus | LOCUS-COERULEUS | CELLS | RECEPTOR | RECOGNITION | RAT | MULTIDISCIPLINARY SCIENCES | Up-Regulation | Protein Biosynthesis | Humans | MicroRNAs - metabolism | Nerve Growth Factors - metabolism | Antidepressive Agents, Second-Generation - administration & dosage | Raphe Nuclei - metabolism | Serotonin Plasma Membrane Transport Proteins - genetics | Neurons - metabolism | 3' Untranslated Regions | Neurons - drug effects | Serotonin Uptake Inhibitors - metabolism | Cell Line | Fluoxetine - pharmacology | S100 Calcium Binding Protein beta Subunit | MicroRNAs - administration & dosage | Depression | S100 Proteins - metabolism | Antidepressive Agents, Second-Generation - pharmacology | Serotonin Plasma Membrane Transport Proteins - metabolism | Animals | Norepinephrine - metabolism | Raphe Nuclei - drug effects | Serotonin Uptake Inhibitors - administration & dosage | Serotonin - metabolism | Fluoxetine - administration & dosage | Fluoxetine - metabolism | Mice | MicroRNAs - genetics | HeLa Cells | Antidepressive Agents, Second-Generation - metabolism | Serotonin Uptake Inhibitors - pharmacology | Locus Coeruleus - metabolism | Pharmacogenetics | Serotonin | Physiological aspects | Serotonin uptake inhibitors | Dosage and administration | Research | Health aspects | Pharmacology | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2017, Volume 152, Issue 5, p. S13-S14
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2016, Volume 26, Issue 8, pp. 1327 - 1337
Abstract The present study investigated interactions between the novel psychoactive tryptamines DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at... 
Internal Medicine | Psychiatry | DMT | Psilocybin | Tryptamines | LSD | Hallucinogens | Mescaline | DESIGNER CATHINONES | SEROTONIN TRANSPORTER | Psitocybin | DOSE-RESPONSE | MONOAMINE TRANSPORTER | PREPULSE INHIBITION | PSYCHIATRY | NEUROSCIENCES | CLINICAL NEUROLOGY | LYSERGIC-ACID DIETHYLAMIDE | HEAD-TWITCH RESPONSE | IN-VITRO | DOUBLE-BLIND | PHARMACOLOGICAL PROFILE | PHARMACOLOGY & PHARMACY | NIH 3T3 Cells | Membrane Transport Modulators - chemistry | Receptor, Serotonin, 5-HT2A - genetics | Vesicular Monoamine Transport Proteins - metabolism | Receptor, Serotonin, 5-HT2B - metabolism | Humans | Receptor, Serotonin, 5-HT2C - metabolism | Serotonin 5-HT2 Receptor Agonists - pharmacology | Structure-Activity Relationship | Receptor, Serotonin, 5-HT2A - chemistry | Receptor, Serotonin, 5-HT2B - genetics | Tryptamines - pharmacology | Membrane Transport Modulators - pharmacology | Psychotropic Drugs - pharmacology | HEK293 Cells | Molecular Structure | Psychotropic Drugs - metabolism | Radioligand Assay | Serotonin 5-HT2 Receptor Agonists - metabolism | Recombinant Proteins - metabolism | Cell Survival - drug effects | Tryptamines - chemistry | Hallucinogens - pharmacology | Hallucinogens - metabolism | Vesicular Monoamine Transport Proteins - antagonists & inhibitors | Hallucinogens - chemistry | Recombinant Proteins - chemistry | Psychotropic Drugs - chemistry | Serotonin 5-HT2 Receptor Agonists - chemistry | Receptor, Serotonin, 5-HT2B - chemistry | Membrane Transport Modulators - metabolism | Animals | Tryptamines - metabolism | Receptor, Serotonin, 5-HT2C - chemistry | Vesicular Monoamine Transport Proteins - genetics | Ligands | Mice | Receptor, Serotonin, 5-HT2C - genetics | Biogenic Monoamines - metabolism | Kinetics | Receptor, Serotonin, 5-HT2A - metabolism | Cytokinins | Alkaloids | Hallucinogenic drugs | Comparative analysis | Index Medicus
Journal Article
2008, Progress in brain research, ISBN 0444532358, Volume 172., xv, 665 p. [6] p. of plates
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the... 
Neurochemistry | Neurotransmitters | Dopamine | Serotonin | Neurochimie
Book
Clinical Nutrition, ISSN 0261-5614, 09/2017, Volume 36, pp. S60 - S60
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2009, Volume 48, Issue 1, pp. 220 - 229
Abstract 5-hydroxytryptamine-4 (5-HT4 ) receptors have been proposed to contribute to the generation of atrial fibrillation in human atrial myocytes, but it is... 
Cardiovascular | Serotonin | Syncytial properties | Calcium current | Cardiomyocytes | cAMP | Gap junction | Connexin | Cx40 | Cx43 | Cx45 | 5-HT2B | 5-HT4a | 5-HT4b | 5-HT2A | CARDIAC & CARDIOVASCULAR SYSTEMS | 5-HYDROXYTRYPTAMINE | CARDIAC MYOCYTES | HEART-FAILURE | CELL BIOLOGY | NATRIURETIC-PEPTIDE | CA2+ CURRENT | CONNEXINS | EXPRESSION | HUMAN ATRIAL MYOCYTES | para-Aminobenzoates | Gap Junctions - metabolism | Receptor, Serotonin, 5-HT2A - genetics | Rats, Wistar | Receptor, Serotonin, 5-HT2B - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Receptors, Serotonin, 5-HT4 - genetics | Serotonin - pharmacology | Serotonin 5-HT4 Receptor Antagonists | Serotonin 5-HT2 Receptor Antagonists | Receptor, Serotonin, 5-HT2B - genetics | Piperidines - pharmacology | Indoles - pharmacology | Phosphorylation - drug effects | Animals, Newborn | Heart Atria - cytology | Cells, Cultured | Rats | Adenylyl Cyclases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Serotonin Antagonists - pharmacology | Sulfonamides - pharmacology | Blotting, Western | Connexins - metabolism | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Serotonin Agents - pharmacology | Aminobenzoates - pharmacology | Myocytes, Cardiac - metabolism | Receptors, Serotonin, 5-HT4 - metabolism | Receptor, Serotonin, 5-HT2C - genetics | Gap Junctions - drug effects | In Vitro Techniques | Receptor, Serotonin, 5-HT2A - metabolism | Proteins | Atrial fibrillation | Index Medicus | Phosphorylation | Serotonin Agents | Aminobenzoic Acids | Cellular Biology | Gap Junctions | Life Sciences | Piperidines | Indoles | Cardiology and cardiovascular system | Cell Behavior | Myocytes, Cardiac | Heart Atria | Biochemistry, Molecular Biology | Adenylate Cyclase | Receptor, Serotonin, 5-HT2B | Receptor, Serotonin, 5-HT2A | Receptor, Serotonin, 5-HT2C | Receptors, Serotonin, 5-HT4 | Human health and pathology | Sulfonamides | Serotonin Antagonists | Connexins | Molecular biology
Journal Article
Journal of serotonin research, ISSN 1350-7702, 1994
Journal
Behavioural Brain Research, ISSN 0166-4328, 03/2016, Volume 301, p. 132
* Subchronic tandospironeinduced prolonged reversalof PCP-induced NOR deficit. * Subchronic lurasidone, an atypical APD, induced prolonged reversal of NOR... 
Serotonin
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 01/2015, Volume 277, pp. 1 - 2
Journal Article
Journal of Urology, ISSN 0022-5347, 04/2015, Volume 193, Issue 4S, p. e361-e362
Journal Article
Neuropharmacology, ISSN 0028-3908, 08/2013, Volume 71, pp. 83 - 97
Serotonin (5-HT) is a neurotransmitter that is involved in many behavioral functions, including the organization of defense, and its putative pathological... 
Fear | Zebrafish | Anxiety | Serotonin | Scototaxis | Geotaxis | 5-HYDROXYTRYPTAMINE RELEASE | RAT | 5-HT1A RECEPTOR ANTAGONISTS | REUPTAKE INHIBITORS | DORSAL RAPHE | ADULT ZEBRAFISH | ELEVATED PLUS-MAZE | T-MAZE | NEUROSCIENCES | IN-VIVO | PHARMACOLOGY & PHARMACY | BRAIN | Anti-Anxiety Agents - administration & dosage | Fenclonine - administration & dosage | Spiro Compounds - therapeutic use | Anxiety - drug therapy | Piperidones - therapeutic use | Serotonin - chemistry | Brain - metabolism | Pyridines - adverse effects | Fenclonine - adverse effects | Behavior, Animal - drug effects | Hyperkinesis - chemically induced | Neurons - metabolism | Serotonin 5-HT1 Receptor Antagonists - administration & dosage | Anti-Anxiety Agents - therapeutic use | Buspirone - therapeutic use | Fluoxetine - adverse effects | Disease Models, Animal | Pyridines - administration & dosage | Nerve Tissue Proteins - agonists | Piperazines - therapeutic use | Piperazines - adverse effects | Extracellular Fluid - drug effects | Brain - drug effects | Serotonin Uptake Inhibitors - administration & dosage | Fluoxetine - administration & dosage | Piperazines - administration & dosage | Fenclonine - therapeutic use | Spiro Compounds - administration & dosage | Piperidones - adverse effects | Hyperkinesis - metabolism | Spiro Compounds - adverse effects | Dose-Response Relationship, Drug | Buspirone - administration & dosage | Protein Isoforms - metabolism | Protein Isoforms - agonists | Anti-Anxiety Agents - adverse effects | Buspirone - adverse effects | Fluoxetine - therapeutic use | Neurons - drug effects | Anxiety - metabolism | Pyridines - therapeutic use | Nerve Tissue Proteins - antagonists & inhibitors | Serotonin Uptake Inhibitors - therapeutic use | Serotonin Uptake Inhibitors - adverse effects | Serotonin 5-HT1 Receptor Agonists - therapeutic use | Serotonin 5-HT1 Receptor Agonists - adverse effects | Serotonin 5-HT1 Receptor Antagonists - adverse effects | Nerve Tissue Proteins - metabolism | Piperidones - administration & dosage | Extracellular Fluid - metabolism | Serotonin 5-HT1 Receptor Antagonists - therapeutic use | Animals | Serotonin - metabolism | Serotonin 5-HT1 Receptor Agonists - administration & dosage | Anxiety - chemically induced | Protein Isoforms - antagonists & inhibitors | Phenols | Buspirone hydrochloride | Fluoxetine | Index Medicus
Journal Article