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Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 6, pp. 1008 - 1015
The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked... 
PULMONARY-HYPERTENSION | PERMEABILITY | 5-HYDROXYTRYPTAMINE | ENDOTHELIAL-CELLS | MAST-CELLS | P-SELECTIN | RECEPTOR | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | VON-WILLEBRAND-FACTOR | SELECTIN-DEFICIENT MICE | Blood Platelets - immunology | Endothelium, Vascular - drug effects | Male | Shock, Septic - immunology | Lipopolysaccharides | Serotonin - blood | Inflammation - metabolism | L-Selectin - immunology | Leukocytosis - metabolism | Weibel-Palade Bodies - metabolism | Chemotaxis - immunology | Neutrophils - metabolism | Serotonin - immunology | Serotonin Uptake Inhibitors - immunology | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Fluoxetine - pharmacology | Acute Disease | Neutrophils - drug effects | Leukocytosis - immunology | Chemotaxis - drug effects | Mice, Knockout | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Mice | Serotonin Uptake Inhibitors - pharmacology | Leukocyte Rolling - drug effects | Weibel-Palade Bodies - immunology | Histamine - immunology | L-Selectin - metabolism | Flow Cytometry | Tryptophan Hydroxylase - deficiency | Blood Platelets - drug effects | Fluoxetine - immunology | Shock, Septic - genetics | Leukocyte Rolling - genetics | Histamine - pharmacology | Shock, Septic - chemically induced | Mice, Inbred C57BL | Kaplan-Meier Estimate | Neutrophils - immunology | Inflammation - immunology | Leukocyte Rolling - immunology | Tryptophan Hydroxylase - genetics | Weibel-Palade Bodies - drug effects | Animals | Serotonin - metabolism | Inflammation - genetics | Leukocytosis - genetics | Phagocytes, Granulocytes, and Myelopoiesis | Platelets and Thrombopoiesis
Journal Article
Blood, ISSN 0006-4971, 04/2007, Volume 109, Issue 8, pp. 3139 - 3146
Although typically considered a neurotransmitter, there is substantial evidence that serotonin (5-HT) plays an important role in the pathogenesis of... 
IMMUNE-RESPONSE | IN-VITRO | DENDRITIC CELLS | MESSENGER-RNA | LYMPHOCYTE | TRYPTOPHAN-HYDROXYLASE | CONTACT SENSITIVITY | RELEASE | HEMATOLOGY | EXPRESSION | DELAYED-TYPE HYPERSENSITIVITY | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | I-kappa B Proteins - immunology | Male | Autocrine Communication - drug effects | Receptors, Serotonin - immunology | I-kappa B Proteins - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Enzyme Activation - immunology | Signal Transduction - immunology | Inflammation - metabolism | Lymphocyte Activation - immunology | Autocrine Communication - immunology | Protein Processing, Post-Translational - drug effects | T-Lymphocytes - metabolism | Phosphorylation - drug effects | Receptor, Serotonin, 5-HT1B - biosynthesis | Protein Processing, Post-Translational - immunology | Serotonin - immunology | Fenclonine - pharmacology | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | NF-KappaB Inhibitor alpha | Gene Expression Regulation - immunology | Cells, Cultured | Inflammation - immunology | Enzyme Activation - drug effects | Receptors, Serotonin - metabolism | Gene Expression Regulation - drug effects | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Serotonin - metabolism | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Receptor, Serotonin, 5-HT1B - immunology | Mitogen-Activated Protein Kinase 1 - metabolism | Plenary Paper
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1416 - 1423
Increasing evidence suggests an important role for platelets and their products (eg, platelet factor 4, β-thromboglobulin, RANTES, thromboxane, or serotonin)... 
Allergy and Immunology | TH2 sensitization | dendritic cells | asthma pathophysiology | Platelets | leukocyte recruitment | airway remodeling | T | 2 sensitization | T(H)2 sensitization | IMMUNE CELLS | IMMUNOLOGY | MURINE MODEL | NEUTROPHIL EXTRACELLULAR TRAPS | ALLERGY | INDUCED BRONCHIAL HYPERRESPONSIVENESS | P-SELECTIN | HOST-DEFENSE | DOUBLE-BLIND | ASTHMA | Blood Platelets - pathology | Blood Platelets - immunology | Bronchial Hyperreactivity - immunology | Dendritic Cells - immunology | Humans | Platelet Activation - immunology | Platelet Factor 4 - immunology | Dendritic Cells - pathology | Bronchial Hyperreactivity - genetics | Airway Remodeling - immunology | beta-Thromboglobulin - immunology | Thromboxanes - metabolism | Bronchial Hyperreactivity - physiopathology | Asthma - immunology | Bronchoconstriction - immunology | Platelet Aggregation - genetics | Serotonin - immunology | Dendritic Cells - metabolism | Platelet Factor 4 - genetics | Gene Expression | Asthma - physiopathology | Platelet Aggregation - immunology | beta-Thromboglobulin - genetics | Asthma - genetics | Platelet Activation - genetics | Blood Platelets - metabolism | Serotonin - metabolism | Chemokine CCL5 - genetics | Thromboxanes - immunology | Chemokine CCL5 - immunology | Inflammation | Asthma | Free radicals | Motility | Disease | Serotonin | Pathogenesis | Smooth muscle | Thrombosis | Allergies | Inflammatory diseases | Recruitment | Hypotheses | Blood platelets | Ligands
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2013, Volume 190, Issue 5, pp. 2301 - 2310
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 6, pp. 1271 - 1279.e10
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 07/2017, Volume 23, Issue 28, pp. 5068 - 5085
Inflammatory bowel disease (IBD) is a chronic recurrent condition whose etiology is unknown, and it includes ulcerative colitis, Crohn's disease, and... 
Enteric nervous system | Musashi-1 | Stem cells | Inflammatory bowel Disease | Immune cells | Enteroendocrine cells | Neurogenin 3 | DEXTRAN SULFATE SODIUM | VASOACTIVE-INTESTINAL-PEPTIDE | NATURAL ENDOGENOUS LIGAND | Inflammatory bowel disease | NEUROPEPTIDE-Y NPY | SOMATOSTATIN RECEPTOR SUBTYPES | GLUCAGON-LIKE PEPTIDE-1 | PURINERGIC NEUROMUSCULAR-TRANSMISSION | COLONIC ENDOCRINE-CELLS | PERITONEAL-MACROPHAGE FUNCTIONS | HORMONE SECRETAGOGUE RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | Recurrence | Ghrelin - immunology | Prevalence | Neurosecretory Systems - cytology | Chromogranins - immunology | Humans | Inflammatory Bowel Diseases - immunology | Inflammatory Bowel Diseases - diagnosis | Neurosecretory Systems - immunology | Substance P - immunology | Amines - immunology | Neuropeptide Y - immunology | Neuropeptide Y - secretion | Gastrointestinal Tract - immunology | Chromogranins - metabolism | Inflammatory Bowel Diseases - epidemiology | Neuroendocrine Cells - secretion | Substance P - secretion | Neuroendocrine Cells - metabolism | Neuropeptide Y - antagonists & inhibitors | Serotonin - immunology | Disease Models, Animal | Somatostatin - secretion | Somatostatin - immunology | Substance P - antagonists & inhibitors | Vasoactive Intestinal Peptide - secretion | Gastrointestinal Microbiome | Serotonin Antagonists - therapeutic use | Chromogranins - secretion | Ghrelin - secretion | Ghrelin - metabolism | Animals | Vasoactive Intestinal Peptide - immunology | Gastrointestinal Tract - secretion | Quality of Life | Serotonin - secretion | Substance P - metabolism | Inflammatory Bowel Diseases - therapy | Neuroendocrine Cells - immunology | Review
Journal Article