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1. Full Text Rikkunshito, an Herbal Medicine, Suppresses Cisplatin-Induced Anorexia in Rats Via 5-HT2 Receptor Antagonism
by Takeda, Hiroshi and Sadakane, Chiharu and Hattori, Tomohisa and Katsurada, Takehiko and Ohkawara, Tatsuya and Nagai, Koichi and Asaka, Masahiro
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2008, Volume 134, Issue 7, pp. 2004 - 2013
Gastroenterology and Hepatology | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Receptor, Serotonin, 5-HT2B - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Body Weight - drug effects | Drugs, Chinese Herbal - pharmacology | Male | Stomach - metabolism | Drugs, Chinese Herbal - metabolism | Anorexia - physiopathology | Quinolines - pharmacology | Serotonin Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Serotonin 5-HT2 Receptor Antagonists | Chalcones - pharmacology | Dopamine Antagonists - metabolism | Receptors, Ghrelin - metabolism | Indoles - pharmacology | Stomach - innervation | Stomach - drug effects | Drugs, Chinese Herbal - therapeutic use | Flavones - pharmacology | Acylation | Disease Models, Animal | Antineoplastic Agents | Rats | Thiophenes - pharmacology | Anorexia - metabolism | Dopamine Antagonists - therapeutic use | Receptors, Ghrelin - drug effects | Piperazines - pharmacology | Rats, Sprague-Dawley | Vagotomy | Cisplatin | Ghrelin - metabolism | Eating - drug effects | Gastrointestinal Agents - pharmacology | Ghrelin - blood | Animals | Dopamine Antagonists - pharmacology | Aminopyridines - pharmacology | Serotonin - metabolism | Gastrointestinal Agents - therapeutic use | Anorexia - prevention & control | Hesperidin - pharmacology | Protein Binding | Anorexia - chemically induced | Oligopeptides - pharmacology | Gastrointestinal Agents - metabolism | Medicine, Botanic | Medicine, Herbal | Index Medicus | Abridged Index Medicus
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2. Full Text CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling
by Magalhaes, Ana C and Holmes, Kevin D and Dale, Lianne B and Comps-Agrar, Laetitia and Lee, Dennis and Yadav, Prem N and Drysdale, Linsay and Poulter, Michael O and Roth, Bryan L and Pin, Jean-Philippe and Anisman, Hymie and Ferguson, Stephen S.G
Nature neuroscience, ISSN 1097-6256, 05/2010, Volume 13, Issue 5, pp. 622 - 629
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Embryo, Mammalian | Amphetamines - pharmacology | Humans | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Anxiety - drug therapy | Receptors, Serotonin, 5-HT2 - metabolism | Serotonin - pharmacology | Dose-Response Relationship, Drug | Fluorobenzenes - pharmacology | Serotonin 5-HT2 Receptor Antagonists | Transfection | Piperidines - pharmacology | Reaction Time - drug effects | Behavior, Animal - drug effects | Inositol Phosphates - metabolism | Anxiety - metabolism | Cyclic AMP - metabolism | Ionophores - pharmacology | Disease Models, Animal | Hormones - pharmacology | Maze Learning - physiology | Neurons | Cells, Cultured | Anxiety - physiopathology | Monensin - pharmacology | Rats | Behavior, Animal - physiology | Maze Learning - drug effects | Mutation - genetics | Prefrontal Cortex - cytology | Corticotropin-Releasing Hormone - pharmacology | Receptors, Corticotropin-Releasing Hormone - physiology | Animals | Receptors, Serotonin, 5-HT2 - genetics | Serotonin Agents - pharmacology | Signal Transduction - drug effects | Signal Transduction - physiology | Biotinylation - methods | Mice | Serotonin 5-HT2 Receptor Agonists | Endocytosis | Physiological aspects | Cellular signal transduction | Anxiety | Genetic aspects | Research | Genetic regulation | Index Medicus
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3. Full Text 5-HT2 receptor regulation of mitochondrial genes: Unexpected pharmacological effects of agonists and antagonists
by Harmon, Jennifer L and Wills, Lauren P and McOmish, Caitlin E and Demireva, Elena Y and Gingrich, Jay A and Beeson, Craig C and Schnellmann, Rick G
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 04/2016, Volume 357, Issue 1, pp. 1 - 9
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Receptor, Serotonin, 5-HT2A - genetics | Male | Serotonin 5-HT2 Receptor Agonists - pharmacology | Gene Knockdown Techniques | Mitochondria - genetics | Electron Transport Complex I - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Female | Indoles - pharmacology | Receptor, Serotonin, 5-HT2A - drug effects | Kidney Tubules, Proximal - cytology | Rabbits | Receptor, Serotonin, 5-HT2C - drug effects | Oxidation-Reduction | Mice, Inbred C57BL | Oxygen Consumption | Mice, Transgenic | Transcription Factors - biosynthesis | Mitochondria - drug effects | Transcription Factors - genetics | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Piperazines - pharmacology | Gene Expression Regulation - drug effects | Animals | Aminopyridines - pharmacology | Electron Transport Complex I - biosynthesis | Kidney Tubules, Proximal - metabolism | Receptor, Serotonin, 5-HT2C - genetics | Pyrazines - pharmacology | Index Medicus | Drug Discovery and Translational Medicine
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4. Full Text Lorcaserin and pimavanserin: Emerging selectivity of serotonin receptor subtype-targeted drugs
by Meltzer, Herbert Y and Roth, Bryan L
The Journal of clinical investigation, ISSN 0021-9738, 12/2013, Volume 123, Issue 12, pp. 4986 - 4991
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Serotonin - physiology | Serotonin 5-HT2 Receptor Agonists - therapeutic use | Obesity - drug therapy | Benzazepines - adverse effects | Humans | Receptors, Serotonin - drug effects | Serotonin 5-HT2 Receptor Agonists - adverse effects | Serotonin 5-HT2 Receptor Agonists - pharmacology | Parkinson Disease - drug therapy | Piperidines - pharmacology | Urea - analogs & derivatives | Diabetes Mellitus, Type 2 - therapy | Heart Valve Diseases - chemically induced | Molecular Structure | Serotonin 5-HT2 Receptor Antagonists - adverse effects | Benzazepines - pharmacology | Parkinson Disease - psychology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Serotonin 5-HT2 Receptor Antagonists - therapeutic use | Urea - therapeutic use | Benzazepines - therapeutic use | Piperidines - therapeutic use | Piperidines - adverse effects | Urea - adverse effects | Schizophrenia - drug therapy | Diabetes Mellitus, Type 2 - drug therapy | Urea - pharmacology | Serotonin agonists | Obesity | Receptors | Parkinson's disease | Serotonin | Lorcaserin | Dosage and administration | Cellular signal transduction | Research | Properties | Drug therapy | Psychotropic drugs | Proteins | Heart | Lysergic acid diethylamide--LSD | Bias | Cloning | Technological change | Cardiovascular disease | Smooth muscle | Drug dosages | Index Medicus | Abridged Index Medicus | Review
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5. Full Text Kisspeptin1 modulates odorant‐evoked fear response via two serotonin receptor subtypes (5‐HT1A and 5‐HT2) in zebrafish
by Nathan, Fatima M and Ogawa, Satoshi and Parhar, Ishwar S
Journal of neurochemistry, ISSN 0022-3042, 06/2015, Volume 133, Issue 6, pp. 870 - 878
geriseum centrale | raphe | methysergide | olfactory | WAY 100635 | Olfactory | Geriseum centrale | Methysergide | Raphe | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Animals | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Zebrafish Proteins - metabolism | Behavior, Animal - drug effects | Behavior, Animal - physiology | Male | Zebrafish | Fear - physiology | Kisspeptins - metabolism | Receptors, Serotonin, 5-HT2 - metabolism | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Receptor, Serotonin, 5-HT1A - metabolism | Serotonin | Phenols | Neurochemistry | Index Medicus
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6. Full Text The neuropharmacology of sleep paralysis hallucinations: serotonin 2A activation and a novel therapeutic drug
by Jalal, Baland
Psychopharmacology, ISSN 0033-3158, 11/2018, Volume 235, Issue 11, pp. 3083 - 3091
Hypnopompic | Neurosciences | Hypnogogic | Hallucinogenic drugs | Biomedicine | Treatment | Sleep paralysis | Mystical experiences | Hallucinations | Serotonin 2A | Pharmacology/Toxicology | Psychiatry | Ketanserin | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Psilocybin - metabolism | Humans | Lysergic Acid Diethylamide - metabolism | Serotonin 5-HT2 Receptor Agonists - adverse effects | Serotonin 5-HT2 Receptor Agonists - pharmacology | Serotonin - pharmacology | Psilocybin - pharmacology | Piperidines - pharmacology | Urea - analogs & derivatives | Urea - metabolism | Sleep - physiology | Serotonin 5-HT2 Receptor Agonists - metabolism | Dopamine - metabolism | Sleep Paralysis - drug therapy | Hallucinations - drug therapy | Hallucinogens - pharmacology | Piperidines - metabolism | Dopamine - pharmacology | Hallucinations - chemically induced | Hallucinogens - metabolism | Hallucinations - metabolism | Neuropharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Sleep - drug effects | Sleep Paralysis - chemically induced | Serotonin 5-HT2 Receptor Antagonists - metabolism | Serotonin 5-HT2 Receptor Antagonists - therapeutic use | Sleep Paralysis - metabolism | Urea - therapeutic use | Animals | Lysergic Acid Diethylamide - pharmacology | Piperidines - therapeutic use | Serotonin - metabolism | Lysergic Acid Diethylamide - adverse effects | Receptor, Serotonin, 5-HT2A - metabolism | Urea - pharmacology | Receptors | Hallucinations and illusions | Sleep | Serotonin | Research | Drug therapy | Health aspects | Drugs | Visual cortex | Dopamine | Lysergic acid diethylamide--LSD | Lysergic acid diethylamide | Visual pathways | Positron emission | Activation | Lysergide | Serotonin S2 receptors | Fear | Chromosome 13 | Anxiety | Paralysis | Psilocybine | Positron emission tomography | Dopamine receptors | Index Medicus | Theoretical and Methodological
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7. Full Text 5-HT2 ligands in the treatment of anxiety and depression
by Quesseveur, Gaël and Nguyen, Hai T and Gardier, Alain M and Guiard, Bruno P
Expert opinion on investigational drugs, ISSN 1354-3784, 11/2012, Volume 21, Issue 11, pp. 1701 - 1725
anxiety | selective serotonin reuptake inhibitors | antidepressant | neurogenesis | depression | 5-HT2 receptors | atypical antipsychotics | monoamines | Antidepressant | Atypical antipsychotics | Depression | Selective serotonin reuptake inhibitors | Anxiety | Monoamines | Neurogenesis | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Serotonin 5-HT2 Receptor Agonists - therapeutic use | Brain - physiopathology | Humans | Anti-Anxiety Agents - pharmacology | Depressive Disorder - drug therapy | Serotonin 5-HT2 Receptor Agonists - pharmacology | Receptors, Serotonin, 5-HT2 - drug effects | Hippocampus - drug effects | Receptors, Serotonin, 5-HT2 - metabolism | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Antidepressive Agents - therapeutic use | Brain - drug effects | Hippocampus - metabolism | Serotonin 5-HT2 Receptor Antagonists - therapeutic use | Animals | Depressive Disorder - physiopathology | Adult | Antidepressive Agents - pharmacology | Neurogenesis - drug effects | Anti-Anxiety Agents - therapeutic use | Anxiety Disorders - drug therapy | Anxiety Disorders - physiopathology | Index Medicus
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